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The clinical briefing

Medical news

8,171 articles

Latest updates

Diabetes & Endocrinology

Focal Congenital Hyperinsulinism: Insights Into Spontaneous Glycemic Improvement Before Surgical Intervention

A retrospective study reveals that a subset of infants with focal congenital hyperinsulinism experience spontaneous glycemic improvement prior to surgery, suggesting a potential for conservative management in selected cases.

Oct 26, 2026
Clinical Updates

Return to Competition and Career Sustainability After Primary ACL Reconstruction in Football: Insights from Nationwide and Long-Term Studies

This review synthesizes evidence on return to competition and career sustainability after ACL reconstruction in football, highlighting variable return rates by competitive level, persistent long-term participation challenges, and multifacto

Oct 26, 2026
Superintelligence

Predicting Walking Ability in Nontraumatic Spinal Cord Injury Using Machine Learning: A Novel Temporal Validation Study

A new machine learning model predicts post-rehabilitation walking ability in nontraumatic spinal cord injury patients with high accuracy, aiding early clinical decision-making and rehabilitation planning.

Oct 26, 2026
Dentistry

Decoding Fluoride Discourse on X During the 2024 US Presidential Election: Implications for Public Health Communication

Analysis of fluoride discussions on X highlights strong negative sentiment intertwined with political distrust, underscoring the need for nuanced patient communication about fluoride’s safety and benefits in a polarized environment.

Oct 26, 2026
Anesthesiology

Evaluating Cardiac Index-Guided Hemodynamic Therapy in High-Risk Abdominal Surgery: Insights from the PELICAN Trial

The PELICAN trial found that individualized cardiac index-guided intraoperative hemodynamic therapy did not reduce major postoperative complications compared to routine care in high-risk major abdominal surgery patients.

Oct 26, 2026
Neurology

Remote Aerobic Exercise Accelerates Recovery in Youth with Prolonged Concussion: Insights from the MSTEP Randomized Trial

A virtual aerobic exercise program significantly improves recovery speed and quality of life in youth with prolonged concussion, especially when initiated within three months of injury, outperforming stretching interventions.

Oct 26, 2026
news

Evaluating Reduced Versus Standard Dosing of Janus Kinase Inhibitors in Rheumatoid Arthritis: Insights from a Propensity Score-Matched Real-World Study

A real-world Japanese study finds comparable 24-month treatment persistence between reduced and standard dosing of JAK inhibitors in rheumatoid arthritis patients with preserved renal function, with dose considerations influenced by poor pr

Oct 26, 2026
Internal Medicine

Optimizing Early Mycophenolate Mofetil Dosing Post-Kidney Transplant: A Nomogram Integrating Triglycerides and Body Weight

A novel nomogram using pretransplant triglycerides and body weight shows promise to guide early mycophenolate mofetil dosing after kidney transplantation, potentially reducing drug overexposure before therapeutic drug monitoring is feasible

Oct 26, 2026
Dermatology

International Consensus on Low‑Dose Oral Minoxidil in Children: Practical, Pediatric‑Specific Guidance

An international expert consensus provides the first pediatric‑specific framework for low‑dose oral minoxidil (LDOM) in children aged 4–11 years: indications, dosing strategies, safety checks, monitoring, contraindications, and long‑term us

Oct 26, 2026
Plastic Surgery

Innovative Oncoplastic Breast Reconstruction: Efficacy and Versatility of J-Scar Mammaplasty

J-scar mammaplasty offers a safe, versatile level 2 oncoplastic technique with favorable aesthetic and oncologic outcomes, validated in a 157-patient study with low complication rates and high satisfaction.

Oct 26, 2026
Critical Care

Differential Ventilatory Strategies and Outcomes in Neurocritical Versus Non-Neurocritical Care Patients: Insights From the PRIME Database

A pooled analysis from the PRIME database reveals distinct ventilatory management patterns and ARDS incidence in neurocritical versus non-neurocritical patients, highlighting key associations between ventilator settings and outcomes.

Oct 26, 2026
Cardiology

Does Patient-Centered Communication by Physicians Facilitate Cardiometabolic Disease Self-management Among Community Health Center Patients? A Nationwide Study

This study examines how effective patient-centered communication by physicians at community health centers supports self-management behaviors in patients with cardiometabolic conditions.

Oct 26, 2026
Hematology-Oncology

Enhancing FLT3 Inhibitor Efficacy in FLT3-ITD AML Through Targeting Mitochondrial Complex I Subunit NDUFS2

Targeting the mitochondrial complex I subunit NDUFS2 enhances sensitivity to FLT3 inhibitors and overcomes drug resistance in acute myeloid leukemia with FLT3-ITD mutations, suggesting a promising therapeutic strategy.

Oct 26, 2026
Clinical Updates

Striving for Equity in Cystic Fibrosis Research: Perspectives from Black and Hispanic/Latino(a) Individuals with CF

This review explores barriers and facilitators influencing research participation among Black and Hispanic/Latino(a) individuals with cystic fibrosis (CF), highlighting systemic inequities, racialized experiences, and community-centered sol

Oct 26, 2026
news

Uncovering Novel Genetic Contributors to Usher Syndrome: Insights from Comprehensive Mouse Knockout Models

A large-scale phenotypic screen of 9,139 knockout mouse lines identified 18 candidate genes linked to retinal and hearing abnormalities, offering promising new targets for understanding and diagnosing Usher syndrome.

Oct 26, 2026
news

Enhancing Nasal Septal Perforation Repair: The Role of Contralateral Free Mucosal Grafting for Rapid Re-Epithelialization

Free mucosal grafting on the contralateral side during nasal septal perforation repair enhances healing, achieving over 90% anatomical closure with rapid re-epithelialization and improved nasal symptoms.

Oct 26, 2026
Gastroenterology

Unveiling the Microbiome Landscape of Anastomotic Leaks After Foregut Surgery: Implications for Management and Outcomes

This study explores how microbiome compositions differ in patients with foregut anastomotic leaks managed endoscopically versus surgically, highlighting nutrition and microbial patterns as key factors influencing healing.

Oct 26, 2026
Diabetes & Endocrinology

Unraveling the Complex Interplay of BMI and Inflammation on Assisted Reproductive Outcomes in PCOS Women

This study reveals bidirectional mediation between BMI and inflammatory markers affecting embryo quality and availability in PCOS women undergoing ART, highlighting BMI’s predominant role.

Oct 26, 2026
Neurology

Disparities in Utilization and Adherence to Antiamyloid Therapies in Alzheimer’s Disease and Mild Cognitive Impairment

This study reveals that younger, non-Hispanic White patients with fewer comorbidities and lower socioeconomic vulnerability are more likely to receive antiamyloid medications for Alzheimer’s, while higher comorbidity predicts lower initial

Oct 26, 2026
news

Optimizing Neck Radiation in Advanced Differentiated Thyroid Carcinoma: Balancing Locoregional Control and Toxicity through Field Reduction

This study demonstrates that reducing radiation fields in advanced differentiated thyroid carcinoma lowers toxicity without compromising locoregional tumor control, supporting personalized radiotherapy strategies.

Oct 26, 2026
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    How often should a couple have sex?

  4. 04Cardiology

    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

  5. 05General Surgery

    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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