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Unveiling the Role of snoRNA-Derived RNAs in Hematopoiesis and Acute Myeloid Leukemia Prognosis
Hematology-OncologyHematopoiesisacute myeloid leukemia

Unveiling the Role of snoRNA-Derived RNAs in Hematopoiesis and Acute Myeloid Leukemia Prognosis

By MedXY|Sep 9, 2026

This article explores the expression and functional impact of snoRNA-derived RNAs in healthy blood formation and acute myeloid leukemia, highlighting their potential as biomarkers and therapeutic targets.

Antifibrinolytic Agents Enhance Liver Regeneration and Reduce Posthepatectomy Liver Failure: Translational Insights from Mice to Humans

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news6629 articlesCardiology1375 articlesClinical Updates1288 articlesOncology1139 articlesDiabetes & Endocrinology842 articlesNeurology820 articlesPublic Health595 articlesGastroenterology572 articles
Gastroenterologyliver regeneration

Antifibrinolytic Agents Enhance Liver Regeneration and Reduce Posthepatectomy Liver Failure: Translational Insights from Mice to Humans

By MedXY|Sep 9, 2026

Pharmacological reduction of plasminogen via antifibrinolytic agents accelerates liver regeneration after surgery in mice and decreases posthepatectomy liver failure risk in patients, representing a promising therapeutic approach.

Targeting Retinoic Acid-Driven CD16hiCD177+ Neutrophils in Steroid-Resistant GI-GVHD: A Novel Therapeutic Avenue
Gastroenterologyneutrophils

Targeting Retinoic Acid-Driven CD16hiCD177+ Neutrophils in Steroid-Resistant GI-GVHD: A Novel Therapeutic Avenue

By MedXY|Sep 9, 2026

Retinoic acid-driven expansion of CD16hiCD177+ neutrophils mediates steroid-resistant gastrointestinal graft-versus-host disease (GI-GVHD). Inhibition of the retinoic acid receptor restores steroid sensitivity and improves outcomes in murin

Expiratory Pressure Alleviation in CPAP Therapy: Impact on Upper Airway Patency and Obstructive Sleep Apnea Control
newsCPAPobstructive sleep apnea

Expiratory Pressure Alleviation in CPAP Therapy: Impact on Upper Airway Patency and Obstructive Sleep Apnea Control

By MedXY|Sep 9, 2026

Expiratory pressure alleviation during CPAP treatment reduces upper airway patency, increases residual apnea severity, and necessitates higher therapeutic pressure in severe OSA patients, without affecting treatment adherence.

Optimizing Patient Expectations and Outcomes: Understanding Days Alive and Out of Hospital After Lung Transplantation
newslung transplantation

Optimizing Patient Expectations and Outcomes: Understanding Days Alive and Out of Hospital After Lung Transplantation

By MedXY|Sep 9, 2026

This study evaluates days alive and out of hospital (DAOH) around lung transplantation, identifying predictors of reduced DAOH in the first post-transplant year and providing insights for tailored patient counseling and care strategies.

Defining and Achieving Disease Stability in COPD: Insights from Phase 3 Trials
newsCOPDexacerbations

Defining and Achieving Disease Stability in COPD: Insights from Phase 3 Trials

By MedXY|Sep 9, 2026

This article explores disease stability as a key treatment target in COPD, analyzing major phase 3 trials that show stability predicts reduced exacerbations and mortality, supporting its use to guide therapy.

Reevaluating the Frequent Exacerbator Phenotype in Bronchiectasis: Insights from the EMBARC Registry
newsexacerbation riskbronchiectasis

Reevaluating the Frequent Exacerbator Phenotype in Bronchiectasis: Insights from the EMBARC Registry

By MedXY|Sep 9, 2026

Analysis of over 19,000 bronchiectasis patients across 30 countries reveals a graded risk increase for future exacerbations with each prior event, challenging the fixed threshold concept of frequent exacerbators and confirming consistency a

Cumulative Atopic Disease Burden and Keratoconus: Insights from Large-Scale Cross-Sectional and Longitudinal Analyses
Clinical Updatesepidemiologykeratoconus

Cumulative Atopic Disease Burden and Keratoconus: Insights from Large-Scale Cross-Sectional and Longitudinal Analyses

By MedXY|Sep 9, 2026

This review synthesizes evidence linking cumulative atopic diseases—including asthma, atopic dermatitis, and allergic rhinitis—to keratoconus risk, highlighting a dose-dependent association and the role of healthcare utilization in case asc

Sex-Specific Associations Between Adiposity and Dry Eye Disease: Insights from a Large UK Biobank Study
Diabetes & Endocrinologydry eye diseaseSex Differences

Sex-Specific Associations Between Adiposity and Dry Eye Disease: Insights from a Large UK Biobank Study

By MedXY|Sep 9, 2026

Central obesity in women and high overall body fat in men are linked to increased odds of dry eye disease, with distinct metabolic pathways implicated, based on a retrospective analysis of over 480,000 UK Biobank participants.

Event-Based Progression Detection in Glaucoma: Integrating OCT, OCT Angiography, and Visual Field Metrics
Clinical Updatesvisual fieldglaucoma

Event-Based Progression Detection in Glaucoma: Integrating OCT, OCT Angiography, and Visual Field Metrics

By MedXY|Sep 9, 2026

This review synthesizes recent evidence on event-based progression detection in glaucoma, highlighting that OCTA vessel density may identify progression earlier than structural OCT or visual field testing, with important implications for cl

Longitudinal Trajectories of 3-Dimensional Eye Shape and Pathological Sequelae in High Myopia: Implications for Personalized Surveillance
Clinical UpdatesMRIhigh myopia

Longitudinal Trajectories of 3-Dimensional Eye Shape and Pathological Sequelae in High Myopia: Implications for Personalized Surveillance

By MedXY|Sep 9, 2026

This review synthesizes longitudinal evidence on 3D eye shape remodeling in high myopia, linking distinct morphologic trajectories to sight-threatening outcomes and supporting individualized risk stratification beyond axial length alone.

