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This study examines differences in effect estimates between cluster-randomized and individually randomized clinical trials in prehospital, emergency, and critical care, revealing systematic bias in length-of-stay outcomes but not mortality.
US emergency departments increasingly discharge transient ischemic attack patients with extensive imaging, reflecting a shift from inpatient to expedited outpatient evaluation, raising questions about cost, feasibility, and rural healthcare
A randomized crossover study reveals that manual ventilation quality in pediatric respiratory arrest is suboptimal among EMS clinicians, but use of a ventilation feedback device significantly improves adherence to pediatric ventilation guid
The ICare-FASTER trial demonstrates that implementing point-of-care high-sensitivity cardiac troponin testing in emergency departments safely reduces patient length of stay by nearly 50 minutes without compromising 30-day cardiac safety out
This study develops and evaluates prognostic models combining clinical and toxicity information to predict complicated outcomes in ICU patients with acute intoxication, demonstrating the added value of laboratory data over toxicity scores a
This study assesses the safety, quality, and user acceptance of a conversational AI system aiding urgent primary care by engaging patients before appointments, demonstrating promising feasibility for clinical integration.
A large randomized trial finds no difference in 90-day days alive and out of hospital between early vasopressors with restricted fluids versus higher fluids with delayed vasopressors in septic shock, though pulmonary edema was less frequent
Acute Imbalance Syndrome represents over half of stroke-related vertigo cases, distinct from Acute Vestibular Syndrome by lesion location and clinical presentation, crucial for accurate stroke diagnosis in emergency care.
This review synthesizes evidence on the derivation and validation of a claims-based algorithm for identifying cardiogenic shock (CS), demonstrating its high diagnostic performance and enabling robust large-scale epidemiologic and long-term
Paramedic-suspected STEMI identified a heterogeneous, high-acuity population where 60% had confirmed STEMI; outcomes vary by final diagnosis, underscoring the need for rapid reperfusion with early diagnostic refinement.
This review synthesizes evidence on women Veterans’ emergency care utilization, comparing VA and Community ED use. It highlights demographic and clinical predictors influencing care settings and underscores the need for tailored coord
A multicenter study shows similar 14-day treatment failure rates among first-, second-, and third-generation oral cephalosporins for outpatient pyelonephritis, supporting flexibility in antibiotic choice post-ED discharge.
The PACER trial demonstrates that peer-supported internet-based CBT significantly reduces anxiety in ED patients with low-risk chest pain, with pronounced benefits in severe anxiety cases, supporting telehealth CBT as an effective anxiety t
The 2025 Italian consensus offers a reproducible, anatomy- and physiology-focused approach to appendiceal abscess management, clarifying imaging grading, escalation criteria, and when to operate, drain, or observe.
This review synthesizes evidence on racial disparities in prehospital trauma care, examining intervention rates, the influence of social determinants, and mortality outcomes with a focus on recent cohort data.
A clear, clinician-focused summary of the 2026 expert consensus on designing, conducting, and analyzing prehospital stroke trials in routine EMS systems—covering patient identification, consent, trial design, endpoints, and technology prior
This study identifies clinical and sociodemographic factors correlated with subsequent suicide attempts and mental health-related ED visits in youth screened positive for suicide risk in emergency departments, highlighting crucial targets f
This study explores how patient language preference affects the offer and acceptance of hepatitis C screening in emergency departments, highlighting disparities and suggesting targeted approaches to improve screening among non-English speak
The World Society of Emergency Surgery (2026) issues GRADE-based guidance favoring selective primary repair and physiology-guided reconstruction for most colon and rectal injuries, with CT-based diagnosis and limited routine diversion.
This randomized clinical trial demonstrates no clinically meaningful difference in pain relief between 20 mg intranasal and subcutaneous ketamine for acute musculoskeletal trauma in the emergency department, with minor adverse events being
