Our website uses essential cookies and, with your consent, additional cookies to measure performance and improve our services. Cookie Policy.
You can change your choice at any time.
Tag
This article synthesizes evidence from a large-scale individual participant data meta-analysis, demonstrating that early perihematomal edema growth (at 24 and 72 hours) is an independent predictor of death and disability after intracerebral
Recent data from the ARIC study and emerging expert consensus are redefining primary aldosteronism. Rather than a rare, all-or-nothing condition, it is now viewed as a broad spectrum where even subclinical elevations significantly increase
This article examines a Phase 2a trial investigating eslicarbazepine acetate for preventing post-stroke epilepsy. While the primary endpoint was not met due to recruitment challenges, the study provides a critical framework for future antie
A major AHA scientific statement forecasts a significant increase in cardiovascular disease and risk factors among U.S. women by 2050. It highlights rising rates of obesity and hypertension while emphasizing the urgent need for targeted int
The EMPHASIS trial reveals that oral minocycline initiated within 72 hours of an acute ischaemic stroke significantly enhances functional independence at 90 days. This multicentre study provides robust evidence for a well-tolerated, accessi
This population-based cohort study highlights how cumulative psychosocial stress across the life course significantly escalates the risk of neurovascular and neurodegenerative diseases, identifying depression as a critical target for interv
A post-hoc analysis of 1,040 LVO stroke patients reveals that the prognostic value of specific brain regions varies significantly between early (0-6h) and extended (6-24h) time windows, identifying the insula, caudate, and M6 as early-windo
The TenCRAOS trial demonstrated that intravenous tenecteplase administered within 4.5 hours of acute central retinal artery occlusion does not improve vision recovery compared to aspirin and carries significant safety risks, including fatal
A secondary analysis of the PRESTIGE-AF trial reveals that specific MRI markers, including cortical superficial siderosis and macrohemorrhages, are more potent predictors of recurrent intracerebral hemorrhage than hematoma location alone, o
The ANGEL-REBOOT trial reveals that while bailout angioplasty (BAOS) increases short-term procedural risks, it significantly improves one-year functional outcomes and reduces stroke recurrence in patients with failed thrombectomy or high-gr
The landmark BHF PROTECT-TAVI trial reveals that cerebral embolic protection (CEP) does not reduce periprocedural stroke or cognitive impairment following TAVI. This large-scale study challenges the routine use of embolic filters, suggestin
A long-term analysis of the FOURIER trials reveals that achieving ultra-low LDL-C levels (<40 mg/dL) significantly reduces recurrent stroke and major cardiovascular events in stroke survivors, without increasing hemorrhagic stroke risk,
A post hoc analysis of the SWITCH trial demonstrates that the clinical benefits of decompressive craniectomy in reducing death and severe disability are consistent across different anatomical locations of deep supratentorial intracerebral h
A multicenter cohort study (ERNA-IAO) demonstrates that endovascular recanalization significantly increases the risk of stroke and death compared to medical treatment alone in patients with symptomatic nonacute intracranial artery occlusion
The SECURIS study demonstrates that emergent carotid artery stenting (eCAS) for tandem lesions in acute ischemic stroke significantly improves one-year functional outcomes and recanalization success without increasing hemorrhagic risks comp
The multicenter CERES-TANDEM study provides Class II evidence that emergent carotid stenting (eCAS) during thrombectomy for tandem lesions significantly improves 90-day functional recovery without increasing the risk of symptomatic intracra
Long-term data from the ATTENTION trial reveal that endovascular thrombectomy significantly improves functional outcomes and survival at three years for patients with basilar artery occlusion, establishing it as a durable standard of care.
A pooled analysis of over 11,000 patients from the INTERACT trials demonstrates that intensive blood pressure reduction significantly improves functional recovery in acute intracerebral hemorrhage, with the most robust benefits observed whe
The MSU-TELEMED trial demonstrates that a telemedicine model for mobile stroke units significantly improves neurologist resource utilization while maintaining safety, outperforming the traditional onboard neurologist model in a hierarchical
The MSU-TELEMED trial demonstrates that telemedicine models for Mobile Stroke Units are superior to onboard neurologist care. By dramatically improving physician resource utilization without compromising safety, telemedicine provides a more