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Comprehensive pre- and early postoperative models predict acute kidney injury and need for renal replacement after lung transplantation, improving risk stratification and enabling targeted nephroprotection.
Researchers unveil ciliogenic pancreatopathy, a new pancreatic disease connected to ciliary gene mutations, highlighting its clinical significance in patients with syndromic ciliopathies and kidney dysfunction.
Finerenone reduces mortality, cardiovascular, and kidney complications in cardio-kidney-metabolic syndrome patients regardless of cancer history, while patients with cancer experience greater disease burden and adverse events.
Pre-liver transplantation elevated serum renin levels correlate with increased intraoperative vasopressor use and postoperative acute kidney injury, suggesting its potential as a predictive biomarker for perioperative management and renal r
Spatially distinct macrophage subsets interact with heterogeneous myofibroblast populations in lupus nephritis, driving maladaptive fibrosis and chronic kidney injury. Identifying these fibroinflammatory circuits offers promising targets fo
This review synthesizes evidence showing that Medicaid expansion under the Affordable Care Act significantly reduced 1-year mortality among young adults starting dialysis by improving insurance coverage and access to nephrology care.
Sequential use of normothermic regional perfusion and hypothermic machine perfusion in kidney transplants from DCD donors reduces delayed graft function, highlighting enhanced organ preservation strategies.
A multicenter cohort study shows that in critically ill patients undergoing continuous renal replacement therapy, mortality is more closely associated with fluid balance changes than net ultrafiltration rate, emphasizing patient-specific fl
This article reviews evidence linking cardiovascular-kidney-metabolic syndrome stages to liver fibrosis severity, progression, and liver-related events in metabolic dysfunction-associated steatotic liver disease (MASLD). Higher CKM stages i
This study identifies pre-transplant left atrial volume index as a potential predictor for overall one-year morbidity following kidney transplantation, highlighting its clinical relevance beyond traditional cardiac risk markers.
This study highlights varied outcomes of renal replacement therapy in critically ill patients, identifying subgroups who may benefit despite an overall increase in mortality risk.
RAAS inhibitors, used for kidney protection in sickle cell disease, may significantly exacerbate anemia by impairing erythropoiesis, warranting close hemoglobin monitoring in this vulnerable population.
Elevated plasma levels of H3.1 nucleosomes at ICU admission correlate with increased mortality and acute kidney injury requiring renal replacement therapy in sepsis, highlighting their potential as prognostic biomarkers.
This study explores whether renal resistive index (RRI) changes during a transient elevation of mean arterial pressure (MAP) can guide individualized MAP targets to optimize renal function in early septic shock, finding that RRI decrease do
A nationwide cohort study reveals that two-thirds of patients with primary hyperparathyroidism exhibit end-organ damage at diagnosis or during follow-up, yet few receive parathyroidectomy, underscoring missed opportunities to reduce morbidi
Intensive blood pressure lowering post-thrombectomy increases acute kidney injury risk, which correlates with poorer neurological outcomes in stroke patients. Careful BP management is crucial to prevent renal complications and optimize reco
An expert consensus (STARDaki) extends STARD to improve reporting of diagnostic test accuracy studies for acute kidney injury (AKI), specifying patient selection, reference standards, timing, assay details and test-retest reliability.
A machine-learning model using perioperative hemodynamic indices accurately predicted stage 2-3 acute kidney injury after orthotopic heart transplantation in 114 patients, with light gradient boosting machine achieving AUC 0.898.
A predefined subanalysis of EAST-AFNET 4 shows early rhythm control safely reduces cardiovascular events in recently diagnosed AF patients with CKD, with a trend toward greater benefit in this high-risk group.
A historical analysis reveals that policy decisions, financial incentives, and for-profit dialysis centers have contributed to persistent underuse of home dialysis in the US, especially among marginalized populations.
