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The DECISION trial demonstrated that discontinuation of low-dose digoxin in heart failure patients optimized on guideline therapy leads to increased heart failure events and clinical deterioration, supporting cautious withdrawal decisions.
This retrospective study reveals that psychological readiness, measured by ACL-RSI scores, significantly predicts return to sport in adolescent patients after patellar stabilization surgery, overshadowing demographic and surgical factors.
Aquatic plyometric exercises significantly improve pain, muscle strength, and quality of life in adolescents with patellofemoral pain syndrome, offering a safe and effective rehabilitation option.
An AI-generated panoramic dental imaging score correlates independently with diabetes, hypertension, ischemic heart disease, osteoporosis, and hyperlipidemia, supporting integrated medical-dental care.
This phase 3 trial shows garetosmab significantly reduces new heterotopic bone lesions and is generally well tolerated in adults with fibrodysplasia ossificans progressiva (FOP), an ultra-rare and disabling genetic disorder.
A concise, practice-focused summary of the 2026 AAP clinical report on adolescent oral health—what pediatric clinicians should screen for, prevent, and refer.
Enhanced lipolysis in synovial fibroblasts marks early pathogenic changes in individuals at risk for rheumatoid arthritis, indicating metabolic shifts precede clinical disease onset.
This article analyzes global liver transplantation disparities relative to cirrhosis and chronic liver disease burden, revealing unequal access dominated by high-income countries and highlighting the role of health system development in tra
The AMETHYST Phase 2 trial demonstrated that litifilimab significantly improves skin symptoms in cutaneous lupus erythematosus with a favorable safety profile, marking a potential new targeted treatment for this challenging condition.
Ultrasound demonstrates high accuracy and reproducibility in preoperative localization of lymphovenous anastomosis sites, outperforming existing methods and offering a robust tool for lymphedema surgery planning.
A large nationwide cohort study reveals that patients with hematological malignancies and other immunosuppressive conditions have significantly higher risks of ICU-acquired infections, while those with solid tumors do not show increased inc
Racial disparities in respiratory tract infection diagnoses partially explain lower antibiotic prescribing rates in non-White patients, highlighting the need for equitable clinical assessment and antibiotic stewardship.
This study identifies immunoglobulin heavy chain constant domain-derived peptides as promising TCR therapy targets in multiple myeloma, demonstrating selective cytotoxicity and potential to preserve humoral immunity.
This study reveals that clarithromycin modulates inflammatory cytokines in community-acquired pneumonia, identifying distinct immune endotypes that may guide personalized immunomodulatory therapy.
Higher Charlson Comorbidity Index scores correlate with worse 1-year visual acuity outcomes in macular edema secondary to retinal vein occlusion, highlighting the impact of systemic health on ocular prognosis.
This article analyzes perioperative patient-initiated communication in septorhinoplasty, highlighting common concerns and identifying factors linked to increased contact with clinical teams, providing insights to improve patient care qualit
This UK prospective study assesses pregnancy outcomes in women with preexisting cardiomyopathy, revealing generally favorable maternal and neonatal results with low cardiac complication rates and no maternal deaths.
This study reveals significant racial differences in atherosclerotic cardiovascular disease risk among women with PMOS, highlighting that social determinants of health influence these disparities, particularly among Black women.
The ICare-FASTER trial demonstrates that implementing point-of-care high-sensitivity cardiac troponin testing in emergency departments safely reduces patient length of stay by nearly 50 minutes without compromising 30-day cardiac safety out
This longitudinal study demonstrates a modest association between acetabular labral tears and cartilage loss in young high-impact athletes, highlighting the complexity of hip joint degeneration and the need for multifactorial prevention str
