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Medical news

8,171 articles

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Transplantation

Serum LRG-1 and Citrulline Ratio: A Breakthrough Biomarker Duo for Intestinal Transplant Rejection Monitoring

Combining serum leucine-rich alpha-2-glycoprotein 1 (LRG-1) with citrulline offers a sensitive, noninvasive biomarker strategy for early detection and monitoring of rejection in intestinal transplantation, potentially reducing reliance on i

Nov 3, 2026
Dermatology

Risk Factors and Clinical Profile of Infantile Hemangioma Ulceration Post Oral Propranolol Treatment: Insights from a Large Retrospective Study

This retrospective study evaluates the incidence and risk factors for infantile hemangioma ulceration following oral propranolol therapy, highlighting subtype-related risks and anatomical protective factors to guide clinical management.

Nov 3, 2026
Plastic Surgery

Advancing Hair Loss Therapy: Sodium Citrate Enhances Comfort and Efficacy of Concentrated Growth Factor Treatment in Androgenetic Alopecia

In a randomized trial, sodium citrate as an anticoagulant in concentrated growth factor therapy for androgenetic alopecia reduced injection pain, improved hair density, and increased patient satisfaction compared with heparin sodium or no a

Nov 3, 2026
Critical Care

Mitochondrial Dysfunction and Platelet Hyperactivation: A Novel Therapeutic Target in Sepsis

Sepsis triggers mitochondrial impairment in platelets, promoting hyperactivation via ROS production. The mitochondria-specific antioxidant MitoTEMPO reverses these changes in vitro, suggesting therapeutic potential to prevent sepsis-related

Nov 3, 2026
Cardiology

Assessing Cardiovascular Risk Prediction Models in Postmenopausal Women With Chronic Kidney Disease: Insights from the Women’s Health Initiative

Cardiovascular risk prediction models show limited accuracy in postmenopausal women with chronic kidney disease, often underestimating risk, highlighting the need for improved tools in this high-risk population.

Nov 3, 2026
Hematology-Oncology

Unraveling Donor Cell-Derived Hematologic Neoplasms: Insights from Spanish Transplant Centers

This nationwide study reveals that donor cell-derived hematologic neoplasms (DDHN) after allogeneic stem cell transplantation are rare but linked mainly to inherited germline mutations in related donors, underscoring the need for comprehens

Nov 3, 2026
Cardiology

Targeting the Macrophage YTHDC1/TIGAR/NF-κB Axis: A Novel Therapeutic Strategy for Pulmonary Hypertension

This article explores the role of the macrophage YTHDC1/TIGAR/NF-κB axis in pulmonary hypertension and highlights its potential as a therapeutic target to mitigate inflammation-driven vascular remodeling.

Nov 3, 2026
Ophthalmology

Clinical Validation of the UCI Corneal Cystine Crystal Score: Linking Objective Imaging and Symptom Burden in Cystinosis

The University of California, Irvine Corneal Cystine Crystal Score (UCI CCCS) is validated as a reliable slit-lamp grading tool correlating with corneal densitometry and symptoms in cystinosis, though not visual acuity, highlighting its val

Nov 3, 2026
Otorhinolaryngology

Exploring the Impact of Psychosocial Stress on Vocal Fold Epithelium: Insights from Germ-Free and Conventionally-Raised Mice

This study reveals that psychosocial stress induces vocal fold epithelial barrier dysfunction irrespective of microbiota presence, while microbiota presence uniquely promotes stress-induced epithelial proliferation in vocal folds, suggestin

Nov 3, 2026
Gastroenterology

Comparative Efficacy of Subtotal Versus Total Colectomy for Slow-Transit Constipation: Insights from the STOPS Randomized Clinical Trial

The STOPS trial demonstrates noninferiority of subtotal colectomy with cecorectal anastomosis compared to total colectomy with ileorectal anastomosis for refractory slow-transit constipation at 1 year, balancing symptom relief with postoper

Nov 3, 2026
OB/GYN & Women's Health

Intraoperative Iodine Staining During LEEP: A Randomized Trial Challenging Its Routine Use

A randomized trial shows that intraoperative Lugol’s iodine staining during LEEP increases positive resection margins and should not be routinely applied, despite reducing postoperative bleeding duration.

Nov 3, 2026
Gastroenterology

Dietary Intervention Lowers Intestinal Inflammation in High-Risk Relatives of Crohn’s Disease Patients: Insights from the PIONIR Trial

The PIONIR randomized crossover trial demonstrates that a specific Tasty&Healthy diet significantly reduces fecal calprotectin levels, a marker of gut inflammation, in first-degree relatives at high risk for Crohn’s disease, sugge

Nov 3, 2026
Neurology

Self-Guided Internet-Based Therapy Significantly Reduces Functional Seizures: Insights from a Randomized Clinical Trial

A randomized clinical trial demonstrates that a self-guided internet intervention significantly reduces seizure frequency and improves anxiety in adults with functional seizures, offering a scalable treatment alternative to standard care.

Nov 3, 2026
Diabetes & Endocrinology

Comparative Effectiveness of Semaglutide versus Dulaglutide or Liraglutide in Hemodialysis Patients with Diabetes

This study evaluates semaglutide’s benefits over dulaglutide or liraglutide among diabetic hemodialysis patients, highlighting improved survival, reduced hospitalizations, and greater weight loss with semaglutide.

Nov 3, 2026
Cardiology

Modulating Coronary Artery Calcification Progression: Insights from the DANCODE Trial on Vitamin K2 and D3 Supplementation

The DANCODE trial demonstrates that combined vitamin K2 and D3 supplementation reduces the progression of severe coronary artery calcification over 24 months without increasing noncalcified plaque burden, offering a promising adjunctive str

Nov 3, 2026
Orthopedics

Evaluating the Global Track Concept in Anterior Shoulder Instability with Glenohumeral Bone Loss: Implications for Clinical Decision-Making

This study assesses the global track measurement against traditional imaging metrics to better predict engagement risk in anterior shoulder instability due to bipolar bone loss, highlighting its potential and need for further validation.

Nov 3, 2026
Nursing & care

Evaluating Rehabilitation Outcomes: Inpatient Rehabilitation Facilities Versus Skilled Nursing Facilities Post-Acute Stroke

This study compares the effectiveness of inpatient rehabilitation facilities and skilled nursing facilities on functional recovery after acute stroke, showing inpatient care offers greater long-term home time.

Nov 3, 2026
Oncology

Oral Irrigation Enhances Microbiome Stability and Recovery After Oral Cancer Reconstruction

Surgical trauma from oral cancer reconstruction disrupts oral microbiota; staged oral irrigation, especially using bipolar water, supports microbial stabilization, lowers fungal presence, and improves patient comfort, aiding postoperative r

Nov 3, 2026
Oncology

Divarasib Compared with Sotorasib and Adagrasib in KRAS G12C-Mutated NSCLC: A Comprehensive Clinical and Translational Review

This review synthesizes phase 3 clinical evidence comparing divarasib, sotorasib, and adagrasib for KRAS G12C-mutated NSCLC, highlighting divarasib’s superior efficacy and safety, dose optimization insights, real-world data, and trans

Nov 3, 2026
Respiratory

eHealth-Guided Exercise Enhances Peak Oxygen Uptake and Quality of Life Post-COVID-19: A Randomized Controlled Trial

This trial shows that a six-month eHealth-guided exercise program significantly improves peak oxygen uptake and mental health quality of life in adults recovering from COVID-19, outperforming standard physical activity advice.

Nov 2, 2026
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    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

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    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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