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Machine Learning-enhanced Steroid Profiling for Rapid Diagnosis of Congenital Adrenal Steroidogenesis Disorders
Diabetes & EndocrinologySteroid ProfilingCongenital Adrenal Disorders

Machine Learning-enhanced Steroid Profiling for Rapid Diagnosis of Congenital Adrenal Steroidogenesis Disorders

By MedXY|Sep 19, 2026

This article reviews a validated machine learning decision-tree model using LC-MS/MS steroid profiles to accurately and rapidly diagnose congenital disorders of adrenal steroidogenesis (CDAS), enhancing clinical decision-making and patient

Teplizumab Preserves Beta Cell Function in Youth with Newly Diagnosed Type 1 Diabetes: Insights from the PROTECT Trial Per-Protocol Analysis
© 2026 MedXY
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Diabetes & EndocrinologyBeta Cell PreservationTeplizumab

Teplizumab Preserves Beta Cell Function in Youth with Newly Diagnosed Type 1 Diabetes: Insights from the PROTECT Trial Per-Protocol Analysis

By MedXY|Sep 13, 2026

The PROTECT trial’s per-protocol analysis confirms teplizumab’s efficacy in preserving beta cell function, reducing insulin needs, and improving glycemic control in children and adolescents newly diagnosed with stage 3 type 1 di

Autoantibody Screening in Sibling-Dominant Pediatric Relatives of Type 1 Diabetes Patients: Prevalence, Determinants, and Psychological Impact
Diabetes & Endocrinologytype 1 diabetesanxiety

Autoantibody Screening in Sibling-Dominant Pediatric Relatives of Type 1 Diabetes Patients: Prevalence, Determinants, and Psychological Impact

By MedXY|Sep 6, 2026

This multicentre Turkish study identifies ZnT8 autoantibodies as predominant in young siblings at risk for type 1 diabetes and highlights gestational age as a protective factor, while revealing significant anxiety changes in children and pa

Impact of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Glucose Metabolism in Youths with Cystic Fibrosis: Insights from Continuous Glucose Monitoring
Diabetes & Endocrinologycystic fibrosiscontinuous glucose monitoring

Impact of Elexacaftor/Tezacaftor/Ivacaftor Therapy on Glucose Metabolism in Youths with Cystic Fibrosis: Insights from Continuous Glucose Monitoring

By MedXY|Sep 5, 2026

This study demonstrates that initiation of elexacaftor/tezacaftor/ivacaftor (ETI) therapy in children and adolescents with cystic fibrosis improves continuous glucose monitoring (CGM) metrics, correlating with better clinical outcomes.

Navigating Ethical Challenges in Pediatric Endocrinology: Case-Based Approaches and Principles
Diabetes & Endocrinologygrowth hormone therapymedical ethics

Navigating Ethical Challenges in Pediatric Endocrinology: Case-Based Approaches and Principles

By MedXY|Aug 28, 2026

This article explores ethical dilemmas in pediatric endocrinology through case studies, applying the four-principle framework to guide clinicians in managing complex patient scenarios effectively and compassionately.

Once-Weekly Somapacitan: A New Frontier in Growth Hormone Therapy for Girls with Turner Syndrome
Diabetes & Endocrinologygrowth hormone therapysomapacitan

Once-Weekly Somapacitan: A New Frontier in Growth Hormone Therapy for Girls with Turner Syndrome

By MedXY|Aug 4, 2026

A phase 3 trial demonstrates that once-weekly somapacitan is non-inferior to daily growth hormone injections in promoting linear growth in girls with Turner syndrome, offering a promising alternative with comparable safety and efficacy prof

Unraveling ROHHAD-NET Syndrome: Clinical Insights and the Role of Anti-ZSCAN1 Antibodies in Diagnosis and Management
Diabetes & Endocrinologyanti-ZSCAN1 antibodyautonomic dysregulation

Unraveling ROHHAD-NET Syndrome: Clinical Insights and the Role of Anti-ZSCAN1 Antibodies in Diagnosis and Management

By MedXY|Jul 19, 2026

This nationwide Japanese study elucidates early clinical features of ROHHAD-NET syndrome and highlights anti-ZSCAN1 antibody titers as potential biomarkers linked to neural crest tumors and treatment response.

Glucocorticoid Reduction After Starting Crinecerfont in Pediatric Patients With Classic CAH: Practical Perspectives
Diabetes & EndocrinologyCAHCrinecerfont

Glucocorticoid Reduction After Starting Crinecerfont in Pediatric Patients With Classic CAH: Practical Perspectives

By MedXY|May 10, 2026

New expert recommendations guide glucocorticoid dose reduction in pediatric classic CAH patients using crinecerfont, prioritizing normal growth while minimizing long-term steroid complications.

Endocrine Profile in Pediatric Bardet-Biedl Syndrome: Insights from a Large Multidisciplinary Cohort
Diabetes & EndocrinologyBardet-Biedl syndromeciliopathy

Endocrine Profile in Pediatric Bardet-Biedl Syndrome: Insights from a Large Multidisciplinary Cohort

By MedXY|Apr 28, 2026

A retrospective study of 135 pediatric BBS patients reveals high prevalence of obesity (77.6%) and short stature (21.1%), with low rates of hypogonadism, hypothyroidism, and glucose metabolism disorders compared to adult populations.

24-Weekly vs. 12-Weekly Triptorelin: Clinical Equivalence and Enhanced Adherence in Central Precocious Puberty
Diabetes & Endocrinologycentral precocious pubertyNội Tiết Học Nhi Khoa

24-Weekly vs. 12-Weekly Triptorelin: Clinical Equivalence and Enhanced Adherence in Central Precocious Puberty

By MedXY|Mar 7, 2026

A UK multicentre study demonstrates that 24-weekly Decapeptyl SR is as effective and well-tolerated as the 12-weekly regimen for central precocious puberty, offering improved patient satisfaction and reduced clinical burden.

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