Evaluating the True Impact of a Dedicated Research Year on Otolaryngology Residency Applicants’ Scholarly Output
newsMedical Educationotolaryngology

Evaluating the True Impact of a Dedicated Research Year on Otolaryngology Residency Applicants’ Scholarly Output

By MedXY|Sep 9, 2026

This article examines whether taking a dedicated research year increases meaningful scholarly output among 2025 otolaryngology residency applicants, highlighting that increases are mainly in unpublished and middle-author work rather than pu

Differentiating Persistent and Recurrent Dysphagia After Surgery for Cricopharyngeal Muscle Dysfunction with Zenker Diverticulum: Insights from the POuCH Study
General SurgeryDysphagia

Differentiating Persistent and Recurrent Dysphagia After Surgery for Cricopharyngeal Muscle Dysfunction with Zenker Diverticulum: Insights from the POuCH Study

By MedXY|Sep 9, 2026

The POuCH study clarifies outcomes of surgery for cricopharyngeal muscle dysfunction (CPMD) with Zenker diverticulum, distinguishing persistent from recurrent dysphagia via patient-reported EAT-10 scores, aiding clinical management of posto

Impact of Decompensated Cirrhosis on Cardiac Surgery Outcomes: Clinical and Economic Implications
Cardiologycardiac surgeryHealthcare Costs

Impact of Decompensated Cirrhosis on Cardiac Surgery Outcomes: Clinical and Economic Implications

By MedXY|Sep 9, 2026

Decompensated cirrhosis markedly elevates mortality, complications, and costs following cardiac surgery. Optimized risk models and tailored management are essential for improved patient outcomes.

Advancing Vascular Reconstruction in Adult Living Donor Liver Transplantation: Deep Left Hilar Pedicle Isolation with In Situ Umbilical Portion Dissection
Gastroenterologyliving donor liver transplantation

Advancing Vascular Reconstruction in Adult Living Donor Liver Transplantation: Deep Left Hilar Pedicle Isolation with In Situ Umbilical Portion Dissection

By MedXY|Sep 9, 2026

This article reviews a novel surgical technique for adult living donor liver transplantation that enhances vascular reconstruction, significantly reduces hepatic arterial thrombosis, and utilizes the umbilical portion as an autologous graft

Nonvascularized Rectus Fascia Allografts: A Novel Cross-Disciplinary Approach for Complex Abdominal and Thoracic Reconstruction
General SurgerySolid organ transplantationAllograft

Nonvascularized Rectus Fascia Allografts: A Novel Cross-Disciplinary Approach for Complex Abdominal and Thoracic Reconstruction

By MedXY|Sep 8, 2026

This study evaluates nonvascularized rectus fascia allotransplantation (NVRF-alloTx) as an effective, versatile reconstructive option in both solid organ transplant and non-transplant patients, demonstrating promising integration and functi

Evaluating Quality of Life and Recurrence in Recurrent Diverticulitis: A Prospective Multicenter Study Comparing Colectomy and Observation
GastroenterologyrecurrenceNghiên cứu quan sát

Evaluating Quality of Life and Recurrence in Recurrent Diverticulitis: A Prospective Multicenter Study Comparing Colectomy and Observation

By MedXY|Sep 8, 2026

This multicenter prospective study reveals that colectomy in recurrent sigmoid diverticulitis improves disease-specific quality of life and reduces 1-year recurrence compared to observation, informing surgical decision-making.

Feasibility and Diagnostic Performance of Cervical Screening at 6 and 12 Weeks Postnatal: Insights from a Paired-Sample Study
newsCervical screeningUrine self-sampling

Feasibility and Diagnostic Performance of Cervical Screening at 6 and 12 Weeks Postnatal: Insights from a Paired-Sample Study

By MedXY|Sep 8, 2026

This feasibility study compares cervical screening at 6 and 12 weeks postnatal, assessing uptake, test performance, and patient experience, revealing high concordance and supporting early postnatal screening with some limitations for urine

Validating the ICIQ-PPHSAQ: Enhancing Assessment of Perinatal Pelvic Floor Dysfunction in Clinical Practice
newsICIQ-PPHSAQpelvic health assessment

Validating the ICIQ-PPHSAQ: Enhancing Assessment of Perinatal Pelvic Floor Dysfunction in Clinical Practice

By MedXY|Sep 8, 2026

The ICIQ-PPHSAQ questionnaire demonstrates robust validity and reliability for assessing pelvic floor dysfunction symptoms and risk factors during the perinatal period, supporting its application in English pelvic health services.

Cardiovascular and Bone Health Outcomes After Oophorectomy in Postmenopausal Women Undergoing Benign Hysterectomy: Insights from a Population-Based Study
Cardiologycardiovascular riskhysterectomy

Cardiovascular and Bone Health Outcomes After Oophorectomy in Postmenopausal Women Undergoing Benign Hysterectomy: Insights from a Population-Based Study

By MedXY|Sep 8, 2026

This study evaluates cardiovascular and bone health outcomes after bilateral oophorectomy during benign hysterectomy in postmenopausal women, highlighting increased risk for cardiovascular predisposition but no rise in clinical cardiovascul

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