Tag
This study compares retinopathy of prematurity severity in US and Indian infants using an AI-derived vascular severity score, revealing epidemiological and pathophysiological differences that could impact diagnosis and management globally.
A comprehensive meta-analysis of six US cohorts identifies vascular risk factors including smoking, hypertension, diabetes, chronic kidney disease, stroke history, and APOE ε4 genotype as significant predictors of late-onset epilepsy in old
Nationwide analyses show that epilepsy markedly increases the risk of young-onset dementia (YOD) before age 65, with persistent associations even years after epilepsy diagnosis, underscoring the need for YOD risk assessment in epilepsy care
This study identifies a link between exposure to wildfire-specific PM2.5 air pollution and increased risks of head and neck cancers over a 10-year period, with notable effects on oral cavity, oropharyngeal, and laryngeal cancers.
More than one-third of Hispanic/Latino adults with diabetes exhibit diabetic retinopathy (DR), with significant variability across backgrounds. Hypertension notably associates with DR and vision-threatening DR, highlighting the need for tar
A large single-center cohort study found no increased incidence of malignancy in patients with IgG4-related disease (IgG4-RD). Smoking and older age increased malignancy risk, while female sex and submandibular gland involvement were protec
This review synthesizes evidence on the derivation and validation of a claims-based algorithm for identifying cardiogenic shock (CS), demonstrating its high diagnostic performance and enabling robust large-scale epidemiologic and long-term
This comprehensive 10-year ICU study reveals a low prevalence of positive pleural fluid cultures, highlights the significant link to suspected pleural infection, and associates culture positivity with higher 90-day mortality, informing targ
This review analyzes global sex disparities in cancer incidence, highlighting modifiable lifestyle and health factors — notably smoking, alcohol, and obesity — as key contributors differing by population context, with implications for tailo
A large Danish cohort study reveals that partner similarity for psychiatric disorders significantly inflates both prevalence and heritability estimates, highlighting important public health and genetic counseling implications.
Between 2015 and 2025, non-cystic fibrosis bronchiectasis prevalence in the US primary care population increased by 133%, predominantly affecting older, white, female patients with Medicare coverage.
This statewide cohort study reveals significantly higher incidence and earlier onset of systemic physical multimorbidity among people with schizophrenia-spectrum or bipolar disorders compared to matched controls, highlighting urgent needs f
A large-scale EHR study reveals a 133% increase in non-cystic fibrosis bronchiectasis prevalence in U.S. adults from 2015 to 2025, with marked demographic disparities.
The Rome V global epidemiology survey confirms a high prevalence of disorders of gut-brain interaction (DGBI) worldwide, consistent with prior Rome IV findings, underscoring a significant and persistent global clinical burden.
The PORTHOS study reveals a 16.5% prevalence of heart failure among Portuguese adults aged 50+, with HFpEF constituting over 90% of cases, mostly undiagnosed, highlighting the need for enhanced screening strategies in aging populations.
Analysis of SEER data from 2000-2021 reveals incidence, survival trends, and demographic disparities in US patients with myeloproliferative neoplasms, highlighting improved outcomes particularly in primary myelofibrosis and areas for furthe
Emerging evidence links high pesticide exposure events (HPEEs) in farmers to increased self-reported olfactory dysfunction, though objective smell testing yields inconclusive associations, highlighting critical gaps and methodological consi
Vulvar cancer exhibits significant recurrence rates, predominantly local, with survival declining sharply after recurrence. Awareness of recurrence-associated symptoms enhances early detection. Surgery remains pivotal in management, with fr
This study analyzes global trends comparing ischemic stroke burdens linked to diabetes and atrial fibrillation, revealing a rising impact of diabetes-related stroke and highlighting the need for targeted interventions.
This study reveals that individuals with Congenital Adrenal Hyperplasia (CAH) experience early, frequent, and complex hospitalizations with higher risk of severe outcomes, especially in infancy, compared to non-CAH patients, emphasizing the
