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Routine Ultrasound Screening for Large-for-Gestational-Age Fetuses at Term: Balancing Diagnostic Limitations and Intervention Risks
newslarge-for-gestational-ageobstetric intervention

Routine Ultrasound Screening for Large-for-Gestational-Age Fetuses at Term: Balancing Diagnostic Limitations and Intervention Risks

By MedXY|Sep 8, 2026

Routine third-trimester ultrasound screening for suspected large-for-gestational-age fetuses shows limited accuracy, leads to increased obstetric interventions, and does not improve neonatal outcomes, suggesting a need for more individualiz

Sustained Reduction of Severe Maternal Morbidity and Racial Disparities Through a Statewide Perinatal Quality Collaborative
newsracial disparities

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news6629 articlesCardiology1375 articlesClinical Updates1288 articlesOncology1139 articlesDiabetes & Endocrinology842 articlesNeurology820 articlesPublic Health595 articlesGastroenterology572 articles
Hypertension

Sustained Reduction of Severe Maternal Morbidity and Racial Disparities Through a Statewide Perinatal Quality Collaborative

By MedXY|Sep 8, 2026

A Louisiana statewide perinatal quality collaborative significantly reduced severe maternal morbidity related to hemorrhage and hypertension, sustained improvements across initiatives, and narrowed racial disparities, demonstrating durable

Evaluating Neurodevelopmental Outcomes Following Intrapartum Azithromycin Administration in Neonates with Birth Asphyxia: Insights from the A-PLUS Follow-Up Study
newsbirth asphyxiaintrapartum antibiotic

Evaluating Neurodevelopmental Outcomes Following Intrapartum Azithromycin Administration in Neonates with Birth Asphyxia: Insights from the A-PLUS Follow-Up Study

By MedXY|Sep 8, 2026

A multicountry follow-up study found no significant improvement in neurodevelopmental outcomes at two years in infants with birth asphyxia whose mothers received a single 2 g oral dose of azithromycin during labor versus placebo.

Early Detection of Cerebral Small Vessel Disease: Diffusion MRI Reveals a Decade-Long Preclinical Phase Before White Matter Hyperintensities
Neurologycerebral small vessel diseasediffusion MRI

Early Detection of Cerebral Small Vessel Disease: Diffusion MRI Reveals a Decade-Long Preclinical Phase Before White Matter Hyperintensities

By MedXY|Sep 8, 2026

Diffusion MRI detects microstructural brain changes up to 16 years before white matter hyperintensities appear, offering a valuable early window for cerebral small vessel disease intervention and improved risk stratification.

Social Determinants of Health in Early to Mid-Adulthood and Risk of Early-Onset Stroke: A Comprehensive Review
Clinical Updateshealth disparitiesepidemiology

Social Determinants of Health in Early to Mid-Adulthood and Risk of Early-Onset Stroke: A Comprehensive Review

By MedXY|Sep 8, 2026

Accumulating evidence underscores how adverse social determinants of health (SDOH) from early adulthood heighten the risk of early-onset stroke, with dose-dependent effects and disparities by race and sex.

Gestational Changes in Antiseizure Medication Concentrations and the Impact of Polytherapy: Insights from a Prospective Multicenter Cohort Study in China
Clinical Updatespolytherapylamotrigine

Gestational Changes in Antiseizure Medication Concentrations and the Impact of Polytherapy: Insights from a Prospective Multicenter Cohort Study in China

By MedXY|Sep 8, 2026

Pregnancy significantly reduces antiseizure medication concentrations, with lamotrigine showing the greatest decline. Polytherapy and body weight modulate these changes, underscoring the importance of individualized therapeutic drug monitor

Immigration Status and Acute Stroke ICU Care: Insights from Ontario’s Population-Based Study
Critical Carehealth disparitiesICU care

Immigration Status and Acute Stroke ICU Care: Insights from Ontario’s Population-Based Study

