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MedXY News/Ophthalmology

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Ophthalmology

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Unraveling Mid-phase Hyperfluorescent Plaques in Central Serous Chorioretinopathy: Insights from Multimodal Imaging

This study elucidates the dynamic nature and structural correlates of mid-phase hyperfluorescent plaques on ICGA in CSCR, highlighting their progression stages and OCT features that signal disease activity.

Oct 8, 2026
news

Impact of Ocular Proton Therapy on Corneal Subbasal Nerve Plexus in Uveal Melanoma: Longitudinal Confocal Microscopy Findings

Ocular proton therapy causes significant decreases in corneal nerve fiber parameters in uveal melanoma patients, with partial recovery by 12 months and minimal changes in corneal sensitivity and patient-reported outcomes.

Oct 8, 2026Sign in to read
Clinical Updates

Early Optic Nerve Head Swelling Rate Predicts Visual Outcome Deterioration in Nonarteritic Anterior Ischemic Optic Neuropathy: An Evidence-Based Review

Early rapid optic nerve head swelling in NAION correlates with worse visual outcomes, with OCT measures of pONHV and mGCIPL thinning providing prognostic insights within days of symptom onset.

Oct 7, 2026Sign in to read
Clinical Updates

Early Optic Nerve Head Swelling Rate Correlates with Visual Decline in Nonarteritic Anterior Ischemic Optic Neuropathy: An Evidence-Based Review

This review synthesizes longitudinal OCT findings and clinical outcomes in NAION, highlighting the prognostic value of early optic nerve head swelling rates for visual impairment progression, and discusses mechanistic and translational impl

Oct 6, 2026
Cardiology

Cholesteryl Ester Transfer Protein Inhibition: A Double-Edged Sword in Cardiovascular Health and Age-Related Macular Degeneration Risk

Genetic analyses reveal that cholesteryl ester transfer protein (CETP) inhibition, while beneficial for cardiovascular disease, is associated with an increased risk of age-related macular degeneration (AMD) across European and East Asian po

Oct 6, 2026
news

Remote Intraocular Pressure Monitoring and Novel Threshold Metrics Predict Visual Field Progression in Treated Open-Angle Glaucoma

Novel IOP metrics from remote home tonometry reflecting exceeding patient-specific IOP targets are significantly associated with visual field progression in treated open-angle glaucoma, outperforming conventional in-office measures.

Oct 6, 2026
Infectious Diseases

Distinct Clinical Profiles and Outcomes of Culture-Positive Endogenous Endophthalmitis by Pathogen: Insights from a 12-Year Multicenter Study

This multicenter study of 305 eyes over 12 years reveals pathogen-specific clinical features and outcomes in culture-positive endogenous endophthalmitis, highlighting unique presentations, prognosis, and risks especially for gram-negative a

Oct 1, 2026Sign in to read
news

Decoding Structure-Function Links in Early Atrophic Age-Related Macular Degeneration: Implications for Targeted Assessment and Management

This study reveals distinct structure-function correlations in early atrophic AMD, showing lesion size correlates with localized sensitivity loss, while lesion proximity to the fovea predicts central vision and reading outcomes, supporting

Oct 1, 2026Sign in to read
news

Orbital and Periorbital Epithelioid Hemangioma: Clinical and Radiological Insights from a Multicentre Study of 25 Cases

This multicentre observational study characterizes the clinicoradiological profile and treatment outcomes of 25 orbital and periorbital epithelioid hemangioma cases, highlighting superior orbital tropism, a hypervascular MRI phenotype, and

Oct 1, 2026
Clinical Updates

Cluster-Based Structural Phenotypes of Chronic Central Serous Chorioretinopathy: Clinical and Imaging Insights

Unsupervised clustering defines three structural phenotypes in chronic CSC, linking photoreceptor damage with choroidal changes and visual prognosis, refining disease stratification beyond photoreceptor staging alone.

Sep 30, 2026
Clinical Updates

Ten-Year Update of a Global Survey of Corneal Transplant and Eye Banking: Addressing Supply-Demand Disparities and Evolving Practices

This review presents a comprehensive ten-year update on global corneal transplantation and eye banking, highlighting persistent supply-demand gaps, income-based disparities, surgical trends, and emerging innovations to improve equitable acc

Sep 30, 2026Sign in to read
news

Advancing Blepharoptosis Assessment: Smartphone-Based 3D Ocular Reconstruction Enhances Precision and Clinical Decision-Making

A multi-center study validates a smartphone-based 3D ocular reconstruction tool that automates quantitative blepharoptosis assessment, showing high accuracy and potential to standardize external ocular evaluations.

Sep 29, 2026
news

Effective Retinal Detachment Prevention in Type 2 Stickler Syndrome Using Cambridge Prophylactic Cryotherapy

Prophylactic cryotherapy significantly lowers retinal detachment risk in Type 2 Stickler syndrome, demonstrating safety and efficacy in a large national cohort study.

Sep 29, 2026Sign in to read
news

Hess Screen Test: A Crucial Tool to Differentiate Decompensated Esophoria from Sagging Eye Syndrome

This study demonstrates that the Hess Screen Test reveals greater esodeviation in decompensated esophoria compared to prism cover test measurements, effectively distinguishing it from sagging eye syndrome, with implications for diagnosis an

Sep 28, 2026
news

EYS-Associated Retinal Degeneration in South Korea: Insights into Genetic Variability, Clinical Features, and Disease Progression

This comprehensive South Korean study characterizes the genetic landscape, clinical phenotype, and natural history of EYS-associated retinal degeneration, establishing progression benchmarks for future gene therapy trials.

Sep 28, 2026
news

Optimizing Management of Conjunctival Melanocytic Lesions: A Sequential Multimodal Treatment Framework

A retrospective cohort study demonstrates that a tailored, stepwise multimodal approach effectively controls conjunctival melanocytic lesions with reduced recurrence and metastasis risks, guided by lesion grade and clinical features.

Sep 26, 2026Sign in to read
news

Retinal Vasculometry Predicts Visual Field Progression in Primary Open Angle Glaucoma: Insights from Automated Fundus Photography Analysis

Baseline retinal vascular features quantified by automated deep learning on fundus photographs are associated with future visual field decline in primary open-angle glaucoma, offering potential prognostic biomarkers to enhance patient risk

Sep 24, 2026
news

Predictors of Vision Loss in Chronic Stevens-Johnson Syndrome: Insights from a Nationwide Multicenter Cohort Study

This study identifies key clinical features and risk factors predicting surgery and vision loss in chronic Stevens-Johnson syndrome, emphasizing the need for early referral and standardized care protocols.

Sep 24, 2026
news

Rising Incidence and Clinical Complexity of Non-Infectious Pediatric Uveitis in the US: Insights from a Decade of TriNetX Data

This study analyzes the rising incidence and prevalence of non-infectious pediatric uveitis in the United States, detailing demographic distributions, ocular complications, systemic associations, and treatment patterns from 2016 to 2025 usi

Sep 23, 2026
Clinical Updates

Centralized Multidisciplinary Retinoblastoma Care: Closing Outcome Gaps in Resource-Limited Settings with Telemedicine and Advanced Globe Salvage

Centralized multidisciplinary retinoblastoma care incorporating telemedicine and international partnership at KHCC improved survival and globe salvage rates to levels comparable with high-income countries, demonstrating a scalable model for

Sep 23, 2026
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