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Mortality and Morbidity After Below-Knee Amputation in Diabetes: Insights from a 25-Year English Cohort Study
Diabetes & Endocrinologydiabetesbelow-knee amputation

Mortality and Morbidity After Below-Knee Amputation in Diabetes: Insights from a 25-Year English Cohort Study

By MedXY|Sep 17, 2026

This large-scale England study reveals persistently high mortality after below-knee amputation in diabetes, with one-year mortality exceeding 23%, emphasizing the need for targeted interventions focused on older, female, and comorbid patien

Global Trends in the Burden of Ischemic Stroke Attributable to Diabetes Versus Atrial Fibrillation
Cardiologyepidemiologydiabetes

Global Trends in the Burden of Ischemic Stroke Attributable to Diabetes Versus Atrial Fibrillation

By MedXY|Sep 12, 2026

This study analyzes global trends comparing ischemic stroke burdens linked to diabetes and atrial fibrillation, revealing a rising impact of diabetes-related stroke and highlighting the need for targeted interventions.

Charcot Neuro-Osteoarthropathy in Diabetes: High Risk of Hospitalization, Amputation, and Mortality Revealed by Regional Cohort Study
Diabetes & Endocrinologysurvivaldiabetes

Charcot Neuro-Osteoarthropathy in Diabetes: High Risk of Hospitalization, Amputation, and Mortality Revealed by Regional Cohort Study

By MedXY|Sep 5, 2026

Charcot neuro-osteoarthropathy (CNO) in people with diabetes is linked to frequent emergency hospitalizations, substantial risk of limb amputation, and reduced survival, highlighting urgent need for intensified multidisciplinary care.

Bridging the Gap: Ensuring Outpatient Follow-Up After Emergency Department Visits for Diabetes
Diabetes & Endocrinologyemergency departmentdiabetes

Bridging the Gap: Ensuring Outpatient Follow-Up After Emergency Department Visits for Diabetes

By MedXY|Sep 1, 2026

Less than half of diabetes patients discharged from the emergency department receive timely outpatient follow-up, underscoring critical care continuity gaps that require targeted interventions to improve outcomes.

Refining Diabetes Classification in East Asians: Harnessing Data-Driven Clusters for Precision Medicine
Diabetes & EndocrinologyData-driven clusteringEast Asian phenotype

Refining Diabetes Classification in East Asians: Harnessing Data-Driven Clusters for Precision Medicine

By MedXY|Aug 24, 2026

This article reviews data-driven diabetes subtypes in East Asians, highlighting unique pathological features, genetic influences, and complication risks, emphasizing personalized treatment strategies for optimized care.

Unmasking Silent Heart Failure in Diabetes: Insights from the TARTAN-HF Trial
CardiologydiabetesHFpEF

Unmasking Silent Heart Failure in Diabetes: Insights from the TARTAN-HF Trial

By MedXY|Aug 21, 2026

The TARTAN-HF trial demonstrated that targeted natriuretic peptide screening in high-risk diabetic patients uncovers a high prevalence of undiagnosed heart failure, mainly HFpEF, enabling earlier treatment initiation and improved clinical c

Age-Specific Excess Healthcare Burden of Diabetes: Beyond Traditional Complications
Diabetes & EndocrinologycomplicationsHospital Admissions

Age-Specific Excess Healthcare Burden of Diabetes: Beyond Traditional Complications

By MedXY|Aug 21, 2026

Diabetes significantly increases inpatient admissions and ED visits across all ages, driven increasingly by nontraditional complications. Age-specific risks reveal shifting patterns in healthcare utilization that call for tailored clinical

Glucose in Motion: Insights into Temporal Patterns of Glycemic Control in Real-World Diabetes Management
Clinical Updatesreal‑world evidenceGlycemic Control

Glucose in Motion: Insights into Temporal Patterns of Glycemic Control in Real-World Diabetes Management

By MedXY|Aug 18, 2026

This review synthesizes evidence on daily and weekly patterns of glycemic control in real-world CGM data, highlighting small but consistent temporal variations that inform personalized diabetes care.

Unveiling Heart Failure Risks in Newly Diagnosed Diabetes: The Critical Role of Insulin Resistance and Renal Function
Cardiologyepidemiologydiabetes

Unveiling Heart Failure Risks in Newly Diagnosed Diabetes: The Critical Role of Insulin Resistance and Renal Function

By MedXY|Aug 13, 2026

This study reveals a high heart failure risk within 5 years of diabetes diagnosis, highlighting insulin resistance and reduced kidney function as independent predictors beyond conventional risk factors.

Optimizing Diabetes Management in Cirrhosis: A Practical Clinical Guide
Diabetes & Endocrinologycirrhosisdiabetes

Optimizing Diabetes Management in Cirrhosis: A Practical Clinical Guide

By MedXY|Aug 18, 2026

Cirrhosis entwined with diabetes presents unique clinical challenges. This article offers a pragmatic framework for diagnosis, tailored therapies, and multidisciplinary care to enhance outcomes across liver disease stages.

