Section
This review synthesizes evidence on paternal valproate exposure and offspring neurodevelopmental risks, highlighting recent large cohort data that challenge prior concerns of increased neurodevelopmental disorders or congenital malformation
African adults with type 2 diabetes who are lean exhibit distinct complication profiles characterized by higher retinopathy and stroke risk but lower hypertension and cardiovascular disease risk compared to their overweight/obese counterpar
Clonal hematopoiesis (CHIP) significantly associates with increased silent brain lesions and progressive cognitive decline in atrial fibrillation patients, highlighting a novel neurovascular risk factor with implications for patient managem
Clinicians face multifaceted challenges during surgical decision-making for patients with dementia, including difficulties in dementia recognition, reliance on caregivers, and lack of evidence-based guidelines, underscoring the need for imp
This article explores the complex challenges clinicians face in surgical decision-making for patients with dementia, highlighting issues with dementia identification, caregiver roles, and the influence of dementia on surgical outcomes.
This study reveals that the characteristics of carotid plaque calcifications on CTA scans correlate with stroke symptoms beyond traditional stenosis severity, offering improved risk stratification for carotid artery disease.
A post hoc analysis of the BRIDGE-TNK trial reveals that intravenous tenecteplase before endovascular thrombectomy significantly improves functional independence in acute large-vessel occlusion stroke patients with extensive baseline ischem
Paramagnetic rim lesions detected via MRI are associated with increased risk of disability progression independent of relapse activity and accelerated brain atrophy in multiple sclerosis, highlighting their role as prognostic biomarkers for
This randomized trial demonstrates that adding virtual reality-based vestibular rehabilitation to home exercises significantly improves symptom severity and dynamic postural control in vestibular migraine patients.
Between 2010 and 2023 in Denmark, meningioma incidence doubled while treatment rates remained steady. Extensive follow-up imaging was common but rarely altered management, highlighting opportunities for risk-adapted surveillance protocols.
This review synthesizes evidence on colchicine’s efficacy in secondary stroke prevention, emphasizing the impact of concomitant atherosclerosis on outcomes from the CONVINCE trial and meta-analyses.
Achieving a ≥50% reduction in LDL-C from baseline independently reduces recurrent cardiovascular events post-ischemic stroke, suggesting that combining relative and absolute LDL-C targets improves long-term outcomes.
Serum neurofilament light chain (sNfL) z-score dynamics enhance monitoring of treatment response in relapsing multiple sclerosis (RMS), providing complementary predictive value for disease activity beyond conventional clinical and MRI asses
This study characterizes clinical and genetic features, explores triggers, and identifies prognostic factors, including idebenone treatment and mitochondrial haplogroups, in patients with late-onset Leber Hereditary Optic Neuropathy.
Highlight Women with cerebral palsy (CP) have significantly lower rates of routine gynecologic preventive care—including Pap tests, mammograms, and ge
This nationwide Finnish cohort study reveals that gout increases ischemic stroke risk in atrial fibrillation patients, with urate-lowering therapy linked to reduced stroke incidence, underscoring gout’s potential role in stroke risk s
A prospective cohort study reveals that surgical or radiosurgical intervention for symptomatic cerebral cavernous malformations is linked with increased risks of severe functional impairment or death over long-term follow-up, underscoring t
Discovery of anti-CD320 autoantibodies links autoimmune vitamin B12 deficiency to idiopathic myelopathy, revealing a distinct clinical and radiographic profile with promising treatment implications.
A machine learning model using simple clinical tests within 72 hours poststroke accurately predicts 6-month upper-limb motor outcomes, aiding rehabilitation planning.
This review synthesizes recent evidence linking menopausal hormone therapy (MHT), particularly estrogen-only regimens, with decreased Alzheimer disease neuropathology and clinical dementia risk, highlighting biomarker correlations, clinical
