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In a pooled U.S. pregnancy cohort, maternal PFAS concentrations were not associated with a higher prevalence of gestational diabetes, and fasting glucose findings were largely null.
In a single-center real-world cohort, survival with mirvetuximab soravtansine, trastuzumab deruxtecan, and tisotumab vedotin broadly mirrored pivotal trials, with no independent survival differences by age, race, or ethnicity after adjustme
Canadian research reveals individuals with cerebral palsy face significantly higher risks of severe maternal complications, preterm birth, and neonatal issues during pregnancy, highlighting the need for specialized perinatal care.
In HCHS/SOL, prior gestational diabetes was linked to a proinflammatory gut microbiome, adverse metabolite patterns, and higher future type 2 diabetes risk, suggesting a plausible microbiome-mediated pathway after pregnancy.
In a Danish multicenter cohort of adnexal masses, IOTA-based models outperformed RMI for routine triage. A 15% ADNEX threshold best balanced sensitivity and referral burden in non-tertiary care.
Study reveals specific inflammation and oxidative stress markers in early pregnancy urine predict distinct fetal growth restriction patterns, offering potential for early detection and intervention strategies.
Early pregnancy urinary oxylipins linked inflammatory and oxidative stress pathways to small-for-gestational-age birth, with distinct signatures for early- and late-onset growth restriction. Associations with large-for-gestational-age birth
Introduction and Context Despite being highly preventable, cervical cancer remains a significant health threat. The…
Study finds long-term TSH suppression in postmenopausal women with thyroid cancer correlates with poorer cardiovascular health, reduced quality of life, and increased osteoporosis risk compared to controls.
A nationwide study reveals that eclampsia patients face a 6.9-fold increased risk of cardiovascular disease readmission within the first year postpartum, with stroke risk nearly 13 times higher than normotensive patients. These findings und
A combined analysis of 704 women found that anterior-predominant and apical prolapse is the most common phenotype (67.2%) in women undergoing native tissue apical surgery. While symptomatic recurrence ranged from 0% to 29% across phenotype
New research reveals that longer latency between hypertensive disorder of pregnancy diagnosis and delivery correlates with subtle inflammatory and lipid changes in young mothers, suggesting subclinical cardiovascular risk elevation years af
A real-world study of 671 endometrial cancer patients reveals significant molecular heterogeneity. PTEN, ARID1A, and PIK3CA are the most prevalent biomarkers, while TP53 mutations and ERBB2 amplification cluster in advanced-stage and non-en
A cross-sectional study of 37 RCOG Green-Top Guidelines reveals that 24% lack Grade A recommendations, while those with highest-level evidence show limited consideration of health equity and generalisability in supporting studies, highlight
A randomized trial of 205 pregnant women with gestational diabetes found that adjunctive flash glucose monitoring did not improve time-in-range glucose measurements compared to standard self-monitoring. However, the device was associated wi
This review explores how polygenic risk scores and clinical factors like BMI and pregnancy history predict incident hypertension 2 to 7 years post-delivery, highlighting the dominance of modifiable risk factors over genetic predisposition.
This retrospective study challenges the assumption that prior radiation limits immunotherapy effectiveness in recurrent endometrial and cervical cancers, finding no significant difference in response rates or survival outcomes based on recu
A large UK Biobank cohort study of 121,017 postmenopausal women reveals that earlier menopause significantly increases risks of multimorbidity progression, with women experiencing premature menopause facing 32% higher risk of developing fir
Prospective cohort data from Switzerland reveal that elevated sFlt-1/PlGF ratios at term correlate with shorter time to spontaneous delivery in low-risk pregnancies, while PlGF declines and sFlt-1 rises from term to post-term. These finding
A prospective study evaluating at-home stool collection for gut microbiome research in gynecologic oncology demonstrates implementation feasibility with 61% patient enrollment. Provider engagement emerged as the strongest predictor of parti
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