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A pilot double-blind RCT suggests that adding a single ultrasound-guided dextrose prolotherapy injection to therapeutic exercise moderately improves shoulder pain and function in adults with subacromial-subdeltoid bursitis.
This study reveals that successful peri-implantitis surgical therapy is associated with distinct microbial network patterns, specifically increased connectivity and centrality of commensal bacteria, informing future microbiome-targeted appr
The CONNECT trial demonstrates that continuous glucose monitoring (CGM) significantly improves glycemic control in adults with non-insulin-treated type 2 diabetes managed in primary care, reducing HbA1c levels and hyperglycemia risk without
Lonvoguran ziclumeran, an in vivo CRISPR-based single-dose gene-editing therapy, significantly reduces hereditary angioedema attacks and demonstrates a favorable safety profile, marking a transformative advance in treatment.
Early increases in serum ST2 and REG3α within the first week after haploidentical stem cell transplantation with post-transplant cyclophosphamide predict transplant outcomes, highlighting their potential as prognostic biomarkers.
In EGPA patients unresponsive to mepolizumab, switching to benralizumab improves lung function, reduces glucocorticoid use, and shows a favorable safety profile, suggesting its potential as an effective alternative treatment.
Lower systemic blood pressure, especially minimum values measured over 24 hours, is associated with accelerated retinal nerve fiber layer loss in primary open-angle glaucoma, highlighting the prognostic value of ambulatory BP monitoring.
Optical coherence tomography (OCT) otoscopy delivers rapid, quantitative imaging of the tympanic membrane, distinguishing normal and diseased ears, improving diagnostic accuracy, and allowing longitudinal monitoring of middle ear pathologie
This study evaluates how treatment for cholecystitis affects the timely resumption of cancer therapy, highlighting that half of cancer patients return to therapy within six weeks, with hematologic malignancies and drainage procedures linked
An international Delphi panel offers practical, evidence-informed recommendations for managing spontaneous intracranial hypotension with spinal longitudinal epidural CSF collections, clarifying peri-epidural blood patch practice, imaging ch
This study reveals significant hippocampal subfield volume reductions and white matter impairments in patients with congenital adrenal hyperplasia, highlighting sex-specific differences that could influence cognitive outcomes and treatment
This article explores how baseline aldosterone concentrations influence the efficacy and outcomes of mineralocorticoid receptor antagonists (MRAs) in heart failure patients, highlighting the need for tailored therapeutic approaches.
This study evaluated whether 4 weeks of unilateral isometric elbow flexion resistance training induce adaptations in human reticulospinal tract function, finding no significant changes despite strength gains, thus informing neurorehabilitat
This qualitative study explores Austrian physiotherapists’ perspectives on direct access, revealing existing informal practice, confidence levels, organizational barriers, and training needs critical for policy reforms.
This study evaluates outcomes of medication-related osteonecrosis of the jaw (MRONJ) treatments in 222 patients, highlighting the superiority of surgical interventions over conservative therapy, especially in osteoporosis-associated cases.
A randomized clinical trial demonstrates that adding intraoperative dobutamine to norepinephrine during surgical source control for septic shock significantly decreases postoperative acute kidney injury incidence and severity.
A large prospective cohort study found no evidence linking neonatal medical male circumcision with increased risk of autism spectrum disorder or autism-related traits in children, providing reassurance for families and clinicians.
Indexing donor kidney parenchymal volume by recipient BMI via routine ultrasound strongly predicts one-year kidney graft function, offering a practical surrogate for graft-recipient size matching.
A telehealth intervention improved sun-protective behaviors among children of melanoma survivors but did not sustain reductions in sunburn rates compared to education alone, highlighting the challenge of long-term melanoma prevention in hig
This article explores the expanding role of artificial intelligence in plastic surgery, detailing medical benefits, legal risks, and strategies for risk mitigation to protect patients and practitioners.
