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Infectious Diseases

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Dermatology

When Secondary Syphilis is Reliably Recognizable: Clinical and Histopathologic Insights into Condyloma Lata

This review synthesizes evidence on the characteristic clinical and histopathologic features of condyloma lata in secondary syphilis, emphasizing its reliable recognition to prevent misdiagnosis, especially at extragenital sites.

MedXY Editorial Team
Nov 4, 2026Sign in to read

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Infectious Diseases

Immunogenicity and Safety of PHH-1V COVID-19 Vaccine as a Heterologous Booster in Adolescents

PHH-1V, a protein-based COVID-19 vaccine, is shown to be a safe and effective heterologous booster in adolescents, generating strong and lasting immune responses against multiple virus variants.

Oct 31, 2026
HIV/AIDS

Once-Weekly Oral Islatravir-Lenacapavir: A New Milestone in HIV-1 Treatment Simplification

A phase 3 trial demonstrates that once-weekly oral islatravir-lenacapavir is as effective and safe as daily bictegravir-emtricitabine-tenofovir alafenamide in maintaining HIV-1 viral suppression, offering a promising option to improve adher

Oct 29, 2026
Infectious Diseases

Evaluating Cytology and High-Risk HPV Testing in HPV-Vaccinated Young Women: Insights from a Scottish Prospective Study

This prospective Scottish study compares cytology and high-risk HPV testing performance in young HPV-vaccinated women, revealing high negative predictive value but lower positive predictive value of hrHPV testing, emphasizing the role of cy

Oct 27, 2026
Critical Care
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Shorter Is Often Better: Expert Consensus on Antibiotic Duration in Sepsis and Severe Infections in the ICU

A 2026 expert consensus recommends shorter, individualized antibiotic courses for most severe infections in critically ill patients, with clear exceptions and guidance on biomarkers, source control, and stewardship.

Oct 22, 2026
Infectious Diseases

Unprecedented Ebola Outbreak Originating in Congo Spreads Across Four Additional Nations

A fast-moving and geographically unprecedented Ebola outbreak that began in the Democratic Republic of the Congo has extended into four additional cou

Oct 21, 2026
Infectious Diseases

Medina County Identifies 18 Measles Cases Across Local Families Amid Persistent Ohio Outbreak

Public health officials in Medina County have detected an uptick in measles infections, confirming 18 total cases linked to a small cluster of familie

Oct 21, 2026
Infectious Diseases

Russia Investigates Suspected Mpox Outbreak Near Moscow as Five Are Hospitalized for Observation

Russian public health authorities have launched an extensive epidemiological investigation and rolled out containment protocols following a suspected

Oct 21, 2026
Infectious Diseases

Mpox Emerges in New Regions: High Impact on Children Sparks Concern as Experts Outline Containment and Prevention

A fresh outbreak of mpox has surfaced in Guinea-Bissau—the country's first recorded cases—bringing the viral infection back into the global spotlight.

Oct 21, 2026
Infectious Diseases

Unconfirmed Plague Suspicions Arise Following Lab Worker's Death in Siberia: What Experts Say

Health authorities worldwide are monitoring the death of a 28-year-old laboratory worker in Siberia, Russia, following reports of an undetermined case

Oct 21, 2026
Infectious Diseases

Exploring the Link Between Common Infections and Alzheimer’s Disease Neuropathology: Insights From a UK Prospective Cohort Study

A large-scale UK cohort study found no strong associations between antibodies against multiple common infections and key Alzheimer’s disease neuropathologies, though possible interactions with APOE ε4 genotype and education warrant further

Oct 21, 2026
Gastroenterology

Shortening Sofosbuvir-Velpatasvir Therapy for Non-Cirrhotic Chronic Hepatitis C: Evidence from the RESOLVE Trial in India

The RESOLVE trial demonstrates that 8 weeks of sofosbuvir-velpatasvir treatment is non-inferior to the standard 12-week regimen in treatment-naive, non-cirrhotic chronic hepatitis C patients, supporting shorter treatment duration without co

Oct 21, 2026
Gastroenterology

Reevaluating EASL 2025 Criteria: Benefits of Nucleos(t)ide Analogues in Chronic Hepatitis B Beyond Current Recommendations

This study demonstrates that nucleos(t)ide analogue therapy significantly reduces cirrhosis and hepatocellular carcinoma risk in specific HBeAg-positive chronic HBV infection phases beyond current EASL 2025 treatment indications.

Oct 20, 2026
Infectious Diseases

Dynamic Immune Modulation by Pegylated Interferon-Alpha Post-NUC Withdrawal in Chronic Hepatitis B

Pegylated interferon-alpha after nucleos(t)ide analog withdrawal induces coordinated expansion of regulatory B cells and contraction of HBV-specific T cells, impacting viral control and hepatic inflammation in HBeAg-negative chronic hepatit

Oct 19, 2026
HIV/AIDS

Long-Acting Injectable HIV Therapy: Improving Viral Suppression in African Adults with Adherence Challenges

A Phase 3b trial in eastern and southern Africa showed that long-acting injectable cabotegravir plus rilpivirine is noninferior to oral dolutegravir-based therapy for maintaining viral suppression in HIV patients facing adherence challenges

Oct 18, 2026
Clinical Updates

Long-Acting Injectable Cabotegravir-Rilpivirine Every 8 Weeks for Adolescents with HIV in Sub-Saharan Africa: Evidence from the LATA Trial and Contemporary Context

The LATA trial demonstrates that long-acting injectable cabotegravir-rilpivirine given every 8 weeks is superior to daily oral ART for maintaining virological suppression in adolescents with HIV in sub-Saharan Africa, with a favorable safet

Oct 17, 2026
Infectious Diseases

Amikacin Liposome Inhalation Suspension in Newly Diagnosed Mycobacterium avium Complex Lung Disease: Phase 3b ENCORE Trial

The ENCORE trial demonstrates that amikacin liposome inhalation suspension combined with multidrug therapy improves respiratory symptoms and culture conversion in newly diagnosed Mycobacterium avium complex lung disease patients.

Oct 17, 2026
Emergency Medicine

Evaluating Oral Cephalosporin Generations for Outpatient Pyelonephritis: Insights from the DOGMA-ED Study

A multicenter study shows similar 14-day treatment failure rates among first-, second-, and third-generation oral cephalosporins for outpatient pyelonephritis, supporting flexibility in antibiotic choice post-ED discharge.

Oct 13, 2026
Clinical Updates

Individualized Treatment Effects of Cefepime vs Piperacillin-Tazobactam in Adults Hospitalized with Acute Infection: A Review of Evidence and Clinical Implications

This review synthesizes evidence on how individual patient characteristics modify the comparative effects of cefepime versus piperacillin-tazobactam on acute kidney injury and neurologic outcomes in adults hospitalized with acute infection.

Oct 13, 2026
General Surgery

Reevaluating Postoperative Antibiotic Use After Appendectomy in Acute Appendicitis: Insights from a Large Retrospective Study

A large retrospective study shows no benefit of routine postoperative antibiotics after appendectomy for acute appendicitis, even with intra-abdominal fluid; highlights risk factors driving infections instead.

Oct 12, 2026