Section
MASLD has become a leading cause of liver transplantation in the US, with increasing transplant volumes and younger recipients. Despite relative stabilization in growth, survival post-transplant has improved, highlighting evolving epidemiol
This multicenter retrospective study shows that GLP-1 receptor agonists improve glycemic control and cardiometabolic parameters with good tolerance in heart transplant recipients with type 2 diabetes, supporting their therapeutic role in th
Combining serum leucine-rich alpha-2-glycoprotein 1 (LRG-1) with citrulline offers a sensitive, noninvasive biomarker strategy for early detection and monitoring of rejection in intestinal transplantation, potentially reducing reliance on i
Recent large-cohort analyses reveal that donor hospital distance from OPO headquarters does not increase deceased donor kidney nonuse, while policy changes like KAS250 temporarily raise nonuse rates but overall kidney utilization continues
This study explores myocardial external efficiency (MEE) and mitochondrial function in heart transplant recipients, revealing improved MEE at 6 months post-transplant associated with myocardial contractility and biomarkers, highlighting ene
An innovative, ultra-low-cost normothermic machine perfusion (NMP) system was developed and validated, enabling extended organ preservation and in vivo function in porcine and human tissues, offering affordable platforms for research and th
Raman spectroscopy-based urine molecular fingerprinting offers a promising non-invasive biomarker to predict delayed graft function, assess baseline kidney allograft quality, and monitor transplant health postoperatively in patients receivi
A new OPTN policy removing race from eGFR calculations shows promise in increasing kidney transplantation access for Black patients by adding waiting time credits, while not disadvantaging others on the waitlist.
Baseline lung allograft dysfunction (BLAD) affects over 60% of bilateral lung transplant recipients, associates with increased mortality, and influences long-term lung function trajectories. Risk factors include higher BMI, prolonged ICU st
Poor food access correlates with higher MASLD and frailty prevalence in liver transplant candidates, with geospatial clustering highlighting socioeconomic and environmental determinants impacting transplant candidacy and outcomes.
Complete pathologic response (cPR) after locoregional therapies notably improves survival in hepatocellular carcinoma (HCC) patients undergoing liver transplantation. Yttrium-90 radioembolization shows superior cPR rates, particularly when
This review synthesizes national data from Spain (2015-2024) revealing a decline in brain death donation (DBD) offset by growth in controlled donation after circulatory death (cDCD), alongside evolving neurocritical care practices influenci
This review presents a comprehensive ten-year update on global corneal transplantation and eye banking, highlighting persistent supply-demand gaps, income-based disparities, surgical trends, and emerging innovations to improve equitable acc
The Laennec technique offers a structured, anatomy-based robotic approach for right donor hepatectomies, demonstrating safety, feasibility, and zero biliary complications, potentially standardizing this complex procedure across centers.
This study evaluates nonvascularized rectus fascia allotransplantation (NVRF-alloTx) as an effective, versatile reconstructive option in both solid organ transplant and non-transplant patients, demonstrating promising integration and functi
Solid organ transplant recipients exhibit heightened risk for HPV-associated anal dysplasia and cancer due to unique immunosuppressive alterations. A transplant-tailored model of mucosal immune dysfunction elucidates mechanisms driving pers
Liver transplantation facilitates early neurocognitive recovery in end-stage liver disease patients by restoring cortical network activities, with S-methyl-5′-thioadenosine playing a pivotal neuroprotective role through modulating neu
Sequential use of normothermic regional perfusion and hypothermic machine perfusion in kidney transplants from DCD donors reduces delayed graft function, highlighting enhanced organ preservation strategies.
A multicenter study reveals that preserving donor hearts at 10°C results in better early graft function and one-year survival than traditional 4-8°C storage, suggesting a new standard for heart transplant preservation.
A machine-learning model using perioperative hemodynamic indices accurately predicted stage 2-3 acute kidney injury after orthotopic heart transplantation in 114 patients, with light gradient boosting machine achieving AUC 0.898.
