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The clinical briefing

Medical news

8,171 articles

Latest updates

Cardiology

Pregnancy Outcomes in Women with Preexisting Cardiomyopathy: Insights from a UK Prospective Cohort Study

This UK prospective study assesses pregnancy outcomes in women with preexisting cardiomyopathy, revealing generally favorable maternal and neonatal results with low cardiac complication rates and no maternal deaths.

Oct 24, 2026
Cardiology

Racial Disparities and Social Determinants in Cardiovascular Risk Among Women with Polyendocrine Metabolic Ovarian Syndrome

This study reveals significant racial differences in atherosclerotic cardiovascular disease risk among women with PMOS, highlighting that social determinants of health influence these disparities, particularly among Black women.

Oct 24, 2026
Cardiology

ICare-FASTER Trial: Revolutionizing Emergency Care with Point-of-Care High-Sensitivity Troponin Testing

The ICare-FASTER trial demonstrates that implementing point-of-care high-sensitivity cardiac troponin testing in emergency departments safely reduces patient length of stay by nearly 50 minutes without compromising 30-day cardiac safety out

Oct 24, 2026Sign in to read
news

Labral Tears and Cartilage Loss in Young High-Impact Athletes: Insights from the FORCe Longitudinal Study

This longitudinal study demonstrates a modest association between acetabular labral tears and cartilage loss in young high-impact athletes, highlighting the complexity of hip joint degeneration and the need for multifactorial prevention str

Oct 24, 2026
news

Evaluating Single Ultrasound-Guided Dextrose Prolotherapy Combined with Exercise in Subacromial-Subdeltoid Bursitis: Insights from a Pilot Double-Blind RCT

A pilot double-blind RCT suggests that adding a single ultrasound-guided dextrose prolotherapy injection to therapeutic exercise moderately improves shoulder pain and function in adults with subacromial-subdeltoid bursitis.

Oct 24, 2026
Dentistry

Microbial Network Insights Predict Peri-Implantitis Therapy Success: A One-Year Longitudinal Study

This study reveals that successful peri-implantitis surgical therapy is associated with distinct microbial network patterns, specifically increased connectivity and centrality of commensal bacteria, informing future microbiome-targeted appr

Oct 24, 2026
Diabetes & Endocrinology

Enhancing Glycemic Control in Non-Insulin-Treated Type 2 Diabetes with Continuous Glucose Monitoring: New Evidence from the CONNECT Trial

The CONNECT trial demonstrates that continuous glucose monitoring (CGM) significantly improves glycemic control in adults with non-insulin-treated type 2 diabetes managed in primary care, reducing HbA1c levels and hyperglycemia risk without

Oct 24, 2026
Clinical Updates

Lonvoguran Ziclumeran: A Breakthrough In Vivo CRISPR Gene-Editing Therapy for Hereditary Angioedema

Lonvoguran ziclumeran, an in vivo CRISPR-based single-dose gene-editing therapy, significantly reduces hereditary angioedema attacks and demonstrates a favorable safety profile, marking a transformative advance in treatment.

Oct 24, 2026
Hematology-Oncology

Prognostic Value of Early ST2 and REG3α Measurements in Haploidentical Stem Cell Transplantation with Post-Transplant Cyclophosphamide

Early increases in serum ST2 and REG3α within the first week after haploidentical stem cell transplantation with post-transplant cyclophosphamide predict transplant outcomes, highlighting their potential as prognostic biomarkers.

Oct 23, 2026
Rheumatology

Switching from Mepolizumab to Benralizumab in EGPA: A Promising Alternative for Persistent Respiratory Symptoms

In EGPA patients unresponsive to mepolizumab, switching to benralizumab improves lung function, reduces glucocorticoid use, and shows a favorable safety profile, suggesting its potential as an effective alternative treatment.

Oct 23, 2026
Ophthalmology

Impact of 24-Hour Blood Pressure Variability on Retinal Nerve Fiber Layer Progression in Primary Open-Angle Glaucoma

Lower systemic blood pressure, especially minimum values measured over 24 hours, is associated with accelerated retinal nerve fiber layer loss in primary open-angle glaucoma, highlighting the prognostic value of ambulatory BP monitoring.

Oct 23, 2026
Otorhinolaryngology

Advancing Ear Disease Diagnosis: Optical Coherence Tomography Enables Quantitative, Point-of-Care Tympanic Membrane Imaging

Optical coherence tomography (OCT) otoscopy delivers rapid, quantitative imaging of the tympanic membrane, distinguishing normal and diseased ears, improving diagnostic accuracy, and allowing longitudinal monitoring of middle ear pathologie

Oct 23, 2026
General Surgery

Impact of Cholecystitis Treatment on Continuation of Cancer Therapy: Insights from a Decade-long Institutional Study

This study evaluates how treatment for cholecystitis affects the timely resumption of cancer therapy, highlighting that half of cancer patients return to therapy within six weeks, with hematologic malignancies and drainage procedures linked

Oct 23, 2026
Neurology

Expert Consensus on Managing Spontaneous Intracranial Hypotension with Spinal Longitudinal Epidural CSF Collections: Key Recommendations from a 2026 Delphi Study

An international Delphi panel offers practical, evidence-informed recommendations for managing spontaneous intracranial hypotension with spinal longitudinal epidural CSF collections, clarifying peri-epidural blood patch practice, imaging ch

Oct 23, 2026
Diabetes & Endocrinology

Hippocampal Structural Alterations and White Matter Changes in Congenital Adrenal Hyperplasia: Insights into Sex-Specific Brain Vulnerabilities

This study reveals significant hippocampal subfield volume reductions and white matter impairments in patients with congenital adrenal hyperplasia, highlighting sex-specific differences that could influence cognitive outcomes and treatment

Oct 23, 2026
Cardiology

Aldosterone Levels and Mineralocorticoid Receptor Antagonists in Heart Failure: Implications for Personalized Therapy

This article explores how baseline aldosterone concentrations influence the efficacy and outcomes of mineralocorticoid receptor antagonists (MRAs) in heart failure patients, highlighting the need for tailored therapeutic approaches.

Oct 23, 2026
Rehabilitation Medicine

Exploring Reticulospinal Tract Plasticity: Effects of Short-Term Isometric Resistance Training on Neural Adaptations

This study evaluated whether 4 weeks of unilateral isometric elbow flexion resistance training induce adaptations in human reticulospinal tract function, finding no significant changes despite strength gains, thus informing neurorehabilitat

Oct 23, 2026
Rehabilitation Medicine

Bridging the Gap: Physiotherapists’ Views on Direct Access in Austria’s Referral-Based Care System

This qualitative study explores Austrian physiotherapists’ perspectives on direct access, revealing existing informal practice, confidence levels, organizational barriers, and training needs critical for policy reforms.

Oct 23, 2026
Dentistry

Optimizing Management of Medication-Related Osteonecrosis of the Jaw: Insights from a Single-Center Retrospective Cohort

This study evaluates outcomes of medication-related osteonecrosis of the jaw (MRONJ) treatments in 222 patients, highlighting the superiority of surgical interventions over conservative therapy, especially in osteoporosis-associated cases.

Oct 23, 2026
Critical Care

Intraoperative Dobutamine Plus Norepinephrine Significantly Reduces Postoperative Acute Kidney Injury in Septic Shock: Insights from a Multicenter Randomized Trial

A randomized clinical trial demonstrates that adding intraoperative dobutamine to norepinephrine during surgical source control for septic shock significantly decreases postoperative acute kidney injury incidence and severity.

Oct 23, 2026
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  4. 04Cardiology

    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

  5. 05General Surgery

    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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