By MedXY|Sep 8, 2026

This retrospective cohort study explores how immigration status influences ICU admission rates and length of stay among ischemic stroke patients in Ontario, revealing longer ICU stays for immigrants despite similar admission rates compared

Gardnerella Enrichment in the Vaginal Microbiome of Women with Gestational Diabetes Mellitus Is Associated with Lower Fetal Birthweight Percentiles
Diabetes & EndocrinologyGestational diabetes mellitusTăng trưởng thai nhi

Gardnerella Enrichment in the Vaginal Microbiome of Women with Gestational Diabetes Mellitus Is Associated with Lower Fetal Birthweight Percentiles

By MedXY|Sep 8, 2026

This study reveals that gestational diabetes alters vaginal microbiota, increasing Gardnerella abundance, which correlates with maternal glucose levels and lower fetal birthweight percentiles.

Improved Glycaemic Control and Vascular Outcomes After MiniMed 780G Usage in Older Adults with Type 1 Diabetes: A Randomised Controlled Trial
Diabetes & Endocrinologyolder adultstype 1 diabetes

Improved Glycaemic Control and Vascular Outcomes After MiniMed 780G Usage in Older Adults with Type 1 Diabetes: A Randomised Controlled Trial

By MedXY|Sep 8, 2026

This study demonstrates that using the MiniMed 780G hybrid closed-loop system significantly improves glycaemic management and shows a trend toward better microvascular function in adults aged 65 and above with type 1 diabetes, without incre

Cushing’s Syndrome in the Elderly: Diagnostic and Therapeutic Nuances in an Aging Population
Diabetes & EndocrinologyCushing's SyndromeHypercortisolism

Cushing’s Syndrome in the Elderly: Diagnostic and Therapeutic Nuances in an Aging Population

By MedXY|Sep 8, 2026

Cushing’s syndrome in older adults requires a tailored diagnostic approach and individualized management that prioritizes functional status and quality of life over chronological age, accounting for atypical presentations and comorbidities.

Harnessing Multidomain Baseline Metrics to Predict Attrition in Diabetic Foot Ulcer Offloading Trials
Diabetes & Endocrinologyoffloading devicesattrition prediction

Harnessing Multidomain Baseline Metrics to Predict Attrition in Diabetic Foot Ulcer Offloading Trials

By MedXY|Sep 8, 2026

Baseline clinical, functional, and psychosocial metrics predict participant attrition in diabetic foot ulcer offloading device trials; integration via risk visualization enhances retention strategies and highlights technology benefits.

Preserved Endogenous Insulin Production Significantly Reduces Diabetic Ketoacidosis Risk in Type 1 Diabetes
Diabetes & Endocrinologytype 1 diabetesEndogenous Insulin

Preserved Endogenous Insulin Production Significantly Reduces Diabetic Ketoacidosis Risk in Type 1 Diabetes

By MedXY|Sep 8, 2026

Detectable C-peptide levels indicating residual insulin production strongly correlate with lower diabetic ketoacidosis risk in type 1 diabetes, highlighting the importance of preserving beta-cell function for improved clinical outcomes.

Impact of Germline and Somatic DNMT3A Variants on Pulmonary Arterial Hypertension: A New Frontier in Biomarkers and Therapeutics
Cardiologypulmonary arterial hypertensionCHIP genes

Impact of Germline and Somatic DNMT3A Variants on Pulmonary Arterial Hypertension: A New Frontier in Biomarkers and Therapeutics

By MedXY|Sep 8, 2026

Germline and somatic variants in DNMT3A and other CHIP genes elevate pulmonary arterial hypertension risk, including connective tissue disease-associated forms, through pro-inflammatory pathways, highlighting novel biomarkers and therapeuti

Enhancing Diagnostic Accuracy in Stable Coronary Artery Disease: Impact of Adding CT-derived Fractional Flow Reserve (FFRct) – Insights from the FUSION Trial
CardiologyComputed tomographyinvasive coronary angiography

Enhancing Diagnostic Accuracy in Stable Coronary Artery Disease: Impact of Adding CT-derived Fractional Flow Reserve (FFRct) – Insights from the FUSION Trial

