Section
This article reviews the efficacy and clinical role of GnRH antagonist combination therapies in managing symptomatic uterine leiomyomas during perimenopause, emphasizing rapid symptom control, safety, and improved quality of life.
This review synthesizes recent evidence linking menopausal hormone therapy (MHT), particularly estrogen-only regimens, with decreased Alzheimer disease neuropathology and clinical dementia risk, highlighting biomarker correlations, clinical
This study examines prepectoral direct-to-implant breast reconstruction, showing it reduces complication rates and total surgeries compared to two-stage reconstruction, despite increased minor aesthetic revisions. It supports DTI as a safe,
This prospective multicenter study demonstrates that cfDNA fetal risk screening accurately identifies autosomal recessive conditions in general-risk pregnancies with high specificity and improved positive predictive value compared to tradit
Chorioamnionitis, especially with funisitis, attenuates fetal heart rate responses to hypoxia during labor, increasing susceptibility to hypoxic-ischemic encephalopathy at milder levels of acidemia in term fetuses.
This article reviews the complex interplay between major depressive disorder during pregnancy and selective serotonin reuptake inhibitor treatment, highlighting the importance of prioritizing maternal mental health to optimize outcomes for
The SENTIX study demonstrates that sentinel lymph node biopsy preserves quality of life, reduces lymphoedema incidence, and lowers early postoperative complications compared to pelvic lymphadenectomy in early-stage cervical cancer patients.
This nonrandomized clinical trial demonstrates the surgical feasibility of fetoscopic spina bifida repair using a human umbilical cord meningeal patch, showing comparable perinatal outcomes to open repair while enabling vaginal delivery and
Emerging evidence suggests menopausal estrogen-only therapy post-hysterectomy may reduce breast cancer risk both in general and BRCA mutation populations. Shared decision-making is key when considering therapy and surgical options for benig
This study reveals that distinct gestational diabetes mellitus (GDM) subtypes confer increased risks of prediabetes, diabetes, metabolic syndrome, and cardiovascular disease 10-14 years postpartum, underscoring the need for tailored long-te
Persistent low-level hCG following gestational trophoblastic disease often resolves spontaneously. Key clinical and biochemical predictors can identify patients at higher risk for subsequent neoplasia, guiding optimal surveillance.
A 14-year follow-up of twins exposed prenatally to 17-OHPC shows no significant effects on mortality, cognition, or development, indicating its long-term safety in multiple pregnancies.
Intrapartum sonography improves assessment accuracy for fetal head position, attitude, and station during difficult labor, aiding clinical decisions and potentially reducing complications associated with digital examination limitations.
This review synthesizes current evidence on menopausal hormone therapy’s cost-effectiveness, highlighting findings from a 2026 Markov model analysis and contextualizing with pivotal studies on health outcomes and economic implications
A novel assessment tool objectively measures surgeon performance in robotic-assisted and laparoscopic hysterectomy, demonstrating strong correlation with clinical outcomes and enabling quality assurance in gynecologic surgery education and
A randomized controlled trial shows that adding electrical stimulation biofeedback to pelvic floor muscle training offers limited long-term anatomical improvement for postpartum pelvic organ prolapse but improves muscle strength without sig
HER2 expression in recurrent cervical cancer varies notably by histology and recurrence site, underscoring the importance of reassessment to guide HER2-targeted treatments effectively.
This study investigates how semaglutide exposure before and during pregnancy affects gestational weight gain and key pregnancy outcomes in women with overweight or obesity, highlighting increased risks that may stem from treatment discontin
This multicenter study reveals improved outcomes in fetal cardiomyopathy, highlights genetic underpinnings in one-third of cases, and identifies fetal hydrops and extracardiac anomalies as key prenatal risk factors for mortality.
A retrospective study validates tissue-preserving breast augmentation using 3D imaging and ultrasound, demonstrating enhanced stability, natural aesthetics, and low complication rates.
