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MedXY News/Ophthalmology

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Ophthalmology

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Diabetes & Endocrinology

Real-World Eligibility of Diabetic Macular Edema Patients for Anti-VEGF Trials: Implications for Clinical Practice and Health Equity

A significant proportion of real-world diabetic macular edema patients are excluded from clinical trials of anti-VEGF therapy due to stringent systemic criteria, disproportionately affecting racial minorities. This study highlights the need

Sep 10, 2026
Clinical Updates

Cumulative Atopic Disease Burden and Keratoconus: Insights from Large-Scale Cross-Sectional and Longitudinal Analyses

This review synthesizes evidence linking cumulative atopic diseases—including asthma, atopic dermatitis, and allergic rhinitis—to keratoconus risk, highlighting a dose-dependent association and the role of healthcare utilization in case asc

Sep 9, 2026
Diabetes & Endocrinology

Sex-Specific Associations Between Adiposity and Dry Eye Disease: Insights from a Large UK Biobank Study

Central obesity in women and high overall body fat in men are linked to increased odds of dry eye disease, with distinct metabolic pathways implicated, based on a retrospective analysis of over 480,000 UK Biobank participants.

Sep 9, 2026
Clinical Updates

Event-Based Progression Detection in Glaucoma: Integrating OCT, OCT Angiography, and Visual Field Metrics

This review synthesizes recent evidence on event-based progression detection in glaucoma, highlighting that OCTA vessel density may identify progression earlier than structural OCT or visual field testing, with important implications for cl

Sep 9, 2026
Clinical Updates

Longitudinal Trajectories of 3-Dimensional Eye Shape and Pathological Sequelae in High Myopia: Implications for Personalized Surveillance

This review synthesizes longitudinal evidence on 3D eye shape remodeling in high myopia, linking distinct morphologic trajectories to sight-threatening outcomes and supporting individualized risk stratification beyond axial length alone.

Sep 9, 2026
Clinical Updates

Safety and Effects of Gildeuretinol Acetate on Retinal Atrophic Lesions in Stargardt Disease: Insights from the TEASE-1 Randomized Clinical Trial

This review synthesizes evidence from the TEASE-1 trial and related studies on gildeuretinol acetate, highlighting its safety profile and modest efficacy in slowing retinal atrophic lesion growth in Stargardt disease over 24 months.

Sep 7, 2026Sign in to read
news

Prevalence and Characteristics of Null Studies in Ophthalmology: A Comprehensive Analysis from 2014 to 2025

A large-scale PubMed analysis reveals that one in five ophthalmology studies report null primary outcomes, with declining prevalence over time and notable differences in funding, design, and journal impact between null and positive studies.

Sep 5, 2026
Diabetes & Endocrinology

Impact of Neighborhood Socioeconomic Deprivation on Diabetic Retinopathy Screening Adherence in Medicare Beneficiaries

Increasing neighborhood socioeconomic deprivation is associated with reduced adherence to annual diabetic retinopathy screening among Medicare patients, highlighting disparities in preventive eye care.

Aug 31, 2026Sign in to read
news

Long-Term Incidence and Risk Factors for Glaucoma: Insights from the Gangnam Eye Cohort Study

A 10-year Korean cohort study reveals that retinal arteriosclerosis, intraocular pressure, age, serum uric acid, and cholesterol levels significantly increase the risk of structural glaucoma conversion.

Aug 31, 2026Sign in to read
Clinical Updates

Digital Defocus Vision Training Using Virtual Reality for Myopia Control: Current Evidence and Clinical Implications

Virtual reality-based digital defocus vision training (DDVT) shows promise as a home-based adjunct to slow myopia progression in children, with randomized trial data demonstrating modest reductions in axial length and refractive error progr

Aug 31, 2026
news

Evaluating HOTV Versus Tumbling E Vision Tests for Effective Pediatric Screening

This study compares HOTV and tumbling E vision tests in children aged 3 to 15, demonstrating HOTV’s superior accuracy and suitability for children under 8, potentially reducing unnecessary referrals in pediatric vision screening.

Aug 31, 2026
news

Beyond Vision Loss: Psychosocial Factors Influencing Psychological Distress in Primary Open-Angle Glaucoma

This study reveals psychosocial factors such as social support and self-efficacy significantly influence psychological distress in primary open-angle glaucoma, beyond clinical disease measures.

Aug 31, 2026
news

IOP Stress Testing Identifies Glaucoma Eyes at Risk of Fast Progression Despite Controlled Office Pressure

A stress test measuring intraocular pressure identifies glaucoma patients at risk of rapid progression despite normal office pressure readings, offering complementary prognostic insights beyond routine checks.

Aug 27, 2026
news

Intraday Upper Blepharoplasty Closure: Comparing Intradermal and Continuous Sutures for Optimal Outcomes

This paired-eye randomized study evaluates the aesthetic results of intradermal versus continuous external sutures in upper blepharoplasty, revealing similar long-term scar quality and high patient satisfaction.

Aug 26, 2026
news

Long-Term Efficacy and Visual Field Outcomes of Selective Laser Trabeculoplasty in Glaucoma Management

This study evaluates long-term outcomes of selective laser trabeculoplasty (SLT) in controlling intraocular pressure and preventing visual field deterioration, identifying clinical factors influencing effectiveness and progression risk.

Aug 26, 2026
Allergy & Immunology

Immune-Mediated Disorders and Central Serous Chorioretinopathy: Clinical Insights from the MICRoN Report 21

This study reveals that central serous chorioretinopathy (CSCR) in patients with immune-mediated disorders exhibits distinct clinical and imaging features, with immune-mediated status linked to poorer visual outcomes and higher recurrence,

Aug 26, 2026
Diabetes & Endocrinology

Teprotumumab Versus Intravenous Glucocorticoids in Thyroid Eye Disease: Insights from a Japanese MRI Study

This study evaluates teprotumumab’s effectiveness for thyroid eye disease in Japanese patients, revealing notable improvements in orbital inflammation and proptosis compared to intravenous glucocorticoid therapy with distinct MRI-base

Aug 26, 2026Sign in to read
Superintelligence

AI Writing Vocabulary in Ophthalmology: Faster Non-Native Adoption, Unchanged Outcomes

This study examines the increased use of AI-associated writing vocabulary in ophthalmology articles, revealing faster adoption by non-native English authors without changes in publication frequency or journal quality.

Aug 24, 2026Sign in to read
Infectious Diseases

Temporal Dynamics of Posterior Segment Imaging in Ocular Syphilis: Clinical Correlates and Laboratory Insights

This study elucidates distinct temporal patterns of posterior segment imaging features in ocular syphilis correlated with symptom duration and laboratory markers, enhancing diagnostic timing and clinical interpretation.

Aug 24, 2026
Clinical Updates

Malignancy Risk after Ophthalmic Herpes Infection within a Diverse United States Cohort: Clinical Insights and Implications

Ophthalmic herpes infections generally do not increase overall malignancy risk, but herpes zoster ophthalmicus (HZO) elevates cancer risk in patients with immune dysregulation, underscoring the need for tailored oncologic vigilance.

Aug 24, 2026
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