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8,171 articles

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Orthopedics

Return to Sport After ACL Reconstruction: Insights from a Nationwide Swedish Cohort of High-Activity Athletes

A Swedish registry-based study reveals that 62% of athletes with high preinjury activity levels return to similar sports within a year after ACL reconstruction, with factors such as sex, age, and psychological readiness affecting outcomes.

Oct 30, 2026
Orthopedics

Characterizing Quality of Life Profiles in Rehabilitation Patients Across Diagnoses: Insights from Latent Profile Analysis

A cross-sectional study used latent profile analysis to identify distinct quality of life outcome profiles in rehabilitation patients with traumatic brain injury, spinal cord injury, stroke, and limb injuries, highlighting heterogeneous pat

Oct 30, 2026
Dentistry

Prenatal Exposure to Phthalates and Bisphenols and Its Association with Hypomineralization of Second Primary Molars in Children

This study examines how prenatal exposure to endocrine-disrupting chemicals like phthalates and bisphenol A correlates with hypomineralized second primary molars (HSPM) in children, revealing sex-specific effects and emphasizing the impact

Oct 30, 2026
Allergy & Immunology

Povetacicept Shows Promising Interim Results in Phase 3 Trial for IgA Nephropathy

Interim analysis of a phase 3 trial demonstrates povetacicept’s efficacy in reducing proteinuria and pathological markers in IgA nephropathy, with a favorable safety profile.

Oct 30, 2026
Cardiology

Sirolimus-Coated Balloon Angioplasty in Femoropopliteal Artery Disease Without Tissue Loss: Promising Secondary Outcomes from the SirPAD Trial

This secondary analysis of the SirPAD trial shows that sirolimus-coated balloon angioplasty significantly reduces 1-year target-lesion revascularization rates compared to uncoated balloons in femoropopliteal artery disease patients without

Oct 30, 2026
Oncology

Rilvegostomig Plus Trastuzumab-Deruxtecan: A Promising Neoadjuvant Therapy in Early-Stage ERBB2-Negative Breast Cancer

The I-SPY2.2 trial evaluated rilvegostomig combined with trastuzumab-deruxtecan in high-risk ERBB2-negative early breast cancer, showing promising pathologic complete response rates in immune-positive tumors while reducing exposure to anthr

Oct 30, 2026
Orthopedics

Association of Posterolateral ACL Bundle Position with Osteochondritis Dissecans of the Lateral Femoral Condyle: A New Anatomical Insight

This study identifies a distinct, more horizontal posterolateral ACL bundle orientation associated with osteochondritis dissecans in the lateral femoral condyle, suggesting a potential anatomical factor influencing lesion pathogenesis and h

Oct 30, 2026
Rehabilitation Medicine

Enhancing Post-Stroke Dysphagia Rehabilitation: Impact of Bimodal Signal Biofeedback on the Supraglottic Swallowing Maneuver

A randomized controlled trial demonstrates that bimodal biofeedback using accelerometer and nasal airflow sensors significantly improves swallowing function in post-stroke dysphagia patients undergoing supraglottic swallowing training.

Oct 30, 2026
Dentistry

Dynamic Changes in Salivary Extracellular Vesicles Post Non-Surgical Periodontal Therapy: A Novel Window into Periodontitis Treatment Response

This study reveals that six months of non-surgical periodontal therapy significantly modulates host and microbial extracellular vesicles in saliva, highlighting their potential as non-invasive biomarkers for monitoring periodontitis treatme

Oct 30, 2026
Nephrology

Ravulizumab in IgA Nephropathy: Interim Phase 3 Trial Analysis and Translational Insights

Ravulizumab, a terminal complement C5 inhibitor, significantly reduces proteinuria in adults with IgA nephropathy, demonstrating safety and biomarker improvements in phase 2 and 3 trials, highlighting its therapeutic potential.

