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Dentistry

Innovations in Esthetic Zone Implantation: Digital Integration of the Socket-Shield Technique with Guided Immediate Implant Placement and One-Step Crown

This article reviews a novel digitally guided protocol combining the socket-shield technique and immediate implant placement in the esthetic zone, highlighting a 5-year successful clinical outcome and its implications for improving implant

MedXY Editorial Team
Oct 29, 2026

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Public Health

Wealth Redistribution Policies to Mitigate Health Impacts of Official Development Assistance Defunding: Evidence Synthesis and Future Projections to 2030

This review synthesizes evidence on the health impact of official development assistance defunding and evaluates wealth redistribution policies as mitigation strategies, forecasting millions of deaths averted by 2030 in low- and middle-inco

Oct 29, 2026
Pediatrics

Bidirectional Links Between Problematic Social Media Use and Adolescent Depression: A Longitudinal Perspective

This longitudinal cohort study reveals year-specific bidirectional associations between problematic social media use and depressive symptoms in adolescents, with stronger effects in females, while no prospective links were found for anxiety

Oct 29, 2026
Rheumatology

DNA Methylation Signatures Distinguish Gout from Asymptomatic Hyperuricaemia and Align with Genetic Risk at Immune-Metabolic Loci

This study identifies specific DNA methylation patterns in blood that differentiate gout patients from those with asymptomatic hyperuricaemia and normouricaemic controls, linking epigenetic changes to immune-metabolic genetic risk factors a

Oct 29, 2026
Nephrology

Raman Urine Fingerprinting: A Novel Predictive Tool for Delayed Graft Function and Renal Allograft Health Monitoring

Raman spectroscopy-based urine molecular fingerprinting offers a promising non-invasive biomarker to predict delayed graft function, assess baseline kidney allograft quality, and monitor transplant health postoperatively in patients receivi

Oct 29, 2026
Dermatology

Cobratide Injection versus Pregabalin for Acute Herpes Zoster Neuralgia: Insights from a Multicenter Exploratory Trial

This exploratory trial compares cobratide injection and pregabalin for moderate-to-severe acute herpes zoster neuralgia, showing similar pain relief with better tolerability for cobratide and a potential reduction in postherpetic neuralgia

Oct 29, 2026
Plastic Surgery

Rethinking Airway Management in Robin Sequence: Insights into Hyoid Morphology and Mandibular Distraction Osteogenesis

This article explores how mandibular distraction osteogenesis affects hyoid bone position and morphology in Robin Sequence, revealing new mechanisms by which airway patency improves beyond anterior hyoid movement.

Oct 29, 2026
Internal Medicine

Impact of the 2016 CDC Opioid Guideline on Analgesic Prescribing in Older Adults with Dementia: Trends and Clinical Implications

This study examines how the 2016 CDC opioid prescribing guideline influenced opioid and gabapentinoid use in older adults with dementia, revealing shifts in analgesic prescribing patterns but uncertain effects on symptom management.

Oct 29, 2026
Hematology-Oncology

Rapid Peak Cilta-Cel Expansion Predicts Delayed Neurotoxicity in Relapsed/Refractory Multiple Myeloma: Clinical and Translational Insights

Rapid and excessive expansion of ciltacabtagene autoleucel (cilta-cel) CAR T-cells associates with delayed neurotoxicity in relapsed/refractory multiple myeloma, with absolute lymphocyte count serving as a practical biomarker to guide early

Oct 29, 2026
Respiratory

Unveiling Respiratory Sensations in Adults with Congenital Central Hypoventilation Syndrome: Insights from Dyspnea Profiling During Rest and CO2 Rebreathing

This article explores the surprising presence of conscious respiratory unpleasantness and dyspnea in adults with congenital central hypoventilation syndrome (CCHS) despite severely impaired central CO2 chemosensitivity, revealing potential

Oct 28, 2026
Ophthalmology

Clinical Impact of Contact Lens Use in Fungal Keratitis: Insights from an 8-Year Retrospective Study

This study compares contact lens-associated and non-contact lens-associated fungal keratitis, highlighting earlier presentation and better medical therapy outcomes in contact lens users versus a more complicated course in non-users.

