Section
Chronic exposure to fine particulate matter (PM2.5) is linked to epicardial coronary endothelial dysfunction, an early marker of coronary artery disease, as demonstrated by invasive coronary vasoreactivity testing.
The FAVOR III China trial demonstrates that QFR-guided percutaneous coronary intervention significantly reduces major adverse cardiac events over 5 years, mainly by decreasing myocardial infarction and ischemia-driven revascularization comp
Integration of late gadolinium enhancement corridors and high-risk genotypes markedly improves ventricular arrhythmic risk prediction beyond traditional ejection fraction metrics in nonischemic dilated cardiomyopathy.
Macrotroponin complexes commonly cause discordant cardiac troponin elevations in the general population, notably troponin I, without conferring increased cardiovascular risk, underscoring the need to recognize assay interference for accurat
A newly developed clinical likelihood score accurately distinguishes pulmonary arterial hypertension patients with venous or capillary involvement (PVOD/PCH), enabling earlier diagnosis, tailored therapy, and timely transplant referral.
This Finnish nationwide study demonstrates that patients with atrial flutter have a substantially lower risk of ischaemic stroke compared to those with atrial fibrillation, highlighting important differences in thromboembolic risk profiles
A multinational study reveals that combined exposure to heat waves and substantial landscape fire-sourced air pollution significantly increases cardiovascular mortality, particularly from heart failure, more than either hazard alone, unders
Aficamten, a cardiac myosin inhibitor, demonstrated significant improvements in symptoms, diastolic function, and biomarkers in nonobstructive hypertrophic cardiomyopathy across multiple trials, including the pivotal ACACIA-HCM study.
Decompensated cirrhosis markedly elevates mortality, complications, and costs following cardiac surgery. Optimized risk models and tailored management are essential for improved patient outcomes.
This study evaluates cardiovascular and bone health outcomes after bilateral oophorectomy during benign hysterectomy in postmenopausal women, highlighting increased risk for cardiovascular predisposition but no rise in clinical cardiovascul
Germline and somatic variants in DNMT3A and other CHIP genes elevate pulmonary arterial hypertension risk, including connective tissue disease-associated forms, through pro-inflammatory pathways, highlighting novel biomarkers and therapeuti
The FUSION randomized trial demonstrates that adding CT-derived FFR to coronary CTA significantly reduces unnecessary invasive angiographies without affecting clinical outcomes, cost, or quality of life in stable CAD patients with intermedi
This article reviews the ViVA trial assessing vericiguat, an sGC stimulator, in angina patients with coronary vasospasm but no obstructive coronary artery disease. The study found no significant improvement in vasodilator function or angina
A nationwide observational study reveals tocilizumab use in giant cell arteritis significantly lowers major adverse cardiovascular events compared to methotrexate, highlighting its potential cardiovascular benefits beyond inflammation contr
The VESALIUS-CV trial demonstrates that evolocumab lowers all-cause and cardiovascular mortality in patients with high cardiovascular risk but no prior myocardial infarction or stroke, highlighting its survival benefits in primary preventio
The BRIDGE trial demonstrates that protocol-driven early intensive lipid-lowering therapy significantly improves guideline-recommended LDL-C target attainment in acute coronary syndrome patients, fostering better cardiovascular risk control
TAPIS subgroup analysis reveals that ticagrelor-aspirin combined with thrombolysis may improve outcomes in moderate ischemic stroke patients with multiple acute infarcts, without increasing hemorrhage risk, suggesting infarct pattern as a p
This study reveals that central autonomic network alterations in temporal lobe epilepsy patients contribute to interictal cardiorespiratory dysfunction, potentially increasing SUDEP risk, and highlights connectivity changes post-surgery imp
This study reveals distinct left atrial structural and functional changes associated with obesity in atrial fibrillation patients, highlighting a load-related atrial remodeling that may underlie increased risks of atrial fibrillation and he
Combining left ventricular global longitudinal strain and right atrial reservoir strain greatly improves risk prediction and stratification in pulmonary arterial hypertension, outperforming conventional imaging and clinical models.
