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The clinical briefing

Medical news

8,171 articles

Latest updates

Pediatrics

Neonatal Medical Male Circumcision and Autism Spectrum Disorder: Evaluating the Evidence from a Prospective Cohort Study

A large prospective cohort study found no evidence linking neonatal medical male circumcision with increased risk of autism spectrum disorder or autism-related traits in children, providing reassurance for families and clinicians.

Oct 23, 2026
Internal Medicine

Ultrasound-Derived Renal Parenchymal Volume Indexed to BMI: A Novel Predictor of One-Year Kidney Graft Function

Indexing donor kidney parenchymal volume by recipient BMI via routine ultrasound strongly predicts one-year kidney graft function, offering a practical surrogate for graft-recipient size matching.

Oct 23, 2026
Dermatology

Telehealth Behavioral Intervention for Melanoma Prevention in Children of Survivors: Insights from a Randomized Clinical Trial

A telehealth intervention improved sun-protective behaviors among children of melanoma survivors but did not sustain reductions in sunburn rates compared to education alone, highlighting the challenge of long-term melanoma prevention in hig

Oct 23, 2026
Superintelligence

Navigating the Future: Medical and Legal Implications of Artificial Intelligence in Plastic Surgery

This article explores the expanding role of artificial intelligence in plastic surgery, detailing medical benefits, legal risks, and strategies for risk mitigation to protect patients and practitioners.

Oct 23, 2026
Critical Care

Predicting Outcomes in Acutely Intoxicated ICU Patients: Integrating Toxicity Scores and Laboratory Data

This study develops and evaluates prognostic models combining clinical and toxicity information to predict complicated outcomes in ICU patients with acute intoxication, demonstrating the added value of laboratory data over toxicity scores a

Oct 23, 2026
Internal Medicine

Integrating Pharmacists into Opioid Use Disorder Care: Feasibility and Acceptability in Primary Care Settings

A nonrandomized clinical trial demonstrates that incorporating pharmacists into primary care teams to manage opioid use disorder enhances feasibility, reduces care barriers, and maintains high acceptability among providers and patients.

Oct 23, 2026
Hematology-Oncology

Predicting Outcomes in Advanced Systemic Mastocytosis with KIT Inhibitors: Insights from Genetic and Laboratory Monitoring

This article reviews how genetic profiling and dynamic laboratory markers predict clinical outcomes in advanced systemic mastocytosis treated with KIT inhibitors avapritinib and midostaurin, facilitating optimized treatment strategies.

Oct 23, 2026
Critical Care

Continuous Automatic Endotracheal Cuff Pressure Monitoring Reduces Ventilator-Associated Pneumonia in Pediatric ICU: New Evidence from a Robust RCT

Continuous automatic cuff pressure monitoring significantly lowers ventilator-associated pneumonia incidence in critically ill children by ensuring better pressure control, offering an effective preventive strategy in pediatric intensive ca

Oct 23, 2026
Diabetes & Endocrinology

Evaluating Anti-VEGF Retreatment Outcomes in Diabetic Macular Edema Patients Returning After Lost to Follow-Up with Stabilized Vision

This nationwide study examines visual and anatomical responses to anti-VEGF retreatment in diabetic macular edema patients who returned with stabilized vision after being lost to follow-up, highlighting suboptimal gains and implications for

Oct 23, 2026
Clinical Updates

Integrating Body Composition Metrics for Prognostication in Head and Neck Cancer Radiotherapy: Advances and Clinical Implications

Recent evidence highlights the prognostic significance of body composition metrics, including BMI, skeletal muscle mass, and adiposity distribution, in head and neck cancer radiotherapy outcomes. Automated 3D CT phenotyping refines risk str

Oct 22, 2026
Gastroenterology

Optimizing Treatment Strategies for Gastric Cancer with Positive Peritoneal Cytology or Localized Peritoneal Metastasis

This article reviews a multicenter study comparing outcomes of different treatment approaches for gastric cancer patients with positive peritoneal cytology (CY1) and/or localized peritoneal metastasis (P1a), highlighting the superior surviv

Oct 22, 2026
Cardiology

Predicting 10-Year Risk of Hypertension in Women Post-Pregnancy: Insights from a Population-Based Cohort Study

Incorporating pregnancy-related factors, especially hypertensive disorders of pregnancy, significantly improves the prediction of 10-year incident hypertension risk in women after their first childbirth, potentially guiding targeted cardiov

Oct 22, 2026
Critical Care

Adjuvant Systemic Hypothermia During Mechanical Thrombectomy: Feasibility and Clinical Insights from the ReCCLAIM II Trial

The ReCCLAIM II trial demonstrates that rapid systemic hypothermia during mechanical thrombectomy for large-vessel occlusion stroke is feasible without delaying reperfusion, showing trends toward reduced infarct volume but raising safety co

Oct 22, 2026
Diabetes & Endocrinology

Long-Term Outcomes and Calcification Dynamics After Radiofrequency Ablation of Calcified Papillary Thyroid Microcarcinomas

This retrospective study demonstrates that radiofrequency ablation (RFA) effectively treats low-risk papillary thyroid microcarcinomas (PTMC), including those with intratumoral calcifications, with excellent technical success, significant t

Oct 22, 2026
Cardiology

Genotype and Arrhythmic Risk in Dilated Cardiomyopathy: An Integrative Review of Genetic Stratification and Clinical Implications

Genetic variants in dilated cardiomyopathy confer differential arrhythmic risks, independent of traditional clinical parameters. Integrating recent registry data and molecular studies enhances risk stratification and informs tailored manage

Oct 22, 2026
news

Safety and Gait Outcomes of Adding Lateral Extra-articular Tenodesis in Pediatric ACL Reconstruction: Motion Analysis Insights

In pediatric ACL reconstruction, adding lateral extra-articular tenodesis (LET) does not alter early gait biomechanics, supporting its safety for improving knee stability without adverse gait effects.

Oct 22, 2026
Neurology

Influence of Age, Resilience, Social Support, and Health Literacy on Functional Recovery Following Traumatic Spinal Cord Injury: Insights from a 6-Month Follow-up Study

A 6-month longitudinal study identifies younger age, higher resilience, and better health literacy as key predictors of functional ability improvement in traumatic spinal cord injury patients, highlighting targets for tailored rehabilitatio

Oct 22, 2026
Dentistry

Three-Year Clinical Evaluation of Universal Adhesive Performance Using Optical Coherence Tomography

A 36-month clinical trial using optical coherence tomography (OCT) reveals superior performance of Scotchbond™ Universal Adhesive in selective enamel-etch mode for restoring cervical lesions, with lower bond failure and adhesive defects com

Oct 22, 2026
Clinical Updates

Cardiovascular Safety and Therapeutic Potential of Orforglipron Versus Insulin Glargine in Type 2 Diabetes with Elevated Cardiovascular Risk: Insights from the ACHIEVE-4 Phase 3 Trial

A comprehensive review of the ACHIEVE-4 trial confirms orforglipron’s cardiovascular safety non-inferior to insulin glargine in type 2 diabetes patients at elevated cardiovascular risk, highlighting its oral administration and safety

Oct 22, 2026
Dermatology

Efficacy and Tolerability of Long-Term Low-Dose Capecitabine for Refractory Cutaneous Field Cancerization: Insights from a Retrospective Cohort Study

This study demonstrates that long-term, low-dose capecitabine significantly reduces keratinocyte carcinoma surgeries in patients with refractory cutaneous field cancerization and is generally well tolerated, offering a promising therapeutic

Oct 22, 2026
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  4. 04Cardiology

    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

  5. 05General Surgery

    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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