By MedXY|Sep 8, 2026

The FUSION randomized trial demonstrates that adding CT-derived FFR to coronary CTA significantly reduces unnecessary invasive angiographies without affecting clinical outcomes, cost, or quality of life in stable CAD patients with intermedi

Evaluating Vericiguat in Coronary Vasospasm: Insights from the ViVA Randomized Cross-Over Trial
CardiologyvericiguatCoronary Vasospasm

Evaluating Vericiguat in Coronary Vasospasm: Insights from the ViVA Randomized Cross-Over Trial

By MedXY|Sep 8, 2026

This article reviews the ViVA trial assessing vericiguat, an sGC stimulator, in angina patients with coronary vasospasm but no obstructive coronary artery disease. The study found no significant improvement in vasodilator function or angina

Tocilizumab Reduces Major Cardiovascular Events Risk in Giant Cell Arteritis: Insights from a Nationwide French Cohort
Cardiologytocilizumabcardiovascular risk

Tocilizumab Reduces Major Cardiovascular Events Risk in Giant Cell Arteritis: Insights from a Nationwide French Cohort

By MedXY|Sep 8, 2026

A nationwide observational study reveals tocilizumab use in giant cell arteritis significantly lowers major adverse cardiovascular events compared to methotrexate, highlighting its potential cardiovascular benefits beyond inflammation contr

Evolocumab Significantly Reduces Mortality in High-Risk Patients Without Prior Heart Attack or Stroke: Insights from the VESALIUS-CV Trial
CardiologyPCSK9 inhibitorEvolocumab

Evolocumab Significantly Reduces Mortality in High-Risk Patients Without Prior Heart Attack or Stroke: Insights from the VESALIUS-CV Trial

By MedXY|Sep 8, 2026

The VESALIUS-CV trial demonstrates that evolocumab lowers all-cause and cardiovascular mortality in patients with high cardiovascular risk but no prior myocardial infarction or stroke, highlighting its survival benefits in primary preventio

Safety and Effects of Gildeuretinol Acetate on Retinal Atrophic Lesions in Stargardt Disease: Insights from the TEASE-1 Randomized Clinical Trial
Clinical Updatesrandomized clinical trialStargardt disease

Safety and Effects of Gildeuretinol Acetate on Retinal Atrophic Lesions in Stargardt Disease: Insights from the TEASE-1 Randomized Clinical Trial

By MedXY|Sep 7, 2026

This review synthesizes evidence from the TEASE-1 trial and related studies on gildeuretinol acetate, highlighting its safety profile and modest efficacy in slowing retinal atrophic lesion growth in Stargardt disease over 24 months.

Compartment-Specific Nodal Recurrence in Medullary Thyroid Cancer: Evaluating the Role of Contralateral Prophylactic Central Neck Dissection
newsCentral Neck DissectionRecurrence Patterns

Compartment-Specific Nodal Recurrence in Medullary Thyroid Cancer: Evaluating the Role of Contralateral Prophylactic Central Neck Dissection

By MedXY|Sep 7, 2026

This multicenter study assesses recurrence patterns in medullary thyroid cancer, finding ipsilateral neck sites are the most common recurrence locations, with limited evidence supporting routine contralateral prophylactic central neck disse

Protocol-Based Early Intensive Lipid Management Significantly Enhances LDL-C Target Achievement Post-Acute Coronary Syndrome: Insights from the BRIDGE Trial
CardiologyLDL-C TargetLipid-Lowering Therapy

Protocol-Based Early Intensive Lipid Management Significantly Enhances LDL-C Target Achievement Post-Acute Coronary Syndrome: Insights from the BRIDGE Trial

By MedXY|Sep 7, 2026

The BRIDGE trial demonstrates that protocol-driven early intensive lipid-lowering therapy significantly improves guideline-recommended LDL-C target attainment in acute coronary syndrome patients, fostering better cardiovascular risk control

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