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A long-term analysis of the FOURIER trials reveals that achieving ultra-low LDL-C levels (<40 mg/dL) significantly reduces recurrent stroke and major cardiovascular events in stroke survivors, without increasing hemorrhagic stroke risk,
A post hoc analysis of the SWITCH trial demonstrates that the clinical benefits of decompressive craniectomy in reducing death and severe disability are consistent across different anatomical locations of deep supratentorial intracerebral h
A multicenter cohort study (ERNA-IAO) demonstrates that endovascular recanalization significantly increases the risk of stroke and death compared to medical treatment alone in patients with symptomatic nonacute intracranial artery occlusion
The SECURIS study demonstrates that emergent carotid artery stenting (eCAS) for tandem lesions in acute ischemic stroke significantly improves one-year functional outcomes and recanalization success without increasing hemorrhagic risks comp
The multicenter CERES-TANDEM study provides Class II evidence that emergent carotid stenting (eCAS) during thrombectomy for tandem lesions significantly improves 90-day functional recovery without increasing the risk of symptomatic intracra
Long-term data from the ATTENTION trial reveal that endovascular thrombectomy significantly improves functional outcomes and survival at three years for patients with basilar artery occlusion, establishing it as a durable standard of care.
A pooled analysis of over 11,000 patients from the INTERACT trials demonstrates that intensive blood pressure reduction significantly improves functional recovery in acute intracerebral hemorrhage, with the most robust benefits observed whe
The MSU-TELEMED trial demonstrates that a telemedicine model for mobile stroke units significantly improves neurologist resource utilization while maintaining safety, outperforming the traditional onboard neurologist model in a hierarchical
The MSU-TELEMED trial demonstrates that telemedicine models for Mobile Stroke Units are superior to onboard neurologist care. By dramatically improving physician resource utilization without compromising safety, telemedicine provides a more
A large-scale prospective study across England’s NHS reveals that AI imaging software significantly boosts endovascular thrombectomy rates for acute stroke patients. Implementation was associated with a 100% relative increase in treat
An IPD meta-analysis of six randomized trials (2313 patients) found IV alteplase before EVT modestly increased intracranial hemorrhage—particularly parenchymal hematoma—yet ICH risk must be balanced against IVT-associated improvements in re
A 523‑patient multicenter cohort found intravenous thrombolysis alone was associated with better 3‑month functional outcomes and lower mortality than endovascular thrombectomy (± IVT) for acute basilar artery occlusion after adjustment for
A multicenter retrospective cohort (OPEN-WINDOW) found that IV thrombolysis given beyond 4.5 hours before interhospital transfer for EVT was associated with higher rates of recanalization during transfer and better 3‑month functional outcom
Post hoc analyses of LAAOS III show surgical left atrial appendage occlusion (LAAO) during cardiac surgery lowers the proportion of cardioembolic and cortical infarcts and is associated with less disability and lower early mortality after i
A quality improvement program significantly increased obstructive sleep apnea testing in stroke and TIA patients, advancing guideline-based care in cerebrovascular health.
A secondary analysis of the TEMPO-2 trial shows that intravenous tenecteplase does not improve 90-day outcomes in minor disabling stroke defined by NIHSS scores, highlighting the need to reconsider thrombolysis in this patient population.
The INTERSTROKE study reveals how age modifies the relationship between vascular risk factors and acute stroke, highlighting age-specific prevention priorities to reduce stroke burden globally.
A recent randomized clinical trial demonstrates that 0° head-of-bed positioning prior to thrombectomy in patients with large vessel occlusion stroke preserves neurological stability and reduces mortality compared to the conventional 30° ele
The ANGEL-ASPECT trial demonstrates that endovascular therapy (EVT) significantly improves 1-year functional outcomes compared to medical management in patients with large ischemic stroke, confirming durable disability reduction despite sim
Stroke, a sudden interruption of brain blood flow, can lead to severe disability or death but is largely preventable. Early recognition and timely intervention can save lives and reduce complications.
