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The clinical briefing

Medical news

8,171 articles

Internal Medicine

Advancing Diagnosis in Metabolic Dysfunction-Associated Steatotic Liver Disease: Insights from the LITMUS Multicentre Study

The LITMUS study evaluates non-invasive biomarkers for diagnosing metabolic dysfunction-associated steatotic liver disease, highlighting proteomic panels’ promise in detecting at-risk steatohepatitis and fibrosis stages, potentially r

MedXY Editorial Team
Nov 6, 2026
Critical Care

Reducing Post-PICU Acute Care through Early Primary Care Follow-Up: Evidence from Pediatric Hospitalizations

Nov 6, 2026
Rheumatology

Targeting IL-4 Receptor-α in Localised Scleroderma: Promising Phase 2 Evidence for Fibrosis Modulation

Nov 6, 2026

Latest updates

OB/GYN & Women's Health

Optimizing Outcomes in Uterus Transplantation: Comprehensive Living Donor Evaluation from the Dallas Program

This article reviews the Dallas Uterus Transplant Program’s rigorous living donor evaluation process, highlighting its critical role in optimizing donor safety and recipient success in uterus transplantation.

Nov 6, 2026
Dermatology

Decoding Systemic Sclerosis: A New Vascular-Fibrotic Framework for Risk Stratification

This study introduces a novel classification framework for systemic sclerosis based on vascular and fibrotic complications, identifying a high-risk mixed endotype with distinct immunologic features and prognostic relevance, offering improve

Nov 6, 2026
Plastic Surgery

Enhancing Surgical Timing in Tissue Expansion with 3D Scanning-Based Predictive Modeling

A novel three-dimensional scanning workflow accurately predicts tissue expansion progress, optimizing surgical timing and improving reconstructive outcomes for congenital melanocytic nevus patients.

Nov 6, 2026
Psychiatry

Prefrontal Cortical Remodeling via Mindfulness-Oriented Recovery Enhancement in Opioid Use Disorder: Neurobiological and Clinical Insights from a Randomized Controlled Trial

Mindfulness-Oriented Recovery Enhancement (MORE) modulates prefrontal cortical activity, reduces craving, and prolongs abstinence in opioid use disorder by rebalancing neural responses to drug and natural rewards, substantiating its role as

Nov 6, 2026
Critical Care

Timely Antifungal Therapy Initiation Is Crucial in Improving Outcomes in Candida Septic Shock

Delayed appropriate antifungal therapy after the onset of persistent hypotension dramatically increases mortality in Candida septic shock; survival drastically improves with treatment within 2 hours.

Nov 6, 2026
Emergency Medicine

Ambient Artificial Intelligence Scribe Use and Objective Documentation Effort Among Emergency Physicians: A Multisite Evidence Synthesis

AI scribes reduce active documentation time among emergency physicians, delay note initiation without prolonging completion, and yield longer notes without increasing short-term readmissions, supporting efficient clinical documentation acro

Nov 6, 2026
Nursing & care

A Discrete Choice Experiment to Understand Hospital Discharge Preferences of Populations with Non-English Language Preference

This study quantifies hospital discharge communication preferences among patients with non-English language preferences, highlighting the importance of language-concordant instructions and family involvement to improve transitional care.

Nov 6, 2026
Hematology-Oncology

Human Milk Oligosaccharide 2′-Fucosyllactose (2′-FL) as a Modulator of Gut Microbiome and Immune Outcomes in Pediatric Allogeneic Hematopoietic Stem Cell Transplantation

2′-FL supplementation post-allo-HSCT preserves gut microbiome diversity, enriches beneficial taxa, reduces acute GI GVHD and viral reactivation, demonstrating safety and translational potential in pediatric transplant care.

Nov 6, 2026
Respiratory

Evaluating the Impact of a Self-Directed Weight Loss Intervention in Obstructive Sleep Apnea: Insights from the POWER Trial

The POWER trial assessed a self-directed lifestyle program for patients with OSA and obesity, finding modest improvements in sleep-related quality of life but limited clinically meaningful weight loss over 12 months.

Nov 6, 2026
Ophthalmology

Ophthalmic Encounters After Tamoxifen Initiation: Clinical Insights, Screening Practices, and Retinal Toxicity Risks

Tamoxifen-related retinal toxicity is known but ophthalmic evaluations after initiation are infrequent. Recent data reveal low screening rates, rare retinal-specific testing, and no greater ophthalmic use than aromatase inhibitors. Emerging

Nov 6, 2026
Otorhinolaryngology

Selective Auditory Temporal Processing Deficits in Vestibular Migraine: Insights and Implications

Vestibular migraine patients show impaired auditory temporal resolution despite normal hearing, highlighting central auditory processing involvement and suggesting potential for targeted auditory rehabilitation.

Nov 6, 2026
General Surgery

Unraveling Hospital-Level Differences in Medical Debt Post-Trauma: Insights from a Statewide Cohort Study

Significant variation exists in medical debt incurred by trauma patients depending on the hospital of treatment, highlighting modifiable factors in billing and financial practices that could mitigate financial hardship.

Nov 6, 2026
OB/GYN & Women's Health

Decoding Anti-Müllerian Hormone Trajectories During Menopause: Implications for Cardiovascular Health

Analysis of anti-müllerian hormone (AMH) trajectories reveals two distinct decline patterns across menopause, with slower AMH decline linked to higher postmenopausal cardiovascular risk, independent of premenopausal risk factors.

Nov 6, 2026
Gastroenterology

Targeting Myofibroblast-Derived Transglutaminase 2: A Novel Therapeutic Avenue for Intestinal Fibrosis in Stricturing Crohn’s Disease

This study reveals that elevated transglutaminase 2 activity from intestinal myofibroblasts drives fibrosis independent of inflammation in stricturing Crohn’s disease and that inhibiting TG2 can reduce fibrotic ECM accumulation, suggesting

Nov 6, 2026
Neurology

Noninvasive Exclusion of Arteriovenous Shunts in Intracerebral Hemorrhage Using MRI Arterial Spin Labeling: Insights from a Prospective Multicenter Study

Arterial spin labeling MRI enables reliable, noninvasive exclusion of arteriovenous shunts in intracerebral hemorrhage, potentially reducing reliance on invasive digital subtraction angiography.

Nov 6, 2026
Oncology

Evaluating Sunitinib for Advanced and Metastatic Pheochromocytomas and Paragangliomas: Efficacy, Safety, and Clinical Implications from Prospective Trials

This meta-analysis synthesizes prospective data on sunitinib treatment in metastatic pheochromocytomas and paragangliomas, revealing modest response rates and meaningful disease control with manageable safety profiles.

Nov 6, 2026
Cardiology

Integrated Resistance Training, Aerobic Exercise, and Sedentary Behavior Reduction Significantly Lower Cardiovascular Risk in U.S. Women

Consistent resistance training combined with recommended aerobic activity and low sedentary television viewing substantially reduces major cardiovascular events risk in women, particularly myocardial infarction.

Nov 6, 2026
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  4. 04Cardiology

    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

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    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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