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Social Inequalities in Gestational Diabetes: Insights from a Nationwide Swedish Cohort Study
Diabetes & Endocrinologyhealth disparitiespregnancy complications

Social Inequalities in Gestational Diabetes: Insights from a Nationwide Swedish Cohort Study

By MedXY|Sep 17, 2026

This Swedish cohort study reveals growing gestational diabetes prevalence with marked disparities by social determinants such as education, income, and nativity, underscoring the need for targeted prevention and equitable care.

Oxytocin’s Role in Modulating Thyroid Function and Mental Health in Obesity: Insights from an 8-Week Clinical Trial
Diabetes & Endocrinologyobesitythyroid function

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news6629 articlesCardiology1375 articlesClinical Updates1288 articlesOncology1139 articlesDiabetes & Endocrinology842 articlesNeurology820 articlesPublic Health595 articlesGastroenterology572 articles

Oxytocin’s Role in Modulating Thyroid Function and Mental Health in Obesity: Insights from an 8-Week Clinical Trial

By MedXY|Sep 17, 2026

An 8-week trial reveals that intranasal oxytocin increases the free T3/free T4 ratio and correlates with improved mental health-related quality of life in adults with obesity, suggesting thyroid axis modulation as a potential mechanism for

Impact of an AI-Powered Gamified Mobile Health Application on Blood Pressure Control in a Matched Patient Cohort
AIdigital healthHypertension

Impact of an AI-Powered Gamified Mobile Health Application on Blood Pressure Control in a Matched Patient Cohort

By MedXY|Sep 17, 2026

Study found that use of an AI-driven gamified mobile app integrating home blood pressure monitoring significantly improved blood pressure control compared to usual care in hypertensive patients.

Enabling Technologies in Community Health Centers: Overcoming Barriers to Address Social Determinants of Health in Care-Managed Patients
news健康の社会的決定要因care management

Enabling Technologies in Community Health Centers: Overcoming Barriers to Address Social Determinants of Health in Care-Managed Patients

By MedXY|Sep 17, 2026

This article examines how community health centers use electronic health record tools to address patients’ social needs through care management programs, identifying barriers and proposing targeted implementation strategies to enhance

Timing of Initiation of Methadone Take-Home Dosing: Evidence Synthesis and Clinical Implications for Opioid Use Disorder Management
Anesthesiologyopioid use disordertreatment retention

Timing of Initiation of Methadone Take-Home Dosing: Evidence Synthesis and Clinical Implications for Opioid Use Disorder Management

By MedXY|Sep 17, 2026

Early initiation of methadone take-home dosing (5-24 weeks post-induction) reduces mortality and treatment discontinuation, surpassing benefits seen with no take-home dosing. Flexible dosing policies improve retention without increasing ove

Mindfulness Group Visits: A New Approach to Chronic Low Back Pain Relief
Internal Medicinetelehealthmindfulness

Mindfulness Group Visits: A New Approach to Chronic Low Back Pain Relief

By MedXY|Sep 17, 2026

A randomized trial found telehealth mindfulness group visits improve chronic low back pain more than usual care, highlighting a scalable, non-drug treatment option.

Impact of Digitalis Glycosides on Cardiovascular Outcomes in HFmrEF and HFrEF: A Comprehensive Evidence Synthesis
Cardiologydigitalis glycosidesheart failure with mid-range ejection fraction

Impact of Digitalis Glycosides on Cardiovascular Outcomes in HFmrEF and HFrEF: A Comprehensive Evidence Synthesis

By MedXY|Sep 17, 2026

Digitalis glycosides reduce cardiovascular death or worsening heart failure events in HFmrEF and HFrEF patients over a median of 36–37 months, supported by randomized trials and meta-analyses highlighting their role in select heart failure

ATG versus Alemtuzumab for GvHD Prophylaxis in AML Allo-HCT: Insights from the EBMT Registry
Hematology-OncologyAllogeneic Hematopoietic Cell TransplantationBệnh Graft-versus-Host

ATG versus Alemtuzumab for GvHD Prophylaxis in AML Allo-HCT: Insights from the EBMT Registry

By MedXY|Sep 17, 2026

In AML patients undergoing unrelated donor allo-HCT with intermediate-intensity conditioning, ATG-based GvHD prophylaxis demonstrated better overall and leukemia-free survival and reduced relapse compared to alemtuzumab, despite higher acut

Optimizing GVHD Prophylaxis after Reduced-Intensity Matched Donor Transplantation in AML and MDS: Insights from PTCy and ATG Strategies
Hematology-OncologyGVHD prophylaxisMDS

Optimizing GVHD Prophylaxis after Reduced-Intensity Matched Donor Transplantation in AML and MDS: Insights from PTCy and ATG Strategies

By MedXY|Sep 17, 2026

A large registry analysis supports post-transplant cyclophosphamide (PTCy) as an effective alternative to anti-thymocyte globulin (ATG) for preventing graft-versus-host disease (GVHD) in reduced-intensity conditioning matched donor peripher

Germline Lymphoma-Predisposing Variants: Influence on Age at Diagnosis and Survival Outcomes in Pediatric Patients
Clinical Updatessurvival outcomescancer genetics

Germline Lymphoma-Predisposing Variants: Influence on Age at Diagnosis and Survival Outcomes in Pediatric Patients

By MedXY|Sep 17, 2026

This review synthesizes current evidence on germline lymphoma-predisposing variants, highlighting their impact on earlier cancer onset and variable survival rates in pediatric lymphoma patients, underscoring implications for genetic screeni

