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This study demonstrates that arterial spin labeling spatial coefficient of variation (ASL-sCoV) correlates with cerebral small vessel disease burden and predicts cognitive decline over 11 years, outperforming traditional cerebral blood flow
Postacute discharge to inpatient rehabilitation facilities (IRF) after acute ischemic stroke (AIS) is associated with a reduced 1-year risk of major adverse cardiovascular events (MACE) compared to discharge to home or skilled nursing facil
This study analyzes national trends in emergent interfacility ischemic stroke transfers among Medicare beneficiaries, revealing shifts in transfer rates, patient characteristics, and hospital features associated with transferred versus nont
Kynurenic acid (KYNA) reduction in the gut correlates with worse poststroke outcomes. Supplementation activates a gut-brain neural circuit via GPR35 and the vagus nerve, promoting neuroprotection and functional recovery after ischemic strok
SGLT2 inhibitors administered after endovascular thrombectomy in diabetic stroke patients significantly improve 3-month functional outcomes, suggesting a promising adjunctive therapy for poststroke diabetes management.
This comparative analysis assesses ischemic stroke outcomes in patients with asymptomatic carotid stenosis undergoing transcarotid artery revascularization (TCAR) versus carotid artery stenting (CAS), highlighting no significant difference
This review synthesizes longitudinal evidence linking early adulthood vascular risks, particularly elevated systolic blood pressure and smoking, to midlife cognitive decline and brain structural alterations. It highlights critical intervent
The CREST-2 trial substantiates carotid artery stenting plus intensive medical management significantly reduces stroke risk in high-grade asymptomatic carotid stenosis compared to medical therapy alone, emphasizing patient selection and pro
A recent randomized trial shows that adding intravenous immunoglobulin (IVIG) to high-dose prednisone significantly improves muscle strength and disease activity in newly diagnosed idiopathic inflammatory myopathies with rapid and clinicall
In patients with distal and medium vessel occlusion strokes, tenecteplase achieves higher early recanalization rates and reduces early infarct growth compared to alteplase, supporting its preferential use in this clinical setting.
This study evaluates vessel wall MRI (VW-MRI) in pediatric arterial ischemic stroke, highlighting its diagnostic role in detecting inflammatory arteriopathies but limited prognostic value for long-term outcomes.
Analysis of two large cohorts reveals no significant association between levodopa use and freezing of gait in Parkinson’s disease after adjusting for disease severity and duration, emphasizing the primary role of disease progression in this
This study identifies glycine and specific lipid cholesterol proportions as metabolomic markers causally linked to lacunar stroke subtypes, enhancing understanding of cerebral small vessel disease pathogenesis and potential biomarkers.
A study using dual magnetic resonance spectroscopy reveals contrasting thalamic neuronal and bioenergetic profiles in painful versus painless diabetic peripheral neuropathy, highlighting potential biomarkers and mechanisms underlying neurop
A large retrospective study reveals anterior choroidal artery dilation as a key risk for rebleeding in hemorrhagic Moyamoya disease, with indirect revascularization (EDAS) significantly reducing rebleeding and improving outcomes.
This study delineates the clinical and radiographic profile of bibrachial amyotrophy (BBA) complicating spontaneous spinal cerebrospinal fluid (CSF) leaks and highlights the potential benefits of early surgical repair within 10 years of sym
A large European cohort study identifies six circulating metabolites significantly associated with future stroke risk, highlighting their potential in improving early stroke risk prediction beyond classic risk factors.
This study demonstrates that quantifying disconnected white matter fibers via high-resolution disconnectome analysis predicts 90-day outcomes and identifies thrombectomy responders better than conventional measures in acute basilar artery o
Older adults with severe nerve impairment in Bell’s palsy experience markedly poorer recovery, highlighting the critical role of early, aggressive intervention.
Electrodiagnostic tests, notably electroneuronography and electromyography, significantly improve prognosis prediction for Bell palsy recovery, including patients with moderate paralysis (H-B grade IV). These findings support broader use to
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