Oct 30, 2026
Ophthalmology

Noncombustible Nicotine or Tobacco Product Use After Smoking Cessation and Major Vision-Impairing Diseases: Evidence from a Nationwide Cohort Study and Clinical Implications

This review synthesizes current evidence on the association between switching from combustible cigarettes to noncombustible nicotine/tobacco products and the risk of major vision-impairing eye diseases, highlighting a nationwide Korean coho

Oct 29, 2026
Otorhinolaryngology

Advancing Inner Ear Imaging: A Synchrotron-Based Deep Learning Network Outperforms Expert Segmentation in Clinical CT Scans

A novel deep learning network trained on synchrotron imaging data automates accurate inner ear segmentation in clinical CT, surpassing expert performance and establishing a new standard for preoperative planning.

Oct 29, 2026
General Surgery

KRAS Mutations in Duodenal Lavage Fluid After Secretin Stimulation: A Novel Biomarker for Early Detection of Pancreatic Cancer

Emerging evidence demonstrates that KRAS mutation analysis in secretin-stimulated duodenal lavage fluid offers a minimally invasive and sensitive approach for early detection of resectable pancreatic ductal adenocarcinoma, outperforming tra

Oct 29, 2026
OB/GYN & Women's Health

Ensuring Lasting Impact: Strategies for Sustainable Implementation of Surgical Trials in Gynecologic Oncology

Surgical randomized trials in gynecologic oncology revolutionize treatment approaches, but sustainability beyond publication requires structured implementation, credentialing, and vigilant post-trial surveillance to maintain safety, equity,

Oct 29, 2026
Neurology

Determinants and Outcomes of Vessel Recanalization Following Acute Cervical Artery Dissection: Insights from an International Multicenter Cohort

This multicenter study reveals that nearly 60% of cervical artery dissection patients achieve complete vessel recanalization at 6 months. Older age, diabetes, smoking, and initial complete occlusion markedly reduce recanalization odds, with

Oct 29, 2026
Diabetes & Endocrinology

Predicting Type 2 Diabetes Remission and Relapse After Metabolic-Bariatric Surgery and Lifestyle Therapy: Insights from the ARMMS-T2D Study

The ARMMS-T2D study identifies key baseline factors predicting remission and relapse of type 2 diabetes after metabolic-bariatric surgery or intensive medical-lifestyle therapy, aiding personalized treatment decisions.

Oct 29, 2026
Rehabilitation Medicine

Mid-Term Outcomes of Combined Endoscopic Gluteus Medius/Minimus and Arthroscopic Labral Repair: A Propensity-Matched Analysis

This study evaluates five-year outcomes comparing combined endoscopic gluteal tendon and labral repairs versus isolated labral repair, showing comparable patient-reported outcomes and reoperation-free survival despite greater initial abduct

Oct 29, 2026
Rehabilitation Medicine

Community-Based Exercise and Chronic Pain Management in Spinal Cord Injury: Insights from a Pragmatic Randomized Controlled Trial

A pragmatic RCT suggests that exercise following spinal cord injury guidelines may reduce chronic pain intensity, with significant benefits observed in pain interference and coping strategies.

Oct 29, 2026
Dentistry

Evaluating AI Tools for Periodontal Disease Diagnosis: Insights from a Comparative Study of Large Language Models and Retrieval-Augmented Systems

This study compared 11 AI platforms, including large language models and retrieval-augmented systems, for diagnosing and managing periodontal diseases using clinical vignettes rated by expert periodontists.

Oct 29, 2026
HIV/AIDS

Once-Weekly Oral Islatravir-Lenacapavir: A New Milestone in HIV-1 Treatment Simplification

A phase 3 trial demonstrates that once-weekly oral islatravir-lenacapavir is as effective and safe as daily bictegravir-emtricitabine-tenofovir alafenamide in maintaining HIV-1 viral suppression, offering a promising option to improve adher

Oct 29, 2026
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    Precision Medicine for Long QT Syndrome Type 2: Lumacaftor Corrects Trafficking Defects and Shortens QT Interval

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    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

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