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This RCT demonstrates that combining multidimensional functional training with inspiratory muscle training and chest physiotherapy improves weaning success, muscle strength, functional independence, pain reduction, and ICU stay following em
A province-wide quality improvement initiative in Ontario implemented a web-based Family Satisfaction in ICU (FS-ICU) survey across adult level 3 ICUs, revealing high satisfaction scores yet highlighting challenges in participation and comp
The 2026 EAPCI–ACVC consensus refines use of temporary mechanical circulatory support in acute myocardial infarction with cardiogenic shock, emphasizing phenotype-driven device selection, SCAI/SHARC staging, multidisciplinary shock teams an
This review critically examines the SAVE-ICU trial assessing isoflurane inhaled sedation versus intravenous sedation in mechanically ventilated adults with acute hypoxemic respiratory failure, highlighting implications for clinical practice
This review synthesizes evidence evaluating the Epic Pediatric Sepsis Early Detection Model (PESM), highlighting its low sensitivity for early sepsis identification, disparities in performance across demographics, and implications for clini
Prioritized lung transplant recipients exhibit higher severe PGD rates and mortality, yet prioritization itself is not an independent PGD predictor; pre-transplant ECMO is the primary risk factor.
New evidence suggests lower urine output thresholds than current standards better predict acute kidney injury, chronic kidney disease, and mortality in critically ill patients, urging redefinition of oliguria parameters in AKI diagnostics.
This review synthesizes current evidence on high-frequency chest wall oscillation (HFCWO) for airway clearance in acute respiratory failure with bronchial hypersecretion, highlighting recent RCT findings, mechanistic insights, and future re
This article explores findings from a multicenter study evaluating the impact of cardiopulmonary resuscitation ventilation rates on survival in pediatric intensive care, identifying age-specific ventilation targets linked to improved outcom
This study confirms the K-Force grip dynamometer as a responsive tool to detect short-term changes in handgrip strength in ICU-acquired weakness patients, supporting its clinical utility in critical care rehabilitation.
Higher cumulative inotropic exposure during VA ECMO support in cardiogenic shock is associated with increased risk of ECMO weaning failure, mortality, arrhythmias, and delayed lactate clearance, highlighting the need for prospective trials
A 34-day-old male infant with serum sodium >200 mmol/L from accidental salt ingestion was successfully treated with peritoneal dialysis, leading to full recovery.
This study reveals how diabetes and ASCVD alter the link between soluble TNF receptor 1 levels and 90-day sepsis mortality, informing biomarker-guided risk assessment and understanding of sepsis pathobiology.
A large randomized trial finds no difference in 90-day days alive and out of hospital between early vasopressors with restricted fluids versus higher fluids with delayed vasopressors in septic shock, though pulmonary edema was less frequent
This study validates the Patient Dignity Inventory (PDI) as a reliable tool to assess dignity-related distress over 12 months in acute respiratory failure survivors, supporting dignity-centered interventions to improve long-term psychosocia
Ondansetron, a 5-HT3 antagonist, reduces respiratory drive in ARDS patients on mechanical ventilation by attenuating pulmonary C-fiber mediated stimulation, potentially lessening lung injury and improving oxygenation.
Standardizing care for neonates with transient tachypnea significantly reduced NICU length of stay and medical interventions without compromising safety or breastfeeding rates.
Non-Hispanic Black and Hispanic ICU survivors exhibit higher rates of physical impairment at discharge and increased healthcare utilization within one year, highlighting critical racial and ethnic disparities in post-ICU recovery.
This review synthesizes evidence on how individual patient characteristics modify the comparative effects of cefepime versus piperacillin-tazobactam on acute kidney injury and neurologic outcomes in adults hospitalized with acute infection.
This study identifies higher pharmacist-to-patient ratios and interruptions in comprehensive medication management as key contributors to increased mortality among ICU patients, highlighting the need for optimized pharmacist staffing in cri
