Section
This review synthesizes evidence on the prevalence and prognostic value of right ventricular dysfunction in ATTR-CM and the therapeutic impact of vutrisiran on RV function from the HELIOS-B trial, underscoring RV free wall strain as a key b
The TRANSPORT trial showed no superiority of liberal versus restrictive RBC transfusion in septic shock patients with cancer, highlighting no mortality benefit and increased thrombotic events with liberal strategy, underscoring the need for
This review synthesizes a meta-analysis of relapse trajectories following paliperidone discontinuation with evidence on antipsychotic maintenance and discontinuation strategies, highlighting individualized risk stratification and clinical i
Technology-guided diet counseling training using the Nutri platform improves resident physicians’ attitudes, self-efficacy, and intention to discuss diet, facilitating shared decision making in routine primary care.
This review examines emerging evidence on AI-assisted LC-OCT as a noninvasive, accurate tool for detecting subclinical basal cell carcinoma in high-risk patients, highlighting diagnostic performance, subtype classification, and translationa
Post-MI adherence to diverse healthy dietary patterns is consistently linked to reduced mortality and cardiovascular events, underscoring the importance of diet quality in secondary prevention among MI survivors.
This review examines informed consent patterns and predictors in an international ICU trial on stress ulcer prophylaxis, highlighting the shift to deferred consent, pandemic influences, and implications for critical care research ethics.
This review synthesizes key epidemiologic evidence linking transfusion-related allergic reactions with alpha-gal syndrome (AGS), revealing significant risk in blood type O recipients of B or AB plasma/platelets in AGS-endemic regions.
Carvedilol demonstrates superior effectiveness over nadolol and propranolol in reducing portal hypertension and preventing cirrhosis decompensation events, with emerging evidence supporting its preferential use in both compensated and decom
Ophthalmic herpes infections generally do not increase overall malignancy risk, but herpes zoster ophthalmicus (HZO) elevates cancer risk in patients with immune dysregulation, underscoring the need for tailored oncologic vigilance.
This review elucidates the prognostic significance of HARM and GLOS as imaging biomarkers after mechanical thrombectomy, highlighting their associations with early neurological outcomes and infarct progression.
This review synthesizes real-world data from the DESCAR-T registry on CAR T-cell therapy response kinetics in large B-cell lymphoma, highlighting the prognostic impact of early response patterns and factors influencing conversion from parti
This review synthesizes evidence linking neighborhood socioeconomic deprivation with increased Breslow thickness and delayed surgical management in head and neck cutaneous melanoma, highlighting potential mechanisms and clinical implication
This review synthesizes evidence on home-based cognitive training feasibility, adherence, and patient experiences in gynecologic cancer survivors with CRCI, highlighting clinical implications and directions for optimized intervention design
This review synthesizes evidence on deep learning models for assessing technical skills and error detection in robotic-assisted vaginal cuff closure, emphasizing objective surgical skill evaluation, model accuracy, and implications for surg
This review synthesizes evidence on paternal valproate exposure and offspring neurodevelopmental risks, highlighting recent large cohort data that challenge prior concerns of increased neurodevelopmental disorders or congenital malformation
Clonal hematopoiesis (CHIP) significantly associates with increased silent brain lesions and progressive cognitive decline in atrial fibrillation patients, highlighting a novel neurovascular risk factor with implications for patient managem
This review synthesizes evidence on health status impairments in long-term TKI-treated CML survivors relative to BMT survivors and non-cancer controls, emphasizing rates of functional impairment, activity limitation, frailty, and quality of
This review synthesizes recent randomized clinical trials and real-world studies confirming the safety and efficacy of highly aspherical lenslets (HAL) spectacle lenses in slowing myopia progression among children, emphasizing comparative e
Histidine-rich glycoprotein (HRG) directly modulates platelet adhesion and aggregation by binding platelet receptors GPIbα and GPIIb/IIIa, competing with key ligands VWF and fibrinogen, thus attenuating thrombus formation; reduced HRG in se