GLP-1 Receptor Agonists May Reduce Hospital Admissions for Alcohol and Substance Use Disorders: Insights from a Swedish Nationwide Study
Diabetes & Endocrinologyhospitalisation ratesdiabetes

GLP-1 Receptor Agonists May Reduce Hospital Admissions for Alcohol and Substance Use Disorders: Insights from a Swedish Nationwide Study

By MedXY|Aug 10, 2026

This Swedish register-based study reveals that GLP-1 receptor agonists are associated with significantly reduced hospitalisations for alcohol and substance use disorders during treatment, with some lasting benefits after discontinuation of

Structured Telehealth Community Health Worker-Clinician Feedback and Diabetes Outcomes: A Randomized Clinical Trial
Diabetes & Endocrinologytelehealthdiabetes

Structured Telehealth Community Health Worker-Clinician Feedback and Diabetes Outcomes: A Randomized Clinical Trial

By MedXY|Aug 5, 2026

This study demonstrates that a telehealth-supported community health worker program with structured feedback loops significantly improves diabetes control and care adherence in low-income Hispanic adults.

Determinants of One-Year Success in Descemet Membrane Endothelial Keratoplasty: Insights from the Diabetes Endothelial Keratoplasty Study
Diabetes & Endocrinologycorneal transplantationdiabetes

Determinants of One-Year Success in Descemet Membrane Endothelial Keratoplasty: Insights from the Diabetes Endothelial Keratoplasty Study

By MedXY|Aug 2, 2026

This article examines factors influencing the one-year success rate of DMEK in treating corneal endothelial dysfunction, highlighting the impact of operative complications and donor-recipient variables based on findings from the Diabetes En

Reassessing Diagnostic Tools for Peripheral Arterial Disease in Diabetes: Insights from the DMPAD Study
CardiologydiabetesDiagnostic accuracy

Reassessing Diagnostic Tools for Peripheral Arterial Disease in Diabetes: Insights from the DMPAD Study

By MedXY|Aug 4, 2026

Common bedside tests for peripheral arterial disease in diabetic patients show poor sensitivity, challenging their clinical reliability compared to advanced imaging modalities.

Hypoglossal Nerve Stimulation and Cardiovascular Disease Risk in Obstructive Sleep Apnea: A Comprehensive Review
Clinical Updatescardiovascular diseasediabetes

Hypoglossal Nerve Stimulation and Cardiovascular Disease Risk in Obstructive Sleep Apnea: A Comprehensive Review

By MedXY|Jul 24, 2026

This review synthesizes current evidence on the impact of hypoglossal nerve stimulation (HGNS) on cardiovascular disease incidence in obstructive sleep apnea patients, highlighting potential long-term cardiovascular benefits and mechanistic

Harnessing Real-World Evidence to Optimize GLP-1-Based Therapies: Insights from a NIDDK Workshop
Diabetes & EndocrinologydiabetesGLP-1 receptor agonists

Harnessing Real-World Evidence to Optimize GLP-1-Based Therapies: Insights from a NIDDK Workshop

By MedXY|Jul 7, 2026

A NIDDK workshop highlighted the crucial role of real-world evidence in addressing gaps about GLP-1 receptor agonists’ safety, effectiveness, adherence, and economic impact to improve clinical and regulatory decision-making.

Continuous Glucose Monitoring and Survival Benefits in Diabetic Veterans on Dialysis: Insights from a Nationwide Cohort
Diabetes & Endocrinologycontinuous glucose monitoringdiabetes

Continuous Glucose Monitoring and Survival Benefits in Diabetic Veterans on Dialysis: Insights from a Nationwide Cohort

By MedXY|Jul 1, 2026

Among U.S. veterans with diabetes on dialysis, continuous glucose monitoring (CGM) use was associated with significantly lower mortality risk compared to non-CGM use, highlighting CGM’s potential to improve survival in this high-risk

Diabetes and Sudden Cardiac Death: Findings from a Danish Nationwide Study
CardiologyCardiologydiabetes

Diabetes and Sudden Cardiac Death: Findings from a Danish Nationwide Study

By MedXY|Jun 7, 2026

A nationwide Danish study found that type 1 and type 2 diabetes substantially increase sudden cardiac death risk, especially in younger adults, and contribute meaningfully to shortened life expectancy.

Diabetes, Male Sex, and Low HBsAg, HDV RNA, and ALT Predict Spontaneous HDV Suppression in Chronic Hepatitis D
GastroenterologyALTchronic hepatitis D

Diabetes, Male Sex, and Low HBsAg, HDV RNA, and ALT Predict Spontaneous HDV Suppression in Chronic Hepatitis D

By MedXY|May 20, 2026

In 1,610 untreated chronic hepatitis D patients, spontaneous HDV suppression was uncommon but increased over time. Diabetes, male sex, and lower baseline HBsAg, HDV RNA, and ALT predicted suppression and fewer liver-related events.

Teprotumumab for Thyroid Eye Disease Carries a Measurable Long-Term Dysglycemia Risk
Diabetes & Endocrinologydiabeteshyperglycemia

Teprotumumab for Thyroid Eye Disease Carries a Measurable Long-Term Dysglycemia Risk

By MedXY|May 3, 2026

A large multinational cohort study found that teprotumumab use in thyroid eye disease was associated with higher risks of prediabetes, diabetes, and antidiabetes medication initiation over 5 years.

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