Comparing CHOP and CHOEP/EPOCH Regimens in Aggressive Adult T-Cell Leukemia/Lymphoma: Insights from an International Cohort Study
Hematology-Oncologychemotherapysurvival outcomes

Comparing CHOP and CHOEP/EPOCH Regimens in Aggressive Adult T-Cell Leukemia/Lymphoma: Insights from an International Cohort Study

By MedXY|Sep 17, 2026

This international cohort study evaluates the effectiveness of CHOEP/EPOCH versus CHOP chemotherapy in aggressive adult T-cell leukemia/lymphoma, revealing subtype-specific survival benefits in lymphomatous ATL but inconclusive results in a

Unraveling the Role of Cohesin Mutations in HLA-Class II Downregulation and Leukemia Progression in Down Syndrome
Hematology-OncologyBệnh bạch cầu dòng tủyCohesin mutations

Unraveling the Role of Cohesin Mutations in HLA-Class II Downregulation and Leukemia Progression in Down Syndrome

By MedXY|Sep 17, 2026

This article explores how cohesin mutations impair HLA-class II gene expression, contributing to leukemic progression from transient abnormal myelopoiesis to myeloid leukemia in children with Down syndrome.

Tisagenlecleucel for Post-Transplant Relapse in Young Acute Lymphoblastic Leukemia Patients: European Real-World Determinants of Outcome
Hematology-Oncologyhematopoietic stem cell transplantCAR-T Therapy

Tisagenlecleucel for Post-Transplant Relapse in Young Acute Lymphoblastic Leukemia Patients: European Real-World Determinants of Outcome

By MedXY|Sep 17, 2026

This study evaluates the outcomes and critical factors influencing the success of tisagenlecleucel therapy for children and young adults with B-cell acute lymphoblastic leukemia relapsing after hematopoietic stem cell transplant across Euro

FAP-1 Deficiency: A Novel Mechanistic Link to Impaired Megakaryocyte Maturation, Platelet Dysfunction, and Myelofibrosis-like Disease
Hematology-OncologyFAP-1Src kinase

FAP-1 Deficiency: A Novel Mechanistic Link to Impaired Megakaryocyte Maturation, Platelet Dysfunction, and Myelofibrosis-like Disease

By MedXY|Sep 17, 2026

Loss of FAP-1 disrupts megakaryocyte membrane development and platelet function through aberrant Src activation, leading to myelofibrosis-like pathology with potential therapeutic targeting by Src inhibition.

Targeting ACKR3/CXCR7 Enhances Platelet Anticoagulant Lipids and Modulates Procoagulant Function: Implications for Thrombosis Management
CardiologyACKR3acylcarnitines

Targeting ACKR3/CXCR7 Enhances Platelet Anticoagulant Lipids and Modulates Procoagulant Function: Implications for Thrombosis Management

By MedXY|Sep 17, 2026

Pharmacological activation of CXCR7 regulates platelet lipid metabolism, preserves mitochondrial function, and reduces procoagulant activity, offering a novel therapeutic strategy to mitigate thrombotic risk in cardiovascular diseases.

Early Biologic Initiation in Severe Asthma: Enhancing Remission and Clinical Outcomes from Global Real-World Cohorts
Clinical Updatesearly interventionClinical Remission

Early Biologic Initiation in Severe Asthma: Enhancing Remission and Clinical Outcomes from Global Real-World Cohorts

By MedXY|Sep 17, 2026

Earlier initiation of biologic therapies in severe asthma improves clinical remission rates, reduces exacerbations, preserves lung function, and decreases corticosteroid dependence, supporting a shift from reserving to preserving treatment

Enhancing Palliative Care in the ICU: Insights From Specialist Clinicians on Integration and Impact
Critical Carepalliative careSpecialty Consultation

Enhancing Palliative Care in the ICU: Insights From Specialist Clinicians on Integration and Impact

By MedXY|Sep 17, 2026

This multi-institutional qualitative study explores specialty palliative care clinicians’ perspectives on optimizing their role in the ICU, highlighting strategic consultation timing, shared understanding with intensivists, and embedd

Extracorporeal Membrane Oxygenation without Mechanical Ventilation in ARDS: Insights from an International Cohort Study
Critical CareExtubationARDS

Extracorporeal Membrane Oxygenation without Mechanical Ventilation in ARDS: Insights from an International Cohort Study

By MedXY|Sep 17, 2026

This study evaluates ECMO as a standalone respiratory support in ARDS patients avoiding invasive mechanical ventilation, highlighting outcomes, strategy failures, and mortality implications.

From Mild-to-Moderate to Severe Asthma: Risk Factors and Patient Profiles from the NORDSTAR Cohort and Advances in Severe Asthma Management
Clinical Updatesasthma progressionbiologics

From Mild-to-Moderate to Severe Asthma: Risk Factors and Patient Profiles from the NORDSTAR Cohort and Advances in Severe Asthma Management

By MedXY|Sep 17, 2026

This review summarizes the progression risk from mild-to-moderate to severe asthma based on the NORDSTAR cohort and integrates emerging evidence on biologic therapies that improve severe asthma outcomes across diverse patient profiles.

Stratifying Risk for Further Retinal Intervention After Laser Retinopexy: The Impact of Cumulative Clinical Factors
newsvitreous hemorrhagerisk stratification

Stratifying Risk for Further Retinal Intervention After Laser Retinopexy: The Impact of Cumulative Clinical Factors

By MedXY|Sep 15, 2026

A novel, cumulative risk factor approach identifies patients at increased risk for additional retinal intervention after laser retinopexy for retinal tears, improving surveillance and management strategies.

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