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The OPAL phase 2 trial compared neoadjuvant niraparib to standard platinum-taxane chemotherapy in newly diagnosed HR-deficient advanced ovarian cancer, showing inferior response rates with niraparib and a safety profile consistent with PARP
This qualitative study explores patient and obstetric clinician perspectives on postpartum venous thromboembolism (VTE) risk communication and pharmacologic thromboprophylaxis, highlighting education gaps and the need for individualized ris
This analysis of the C-STICH trial compares high and low transvaginal cerclage, revealing similar pregnancy loss rates but a modest prolongation of gestation and fewer very preterm births with high cerclage.
This article examines validated minimally invasive prediction models combining ultrasound and biomarkers to identify women at high risk for intra-amniotic infection or early delivery in preterm labor, aiming to guide selective amniocentesis
This analysis of nearly 1.4 million U.S. gynecologic cancer cases reveals that racial/ethnic minorities, socially vulnerable communities, and women lacking geographic access to gynecologic oncologists face higher odds of late-stage cancer d
A novel single-port transabdominal hysteroscopic approach offers a minimally invasive solution for perforated intrauterine device (IUD) removal, minimizing patient morbidity and enhancing recovery compared to traditional multiport laparosco
This study delineates the significant recurrence risk of severe hypertensive disorders of pregnancy, especially early-onset cases, highlighting implications for patient counseling and management in subsequent pregnancies.
A comprehensive longitudinal study reveals that menopausal transition does not significantly alter thyroid function beyond normal aging effects in healthy women, clarifying the interplay between menopause and thyroid health.
This prospective multicenter study demonstrates that B-Lite lightweight breast implants offer high efficacy, exceptional patient and surgeon satisfaction, and a favorable safety profile up to five years post-implantation in primary breast a
This study evaluates ovarian tissue cryopreservation (OTC) feasibility in girls and young women post-hematopoietic stem cell transplantation (HSCT), demonstrating OTC as a potential fertility salvage option despite reduced ovarian reserve a
Highlight Women with cerebral palsy (CP) have significantly lower rates of routine gynecologic preventive care—including Pap tests, mammograms, and ge
This study assesses the predictive accuracy of the MSKCC CT-based model for residual disease after neoadjuvant chemotherapy in advanced ovarian cancer, showing limited discrimination that improves with optimized clinical parameters. CT find
A nationwide French study reveals that nearly half of maternal deaths due to venous thromboembolism are preventable, emphasizing the importance of ongoing risk assessment and appropriate thromboprophylaxis during pregnancy and postpartum.
The MIPI trial demonstrates that preemptive multidose ibuprofen substantially reduces pain during intrauterine device (IUD) insertion, highlighting a practical approach to enhance patient comfort and potentially increase IUD acceptability.
This qualitative study explores how couples jointly cope with endometriosis, revealing shared challenges and adaptive strategies that bolster relational resilience and psychological wellbeing.
Analysis of NHANES data reveals increasing anemia and iron deficiency anemia rates among nonpregnant U.S. women aged 20-45 from 1999 to 2023, with persistently high iron deficiency prevalence.
A comprehensive analysis reveals that New York State’s Safe Motherhood Initiative significantly improved maternal outcomes in postpartum hemorrhage, reducing severe morbidity and hysterectomies over 15 years.
This study demonstrates that fetal fraction amplification significantly improves cell-free DNA screening feasibility as early as 7 3/7 weeks gestation, maintaining high accuracy and low failure rates, potentially transforming early prenatal
This study quantifies health-related quality of life impacts associated with risk-reducing hysterectomy, with and without bilateral salpingo-oophorectomy, to aid counseling and economic evaluation in endometrial cancer prevention.
This study reveals that psychological stress, anxiety, PTSD, and military sexual trauma are linked to increased urinary incontinence severity and affect response to behavioral treatments among women veterans, underscoring the importance of
