Section
This study demonstrates that experimental fluoride gels reduce enamel mineral loss from citric acid erosion but not hydrochloric acid, highlighting acid type as a critical factor in designing effective anti-erosive dental treatments.
This review critically examines the SAVE-ICU trial assessing isoflurane inhaled sedation versus intravenous sedation in mechanically ventilated adults with acute hypoxemic respiratory failure, highlighting implications for clinical practice
This review synthesizes evidence evaluating the Epic Pediatric Sepsis Early Detection Model (PESM), highlighting its low sensitivity for early sepsis identification, disparities in performance across demographics, and implications for clini
A newly developed weighted flare scoring system in SLE accurately predicts organ damage accumulation, outperforming traditional flare classifications and informing treat-to-target strategies.
Prioritized lung transplant recipients exhibit higher severe PGD rates and mortality, yet prioritization itself is not an independent PGD predictor; pre-transplant ECMO is the primary risk factor.
Lichen planus is linked to increased risks of oral and genital cancers, with risks correlating to lesion sites. Despite low absolute risks, vigilant cancer surveillance in LP patients is warranted.
This multicenter randomized study confirms that Belotero Intense with lidocaine is a safe and effective hyaluronic acid filler for lip augmentation, showing noninferiority to Restylane Silk and sustained improvement up to 48 weeks.
This review synthesizes evidence on GLP-1 receptor agonist initiation impacting psychiatric hospitalisation and emergency visits in adults with schizophrenia and type 2 diabetes, highlighting metabolic and psychiatric interplay and therapeu
New evidence suggests lower urine output thresholds than current standards better predict acute kidney injury, chronic kidney disease, and mortality in critically ill patients, urging redefinition of oliguria parameters in AKI diagnostics.
Mitochondrial transfer from pediatric AML blasts to macrophages via tunneling nanotubes induces metabolic and immunosuppressive reprogramming, impairing anti-leukemic immune responses and supporting chemoresistance, revealing potential targ
This review synthesizes current evidence on high-frequency chest wall oscillation (HFCWO) for airway clearance in acute respiratory failure with bronchial hypersecretion, highlighting recent RCT findings, mechanistic insights, and future re
Corrective lens spending affects nearly 20% of the US population, with half paying fully out-of-pocket, highlighting substantial financial burdens and access barriers. Evidence from clinical trials and epidemiologic studies underscores cost
Precision phenotyping using audiometric pure-tone averages enhances genetic variant detection for sensorineural hearing loss compared to diagnostic coding, offering improved heritability estimates and risk prediction to advance hearing heal
This review synthesizes evidence from large cohort studies and meta-analyses highlighting bariatric surgery’s association with reduced risks of many obesity-related cancers, consistent across age and sex. Mechanistic insights and impl
A robust multivariable model predicts anal incontinence risk one year postpartum in primiparous women with second- to fourth-degree perineal tears, aiding personalized clinical care.
A study in asymptomatic first-degree relatives of Crohn’s disease patients defines preclinical stages using faecal calprotectin, offering a targeted screening approach to enrich prevention trial cohorts.
This study evaluates the association between early pregnancy use of anti-CGRP monoclonal antibodies or propranolol and spontaneous abortion risk, finding increased risk with anti-CGRP mAbs but not with propranolol.
This study finds that waist circumference is a better and more practical tool than traditional cardiometabolic indices for detecting hypogonadism in men with Klinefelter Syndrome, enhancing clinical assessment beyond age alone.
A subcutaneous furosemide minipump-enabled early discharge strategy improves days alive and out of hospital in heart failure patients, reducing inpatient stay without increasing serious adverse events significantly.
High-grade percutaneous medial collateral ligament (MCL) pie-crusting during medial meniscus posterior root tear repair yields improved surgical visualization without causing clinically meaningful postoperative valgus instability.