Oct 28, 2026
Pediatrics

Intubation Duration Trumps Tracheostomy in Predicting Neurodevelopmental Outcomes in Severe BPD

Prolonged intubation, rather than tracheostomy placement, is associated with poorer neurodevelopmental outcomes in infants with severe bronchopulmonary dysplasia, highlighting the need to reassess timing of airway interventions.

Oct 28, 2026
General Surgery

Temporary Portal Vein Bypass in Pancreatectomy: Enhancing Safety in Complex Pancreatic Cancer Surgery

Temporary mesoportal and mesocaval portal vein bypasses are effective surgical strategies in pancreatectomy with portal vein resection, offering comparable perioperative outcomes and facilitating safe resection of advanced pancreatic tumors

Oct 28, 2026
news

Optimizing Steroid Tapering Strategies for Immunotherapy Toxicities in Gynecologic Cancers

This study evaluates adherence to NCCN guidelines and taper durations of corticosteroids in managing severe immune-related adverse events (irAEs) among gynecologic cancer patients receiving immune checkpoint inhibitors, revealing that guide

Oct 28, 2026
Gastroenterology

Integrating Therapies for Alcohol Use Disorder in Alcohol-Associated Hepatitis Clinical Trials: Advancing Composite Endpoints for Improved Outcomes

Alcohol-associated hepatitis (AH) carries high morbidity and mortality, with no approved therapies addressing both liver injury and alcohol misuse. This article explores integrated trial designs using composite endpoints combining liver and

Oct 28, 2026
Clinical Updates

Differential Trajectories of Brain Atrophy in Multiple Sclerosis, MOGAD, and AQP4+ NMOSD: Unraveling the Impact of Disease Activity in MOGAD

This review synthesizes evidence comparing brain atrophy patterns in MS, MOGAD, and AQP4+ NMOSD, highlighting MOGAD’s atrophy association with inflammatory activity and lesion dynamics, emphasizing distinct pathogenic mechanisms and c

Oct 28, 2026
Clinical Updates

Low-Carbohydrate Diets, Nutritional Adequacy, Glycemia, and Perinatal Outcomes in Women With Gestational Diabetes Mellitus: Insights from the DiGest Trial and Contemporary Evidence

This review synthesizes current evidence on low-carbohydrate diets in gestational diabetes mellitus (GDM), highlighting effects on glycemia, nutrient adequacy, and perinatal outcomes from the DiGest trial and supporting literature.

Oct 28, 2026
Orthopedics

Enhanced Outcomes and Return-to-Sport Rates in Competitive Athletes Undergoing Contemporary Hip Arthroscopy for Femoroacetabular Impingement Syndrome

Contemporary hip arthroscopy techniques for femoroacetabular impingement syndrome (FAIS) in athletes yield superior patient-reported outcomes and higher return-to-sport rates compared to early methods, highlighting advances in surgical mana

Oct 28, 2026
Neurology

Companionship’s Crucial Role in Enhancing Psychosocial Health Among Individuals with Spinal Cord Injury

This study reveals companionship as a key mediator between marital status and mental health outcomes in individuals with spinal cord injury, highlighting the importance of relationship quality for psychosocial well-being.

Oct 28, 2026
Orthopedics

Enhancing Horizontal Ridge Augmentation: Efficacy of rhBMP-2 Loaded Volume-Stable Collagen Matrix Versus Guided Bone Regeneration

This preclinical canine study demonstrates that rhBMP-2 delivered via a volume-stable collagen matrix significantly improves horizontal ridge augmentation compared to conventional guided bone regeneration techniques, suggesting potential fo

Oct 28, 2026
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    Impact of Patient-Level Social Determinants on Colon Cancer Outcomes: A Novel Prognostic Measure Within an Integrated Health Network

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    Is Vaginal Laxity in Women Really Caused by Frequent Sex? Debunking a Common Myth

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