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A comprehensive meta-analysis of six US cohorts identifies vascular risk factors including smoking, hypertension, diabetes, chronic kidney disease, stroke history, and APOE ε4 genotype as significant predictors of late-onset epilepsy in old
The ReCCLAIM II trial demonstrates that rapid systemic hypothermia during mechanical thrombectomy for large-vessel occlusion stroke is feasible without delaying reperfusion, showing trends toward reduced infarct volume but raising safety co
Acute Imbalance Syndrome represents over half of stroke-related vertigo cases, distinct from Acute Vestibular Syndrome by lesion location and clinical presentation, crucial for accurate stroke diagnosis in emergency care.
A 2024 multicenter study in Amhara, Ethiopia found nearly 80% of stroke survivors experienced fall-related injuries, with older age, rural residency, and walking/turning activities as key risk factors.
National data show that Comprehensive Stroke Center status and trial participation independently predict reported stroke rates after TAVR, highlighting potential ascertainment bias affecting hospital performance metrics.
A large Ontario cohort study found that transient ischemic attack (TIA) significantly increases long-term dementia risk, rivaling stroke’s impact, underscoring the need for cognitive-focused prevention strategies.
Stroke incidence among young adults aged 20-54 is increasing despite a modest decline in 30-day fatality, linked to growing prevalence of vascular risk factors and substance use. This population-based study underscores urgent preventive nee
The EMBOL-AF Global Registry provides comprehensive data on stroke and systemic embolism post-atrial fibrillation ablation, highlighting incidence, timing, risk factors, and procedural impacts alongside evolving ablation strategies and long
This longitudinal study shows that retinal microvascular changes measured by OCTA correspond with cerebral small vessel disease progression and cognitive decline in mild ischemic stroke patients, highlighting OCTA’s potential as a non
In patients with distal and medium vessel occlusion strokes, tenecteplase achieves higher early recanalization rates and reduces early infarct growth compared to alteplase, supporting its preferential use in this clinical setting.
The STRATEGY trial assessed whether combining tirofiban with aspirin improves outcomes in branch atheromatous disease (BAD)-related stroke but found no significant benefit over aspirin alone in preventing neurological deterioration or recur
This prospective registry reveals a significantly increased risk of stroke or transient ischemic attack within 30 days after pulsed field ablation compared to radiofrequency ablation for atrial fibrillation, highlighting important safety co
A machine learning model using simple clinical tests within 72 hours poststroke accurately predicts 6-month upper-limb motor outcomes, aiding rehabilitation planning.
Damage to serotonergic and dopaminergic neurotransmitter-linked networks predicts variability in acute and chronic poststroke language impairment, offering new insights beyond traditional lesion metrics.
Highlight This unprecedented large-scale multinational study developed a semisupervised contrastive machine learning framework that generates a global
This retrospective analysis reveals that standard antiplatelet therapy may reduce mortality compared to thrombolysis in acute spontaneous spinal cord infarction, highlighting the need for cautious therapeutic decisions pending stronger evid
A secondary analysis of the INTERACT3 trial shows that younger adults (≤50 years) with intracerebral hemorrhage have lower mortality and disability but differ in risk factors and may benefit more from bundled care.
The MAD-MT score integrates clinical and procedural factors to optimize mechanical thrombectomy decisions in distal and medium vessel occlusion strokes, guiding tailored treatment and improving functional outcomes.
This study reveals that female stroke patients are less frequently screened for large vessel occlusion (LVO) yet have a higher LVO prevalence and comparable thrombectomy use to males, with better long-term outcomes post-thrombectomy.
Cerebral small vessel disease (SVD) significantly contributes to functional decline independently of bleeding or ischemic events during antithrombotic therapy, underscoring the need for targeted management strategies to address SVD burden i
