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MedXY News/Diabetes & Endocrinology

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Diabetes & Endocrinology

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Diabetes & Endocrinology

Risk Factors and Management of Iatrogenic Hypercalcemia during Active Vitamin D Supplementation for Hypoparathyroidism Post-Total Thyroidectomy

Iatrogenic hypercalcemia complicates 14% of hypoparathyroidism cases post-total thyroidectomy, linked to low early postoperative parathyroid hormone and early vitamin D initiation. Careful supplementation and monitoring are vital in prevent

Aug 24, 2026
Cardiology

Parathyroidectomy Significantly Lowers Cardiovascular Risk in Primary Hyperparathyroidism: Insights from a Population-Wide Target Trial Emulation

This population-wide study demonstrates that parathyroidectomy in primary hyperparathyroidism reduces major adverse cardiovascular events risk, particularly in patients with higher serum calcium levels.

Aug 24, 2026
Diabetes & Endocrinology

Distinct Complication Patterns in Lean Versus Overweight African Adults with Type 2 Diabetes: Implications for Targeted Management

African adults with type 2 diabetes who are lean exhibit distinct complication profiles characterized by higher retinopathy and stroke risk but lower hypertension and cardiovascular disease risk compared to their overweight/obese counterpar

Aug 24, 2026Sign in to read
Diabetes & Endocrinology

Refining Diabetes Classification in East Asians: Harnessing Data-Driven Clusters for Precision Medicine

This article reviews data-driven diabetes subtypes in East Asians, highlighting unique pathological features, genetic influences, and complication risks, emphasizing personalized treatment strategies for optimized care.

Aug 24, 2026
Diabetes & Endocrinology

Racial, Ethnic, and Socioeconomic Disparities in Islet Autoantibody Patterns Among Individuals at Risk for Type 1 Diabetes

Islet autoantibody positivity varies significantly among racial and ethnic groups and is influenced by socioeconomic deprivation, implicating tailored screening and prevention strategies for equitable diabetes care.

Aug 24, 2026
Cardiology

Early Weight Loss in Impaired Glucose Tolerance Significantly Lowers Long-term Cardiovascular and Mortality Risks: Insights from the Da Qing Diabetes Prevention Study

Early weight loss after impaired glucose tolerance diagnosis is linked to markedly reduced long-term risk of cardiovascular events and death, underscoring the importance of early lifestyle interventions in prediabetes management.

Aug 24, 2026
Diabetes & Endocrinology

Gene-Lifestyle Synergy in Diabetic Retinopathy Development

This study reveals how genetic risk for diabetic retinopathy can be significantly mitigated by healthy lifestyle choices, emphasizing universal behavioral interventions for prevention.

Aug 23, 2026
Diabetes & Endocrinology

Optimizing Fertility and Pregnancy Outcomes in Women with Congenital Adrenal Hyperplasia

This article reviews challenges and management strategies for achieving pregnancy in women with 21-hydroxylase deficiency congenital adrenal hyperplasia, emphasizing hormonal normalization and individualized glucocorticoid therapy.

Aug 22, 2026
Diabetes & Endocrinology

Octreotide in the Management of Catecholamine-Secreting Pheochromocytomas and Paragangliomas: A Promising Adjunctive Therapy

Octreotide shows potential as an effective adjunctive therapy in catecholamine-secreting pheochromocytomas and paragangliomas, improving biochemical, hemodynamic, and metabolic parameters and supporting perioperative management.

Aug 22, 2026
Diabetes & Endocrinology

Gestational Diabetes Mellitus: Ethnic Variations in Recurrence and Long-Term Type 2 Diabetes Risk

This study highlights the high recurrence of gestational diabetes mellitus (GDM) and its strong association with future type 2 diabetes, particularly among Asian women, underscoring the need for ethnicity-specific prevention and screening s

Aug 22, 2026
Diabetes & Endocrinology

Durability of β-Cell Function After Cessation of Baricitinib Immunotherapy in New-Onset Type 1 Diabetes

Baricitinib treatment in recent-onset type 1 diabetes preserves β-cell function during therapy. However, this effect diminishes within a year after stopping treatment, highlighting the need for sustained immunotherapy for lasting benefit.

Aug 22, 2026
Diabetes & Endocrinology

Mazdutide: A Novel Dual Agonist Demonstrates Significant Weight Loss in Adults with Obesity or Overweight

Mazdutide, a once-weekly glucagon and GLP-1 receptor dual agonist, delivers clinically meaningful weight reduction in adults with obesity or overweight, with higher doses yielding superior outcomes and manageable safety profiles.

Aug 22, 2026
Cardiology

Unmasking Silent Heart Failure in Diabetes: Insights from the TARTAN-HF Trial

The TARTAN-HF trial demonstrated that targeted natriuretic peptide screening in high-risk diabetic patients uncovers a high prevalence of undiagnosed heart failure, mainly HFpEF, enabling earlier treatment initiation and improved clinical c

Aug 21, 2026Sign in to read
Cardiology

Semaglutide’s Impact on Inflammation and Cardiovascular Risk in Overweight Patients: Insights from the SELECT Trial

In the SELECT trial, semaglutide significantly lowered hsCRP levels and major cardiovascular events in patients with established atherosclerotic cardiovascular disease and overweight or obesity, suggesting inflammation reduction as a possib

Aug 21, 2026
Cardiology

suPAR as a Novel Marker for Residual Inflammatory Risk Beyond hs-CRP in Type 2 Diabetes with Coronary Artery Disease

In type 2 diabetes patients with coronary artery disease, suPAR levels remain unchanged despite treatment and independently predict adverse cardiovascular events beyond hs-CRP, highlighting suPAR’s potential in identifying treatment-r

Aug 21, 2026
Diabetes & Endocrinology

Age-Specific Excess Healthcare Burden of Diabetes: Beyond Traditional Complications

Diabetes significantly increases inpatient admissions and ED visits across all ages, driven increasingly by nontraditional complications. Age-specific risks reveal shifting patterns in healthcare utilization that call for tailored clinical

Aug 21, 2026
Diabetes & Endocrinology

Long-Term Fatigue in Differentiated Thyroid Cancer Survivors: Early Predictors and the Non-Impact of Thyrotropin Suppression

A nationwide prospective study identifies early fatigue and poor mental health as key predictors of long-term fatigue in differentiated thyroid cancer patients, while thyrotropin suppression shows no association with fatigue.

Aug 21, 2026
Diabetes & Endocrinology

Dulaglutide Versus Insulin in Adolescents With Thalassaemia-Induced Diabetes: Improving Glycaemic Control and Metabolic Health in a High-Risk Population

The DIADEMA trial demonstrates dulaglutide’s superiority over insulin in improving glycaemic variability, pancreatic function, and iron overload, without safety concerns, in adolescents with thalassaemia-induced diabetes.

Aug 21, 2026
Diabetes & Endocrinology

Menopausal Transition and Thyroid Function: Deciphering the Impact Beyond Aging in Midlife Women

A comprehensive longitudinal study reveals that menopausal transition does not significantly alter thyroid function beyond normal aging effects in healthy women, clarifying the interplay between menopause and thyroid health.

Aug 21, 2026
Diabetes & Endocrinology

Circulating miR-1-3p Precedes Adrenarche and Modulates Adrenocortical Steroidogenesis via Protein Kinase C Signaling

Circulating miR-1-3p levels rise before clinical signs of adrenarche and regulate adrenal steroid hormone production through protein kinase C signaling pathways.

Aug 21, 2026
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