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A multicenter study reveals that preserving donor hearts at 10°C results in better early graft function and one-year survival than traditional 4-8°C storage, suggesting a new standard for heart transplant preservation.
The 2026 ESC clinical consensus outlines creation of multidisciplinary Women’s Heart Centres to close gaps in diagnosis, management, and research for women’s cardiovascular disease across the life course.
This substudy of the CHIP-BCIS3 trial assessed the effects of elective left ventricular unloading via microaxial flow pump during complex PCI, finding reduced inotrope use but no significant hemodynamic or myocardial stunning benefits.
This study evaluates the incidence, severity, and predictors of extracranial bleeding in atrial fibrillation patients on oral anticoagulants, highlighting its substantial burden beyond major bleeds and informing bleeding risk management.
In patients with OSA and elevated blood pressure, comorbid insomnia is linked to a significantly greater blood pressure reduction following short-term CPAP therapy, highlighting the clinical importance of addressing both sleep disorders.
This study reveals that higher parity is associated with subtle reductions in myocardial strain during pregnancy, suggesting cumulative cardiovascular effects despite normal ejection fraction.
The VasCog-2-WSO criteria effectively detect MRI-defined vascular cognitive impairment in asymptomatic adults, correlating with increased cardiovascular risk and mortality, highlighting their utility for early diagnosis and community risk s
This 25-year prospective study evaluates the prognostic value of quantified mitral regurgitation (MR) severity and shows that early surgical intervention in upper-moderate MR improves long-term survival in asymptomatic patients.
In adults with repaired Tetralogy of Fallot undergoing pulmonary valve replacement, an electrophysiology-guided ablation strategy significantly reduces ventricular tachycardia inducibility and long-term arrhythmic risk compared to empiric a
Nongated coronary artery calcium (CAC) scoring from routine chest CT scans can predict cardiovascular events as reliably as standard gated CAC scans, offering widespread opportunities for risk stratification and preventive care.
This study demonstrates that dapagliflozin does not impair LDL catabolism but favorably shifts VLDL1 and VLDL2 catabolism toward normal physiology in type 2 diabetes, potentially contributing to reduced atherosclerosis risk.
Common bedside tests for peripheral arterial disease in diabetic patients show poor sensitivity, challenging their clinical reliability compared to advanced imaging modalities.
Acoramidis demonstrates substantial benefits in heart failure-related health status among ATTR-CM patients, significantly improving patient-reported outcomes and supporting its role in modifying disease trajectory.
JCAD, a junctional protein, independently predicts major adverse cardiovascular events (MACE) in acute coronary syndrome (ACS) patients with residual lipid and inflammatory risks, suggesting a key role in coagulation and fibrinolysis and a
This article reviews the accelerated evidence generation for anticoagulation in noncritically ill COVID-19 patients, highlighting how coordinated trials and data sharing influenced clinical guidelines and patient outcomes during the pandemi
A machine learning model using electronic health records effectively identifies patients at high risk of atrial fibrillation, enabling targeted screening and early diagnosis to prevent stroke.
In a randomized trial among Navajo patients with heart failure, an 8-week culturally tailored meal program reduced all-cause hospitalization or ED visits by 28% compared with usual dietary advice, with improvements in quality of life and food security.
In the EARLY TAVR registry, treadmill stress testing was safe and unmasked symptoms in 15% of asymptomatic severe aortic stenosis patients. Yet 20% of those with an indication for prompt aortic valve replacement remained untreated after one year.
A predefined subanalysis of EAST-AFNET 4 shows early rhythm control safely reduces cardiovascular events in recently diagnosed AF patients with CKD, with a trend toward greater benefit in this high-risk group.
A meta-analysis of 23 observational studies shows higher MIND diet adherence is associated with a 55% lower cancer risk and reduced all-cause and CVD mortality. Separately, the MIND trial now provides genetic data to explore precision nutrition for cognitive decline.
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