Section
Quantitative CT imaging offers valuable prognostic information and helps assess treatment response in patients with progressive pulmonary fibrosis, supporting better clinical trial outcomes and therapeutic decisions.
This study validates the prognostic accuracy of the 15-gene expression profiling (15-GEP) and PRAME assay in uveal melanoma patients irrespective of confirmatory cytopathology, supporting its use in clinical management when cytopathology is
This review evaluates evidence linking perioperative cannabis use to prolonged opioid use and functional outcomes in head and neck cancer patients undergoing free flap reconstruction, emphasizing implications for pain management.
Federal executive orders restricting DEI initiatives pose significant challenges to academic surgery’s workforce diversity, research integrity, and editorial freedom. Adaptive strategies integrating equity into existing quality and sa
This study reveals extensive molecular changes in amniotic fluid proteomes during the execution phase of human labor, highlighting distinct biological processes linked to cervical dilatation stages at term.
This study demonstrates that nucleos(t)ide analogue therapy significantly reduces cirrhosis and hepatocellular carcinoma risk in specific HBeAg-positive chronic HBV infection phases beyond current EASL 2025 treatment indications.
This review synthesizes global dementia incidence from the COSMIC consortium, highlighting variations by age, sex, and economic regions, with implications for prevention and resource planning, informed by recent meta-analyses on risk factor
Recent advances in diabetes care have reduced mortality risk in type 1 diabetes, yet females with type 1 diabetes continue to experience disproportionately higher relative mortality compared to males.
This study establishes transthyretin amyloid cardiomyopathy-specific mitral regurgitation thresholds, revealing lower severity cutoffs than guidelines and enhancing mortality and heart failure hospitalization risk prediction.
This review synthesizes phase 2 trial data supporting neoadjuvant stereotactic ablative radiotherapy for RCC with IVC tumor thrombus, highlighting improved recurrence-free survival, acceptable safety, and biomarker insights that underscore
A randomized trial found that individualized swimming combined with education improves disability in chronic low back pain patients more than education alone, with benefits evident at 8 weeks but not sustained at 1 year.
This article explores the strategic use of patient-centered outcomes data to foster continuous learning and improve rehabilitation care at both individual and system levels, addressing challenges and proposing solutions for effective implem
This study evaluates the accuracy and reliability of intraoral ultrasonography to measure gingival sulcus depth compared to traditional clinical probing, demonstrating high agreement and potential as a non-invasive diagnostic tool in dental
This phase 2b trial demonstrates that oral icotrokinra, targeting the interleukin-23 receptor, significantly improves clinical outcomes in moderate to severe ulcerative colitis compared to placebo.
Pegylated interferon-alpha after nucleos(t)ide analog withdrawal induces coordinated expansion of regulatory B cells and contraction of HBV-specific T cells, impacting viral control and hepatic inflammation in HBeAg-negative chronic hepatit
Nationwide analyses show that epilepsy markedly increases the risk of young-onset dementia (YOD) before age 65, with persistent associations even years after epilepsy diagnosis, underscoring the need for YOD risk assessment in epilepsy care
This Phase II trial demonstrates that HRS-7535, an oral small-molecule GLP-1 receptor agonist, significantly improves glycaemic control and is well-tolerated in type 2 diabetes patients inadequately controlled with metformin and SGLT2 inhib
The 2026 EAPCI–ACVC consensus refines use of temporary mechanical circulatory support in acute myocardial infarction with cardiogenic shock, emphasizing phenotype-driven device selection, SCAI/SHARC staging, multidisciplinary shock teams an
This study explores how physical activity influences lung and kidney function in COVID-19 survivors, showing active survivors had better lung outcomes but no significant kidney benefits, highlighting the importance of tailored rehabilitatio
A behavioural mapping study reveals inpatient inactivity and isolation are common across acute and rehabilitation wards, highlighting the need for systemic changes to hospital routines and environments to boost physical, cognitive, and soci
