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The PIONIR randomized crossover trial demonstrates that a specific Tasty&Healthy diet significantly reduces fecal calprotectin levels, a marker of gut inflammation, in first-degree relatives at high risk for Crohn’s disease, sugge
A randomized clinical trial demonstrates that a self-guided internet intervention significantly reduces seizure frequency and improves anxiety in adults with functional seizures, offering a scalable treatment alternative to standard care.
This study evaluates semaglutide’s benefits over dulaglutide or liraglutide among diabetic hemodialysis patients, highlighting improved survival, reduced hospitalizations, and greater weight loss with semaglutide.
The DANCODE trial demonstrates that combined vitamin K2 and D3 supplementation reduces the progression of severe coronary artery calcification over 24 months without increasing noncalcified plaque burden, offering a promising adjunctive str
This study assesses the global track measurement against traditional imaging metrics to better predict engagement risk in anterior shoulder instability due to bipolar bone loss, highlighting its potential and need for further validation.
This study compares the effectiveness of inpatient rehabilitation facilities and skilled nursing facilities on functional recovery after acute stroke, showing inpatient care offers greater long-term home time.
Surgical trauma from oral cancer reconstruction disrupts oral microbiota; staged oral irrigation, especially using bipolar water, supports microbial stabilization, lowers fungal presence, and improves patient comfort, aiding postoperative r
This review synthesizes phase 3 clinical evidence comparing divarasib, sotorasib, and adagrasib for KRAS G12C-mutated NSCLC, highlighting divarasib’s superior efficacy and safety, dose optimization insights, real-world data, and trans
This trial shows that a six-month eHealth-guided exercise program significantly improves peak oxygen uptake and mental health quality of life in adults recovering from COVID-19, outperforming standard physical activity advice.
A multicentre retrospective study shows early controlled mobilisation in nonoperatively treated Mason type I and II radial head fractures leads to modest improvements in function, pain, and return to work times, with no significant increase
A novel polyurethane resin cement incorporating 3% DMAHDM exhibits potent antibacterial effects, maintains strong mechanical properties, and offers promising dual-action caries prevention for indirect restorations.
Two phase 3 trials establish remibrutinib, a BTK inhibitor, as more effective and better tolerated than teriflunomide in relapsing multiple sclerosis, supporting its potential as a new oral treatment.
A concise guide to the new AAP-endorsed curriculum framework that standardizes advocacy training in pediatric residency and fellowships using a socioecological model and practical, competency-linked tools for graduate medical education.
A 10-year follow-up of early rheumatoid arthritis patients treated with a treat-to-target strategy shows sustained remission leads to lasting clinical, structural, and functional benefits, supporting current treatment guidelines.
Recent large-cohort analyses reveal that donor hospital distance from OPO headquarters does not increase deceased donor kidney nonuse, while policy changes like KAS250 temporarily raise nonuse rates but overall kidney utilization continues
This large cohort study demonstrates that biologic therapy in pregnant women with psoriasis is not associated with increased adverse pregnancy outcomes and may reduce risks of spontaneous abortion and gestational diabetes.
A composite internal stabilization strategy using an internal hemostatic network significantly reduced postoperative hematoma incidence to zero in 356 facelift procedures, compared to 5.9% with conventional methods, enabling safer recovery
An analysis of 27,773 pediatric tracheal intubations reveals 1.2% associated cardiac arrest, highlighting preventable factors such as multiple intubation attempts and benefits linked to video laryngoscopy and specific medications.
Despite substantial potential revenue, only 15% of US primary care clinicians adopted Medicare’s Advanced Primary Care Management codes in 2025, with administrative challenges as key barriers.
A long-term follow-up of the SPRINT trial shows no significant difference in recurrent stroke or mortality rates between initial low and moderate fixed doses of hydroxyurea in sickle cell disease, emphasizing event clustering within the fir
