Long-Term Incidence and Risk Factors for Glaucoma: Insights from the Gangnam Eye Cohort Study

Highlight

• Over a mean 13-year follow-up, structural glaucoma conversion occurred in 2.3% of a large Korean health screening cohort.
• Older age, higher intraocular pressure, retinal arteriosclerosis, elevated serum uric acid, and increased total cholesterol independently predicted glaucoma risk.
• Retinal arteriosclerosis visible on routine fundus imaging emerges as a significant microvascular risk marker, suggesting a vascular component in glaucoma pathogenesis.
• Systemic metabolic factors, alongside ocular parameters, may enhance glaucoma risk stratification in preventive screening settings.

Study Background