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Medical news

8,171 articles

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Neurology

Reducing Recidivism in Traumatic Brain Injury Patients: Insights from the Re-entry Continuum for Brain Injury (RCBI) Trial

The RCBI trial demonstrates that targeted interventions beginning prior to release and continuing postrelease significantly reduce recidivism and improve coping and executive function in incarcerated men with traumatic brain injury.

Nov 2, 2026
Oncology

Enhanced Survival with Osimertinib and Savolitinib Combination in Advanced EGFR-Mutated NSCLC with MET Dysregulation Post-Osimertinib Progression

The phase 3 SAFFRON trial demonstrated that osimertinib combined with savolitinib significantly improves progression-free and overall survival versus platinum-pemetrexed chemotherapy in advanced EGFR-mutated NSCLC harboring MET overexpressi

Nov 2, 2026
Gastroenterology

Saroglitazar in Primary Biliary Cholangitis: Insights from a Phase 2b/3 Adaptive Randomized Trial

Saroglitazar, a dual PPAR α/γ agonist, demonstrated significant biochemical improvement and ALP normalization in primary biliary cholangitis patients refractory or intolerant to UDCA, with favorable safety over 52 weeks in a phase 2b/3 tria

Nov 2, 2026
Rehabilitation Medicine

Five-Year Outcomes of Arthroscopic Bankart Repair in Young Athletes With Minimal Glenoid Bone Loss: Recurrence, Return to Sport, and Risk Factors

Arthroscopic Bankart repair in young patients with minimal glenoid bone loss shows high clinical improvement and return to sport but a considerable recurrence rate, especially among contact sport athletes, highlighting the need for careful

Nov 1, 2026
Rehabilitation Medicine

Age-Related Differences Influence Outcomes of Long-Term Multimodal Stroke Intervention: Insights from the LAST-long Trial

The LAST-long trial investigated a community-based, individualized stroke intervention and found that age—but not frailty—significantly modifies its effectiveness, with older stroke survivors (≥80 years) experiencing less favorable outcomes

Nov 1, 2026
Gastroenterology

Linking Oral Health to Liver Cancer Risk: Insights from a Nationwide Swedish Cohort Study

A large Swedish cohort study reveals that dental diseases and tooth loss are associated with increased risk of primary liver cancer, highlighting the importance of oral health in systemic disease prevention.

Nov 1, 2026
Hematology-Oncology

Mitapivat in Sickle Cell Disease: A Promising Oral Therapy to Improve Hemolytic Anemia and Reduce Complications

The phase 3 RISE UP trial demonstrates that mitapivat significantly improves hemoglobin levels in sickle cell disease, offering a novel, well-tolerated oral treatment with potential to modify disease outcomes.

Nov 1, 2026
Pediatrics

Hydrocephalus: Advances in Treatment, Emerging Research, and Ongoing Challenges

Hydrocephalus is a multifaceted neurological disorder caused by cerebrospinal fluid imbalance. This review explores current surgical treatments, emerging technologies, molecular mechanisms, and challenges in managing hydrocephalus effective

Nov 1, 2026
Rheumatology

Isotype-Specific Autoantibody Remodeling in Antiphospholipid Syndrome via BAFF-APRIL Blockade

This study reveals that dual BAFF-APRIL blockade with telitacicept distinctly remodels pathogenic autoantibodies in antiphospholipid syndrome, showing differential effects across immunoglobulin isotypes and identifying marrow plasma-cell cl

Nov 1, 2026
Transplantation

Energetic Recovery and Myocardial Efficiency After Heart Transplantation: Insights from an Exploratory Study

This study explores myocardial external efficiency (MEE) and mitochondrial function in heart transplant recipients, revealing improved MEE at 6 months post-transplant associated with myocardial contractility and biomarkers, highlighting ene

Nov 1, 2026
Dermatology

Comparative Effectiveness and Safety of HMME-PDT Versus Pulsed Dye Laser in Treating Facial and Neck Port-Wine Stains: Insights from a Large Retrospective Study

A retrospective analysis reveals hematoporphyrin monomethyl ether-mediated photodynamic therapy (HMME-PDT) outperforms pulsed dye laser (PDL) in clearing facial and neck port-wine stains but with an increased risk of hyperpigmentation and s

Nov 1, 2026
Cardiology

Clinical Implications of Brachial-to-Radial Arterial Pressure Gradients in Critically Ill Patients on Vasoactive Therapy

A significant brachial-to-radial arterial pressure gradient occurs in nearly one-fifth of critically ill patients receiving vasoactive agents, correlating with higher vasoactive doses, greater illness severity, and increased ICU mortality.

Nov 1, 2026
Psychiatry

Hospital Discharge Prescriptions for Alcohol Use Disorder: Unveiling Key Predictors to Bridge the Treatment Gap

Despite proven benefits, medications for alcohol use disorder remain underprescribed at hospital discharge. This study identifies hospitalization and patient factors influencing new prescriptions, highlighting opportunities to enhance AUD t

Nov 1, 2026
Hematology-Oncology

Innovative Thrombin-Responsive AutoRegulated FVIII-Mimetic Antibodies for Safer Hemophilia A Therapy

A novel thrombin-cleavable FVIII-mimetic antibody enables dynamic, on-demand control of coagulation, reducing adverse thrombotic risk while maintaining efficacy in hemophilia A treatment.

Nov 1, 2026
Respiratory

Navigating Barriers to Lung Cancer Screening Follow-Up in Community Care: Insights from the ACCELL Trial

This study identifies key organizational, social, and individual determinants affecting lung cancer screening follow-up in community settings, highlighting strategies to improve adherence and optimize mortality benefits.

Nov 1, 2026
Ophthalmology

Recurrent Visual Field Progression in Glaucoma: Incidence, Risk Factors, and Clinical Implications

A cohort study identifies key risk factors such as faster baseline visual field loss, higher post-progression intraocular pressure, and older age that predict recurrence of visual field progression in glaucoma, emphasizing the need for pers

Nov 1, 2026
Otorhinolaryngology

Perception of Low-Frequency Musical Sound Quality in Hearing-Assistive Devices: Comparing Hearing Aids and Cochlear Implants

This study evaluates how users of hearing aids and cochlear implants perceive musical sound quality when low-frequency components are degraded, revealing significant differences in sensitivity relevant to patient counseling and device optim

Nov 1, 2026
General Surgery

Pancreatic Fistula and Intra-abdominal Fluid Collections After Distal Pancreatectomy: Incidence, Clinical Impact, and Management Strategies

This study analyzes the incidence and clinical consequences of pancreatic fistulas and intra-abdominal fluid collections following distal pancreatectomy, highlighting their management and the impact of surgical drain placement.

Nov 1, 2026
OB/GYN & Women's Health

Enhancing Follow-Up After Early Medical Abortion in New Zealand: Evidence from a Randomised Controlled Trial on Self-Assessment versus Serum bhCG Testing

A New Zealand RCT demonstrates that self-assessment with low sensitivity urine pregnancy tests after early medical abortion improves complete follow-up and successful abortion rates compared to serum bhCG testing, supporting safer, equitabl

Nov 1, 2026
Gastroenterology

Miricorilant in Metabolic Dysfunction-Associated Steatohepatitis: Promising Phase 1b Results Highlight Intermittent Dosing Strategy

This phase 1b study of miricorilant, a selective glucocorticoid receptor modulator, shows significant reductions in liver fat and improvements in liver health markers in patients with presumed metabolic dysfunction-associated steatohepatiti

Nov 1, 2026
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  4. 04Cardiology

    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

  5. 05General Surgery

    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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