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MedXY News/Oncology

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Oncology

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General Surgery

Temporary Portal Vein Bypass in Pancreatectomy: Enhancing Safety in Complex Pancreatic Cancer Surgery

Temporary mesoportal and mesocaval portal vein bypasses are effective surgical strategies in pancreatectomy with portal vein resection, offering comparable perioperative outcomes and facilitating safe resection of advanced pancreatic tumors

Oct 28, 2026
news

Optimizing Steroid Tapering Strategies for Immunotherapy Toxicities in Gynecologic Cancers

This study evaluates adherence to NCCN guidelines and taper durations of corticosteroids in managing severe immune-related adverse events (irAEs) among gynecologic cancer patients receiving immune checkpoint inhibitors, revealing that guide

Oct 28, 2026
Otorhinolaryngology

Swallowing Outcomes Following Early Treatment of Head and Neck Cancer-Related Lymphedema

Early intervention for head and neck cancer-related lymphedema significantly improves swallowing function and patient-reported outcomes, supporting timely multidisciplinary care.

Oct 27, 2026
General Surgery

Tailoring Prognostication in Pancreatic Ductal Adenocarcinoma: Impact of Neoadjuvant Therapy on Survival Predictors

Neoadjuvant therapy alters key prognostic factors in resected pancreatic ductal adenocarcinoma, enabling personalized survival prediction models distinct from chemo-naïve patients.

Oct 27, 2026
Oncology

Advancing Treatment in ER-Positive, HER2-Negative Advanced Breast Cancer: Efficacy of Giredestrant Plus Everolimus

A phase 3 trial demonstrates that the oral combination of giredestrant and everolimus significantly improves progression-free survival in patients with ER-positive, HER2-negative advanced breast cancer post-CDK4/6 inhibitor therapy, especia

Oct 27, 2026
General Surgery

Revolutionizing Biliary Tract Cancer Staging: Depth-Based Tumor Classification at the Cystic Duct Junction

A novel T classification system based on tumor invasion depth significantly improves prognostic stratification for biliary tract cancers around the cystic duct junction, unifying diverse cancer types under the junctional cholangiocarcinoma

Oct 27, 2026
news

Disparities in Immunotherapy Use for Advanced Endometrial Cancer Among Older Adults: Insights from NCDB Analysis

Immunotherapy use in older patients with advanced endometrial cancer has increased over recent years but remains lower among the oldest and racial minorities, highlighting persisting treatment disparities.

Oct 27, 2026
Plastic Surgery

Innovative Oncoplastic Breast Reconstruction: Efficacy and Versatility of J-Scar Mammaplasty

J-scar mammaplasty offers a safe, versatile level 2 oncoplastic technique with favorable aesthetic and oncologic outcomes, validated in a 157-patient study with low complication rates and high satisfaction.

Oct 26, 2026
news

Optimizing Neck Radiation in Advanced Differentiated Thyroid Carcinoma: Balancing Locoregional Control and Toxicity through Field Reduction

This study demonstrates that reducing radiation fields in advanced differentiated thyroid carcinoma lowers toxicity without compromising locoregional tumor control, supporting personalized radiotherapy strategies.

Oct 26, 2026
Dentistry

Optimizing Management of Medication-Related Osteonecrosis of the Jaw: Insights from a Single-Center Retrospective Cohort

This study evaluates outcomes of medication-related osteonecrosis of the jaw (MRONJ) treatments in 222 patients, highlighting the superiority of surgical interventions over conservative therapy, especially in osteoporosis-associated cases.

Oct 23, 2026
Clinical Updates

Integrating Body Composition Metrics for Prognostication in Head and Neck Cancer Radiotherapy: Advances and Clinical Implications

Recent evidence highlights the prognostic significance of body composition metrics, including BMI, skeletal muscle mass, and adiposity distribution, in head and neck cancer radiotherapy outcomes. Automated 3D CT phenotyping refines risk str

Oct 22, 2026
Gastroenterology

Optimizing Treatment Strategies for Gastric Cancer with Positive Peritoneal Cytology or Localized Peritoneal Metastasis

This article reviews a multicenter study comparing outcomes of different treatment approaches for gastric cancer patients with positive peritoneal cytology (CY1) and/or localized peritoneal metastasis (P1a), highlighting the superior surviv

Oct 22, 2026
Diabetes & Endocrinology

Long-Term Outcomes and Calcification Dynamics After Radiofrequency Ablation of Calcified Papillary Thyroid Microcarcinomas

This retrospective study demonstrates that radiofrequency ablation (RFA) effectively treats low-risk papillary thyroid microcarcinomas (PTMC), including those with intratumoral calcifications, with excellent technical success, significant t

Oct 22, 2026
Dermatology

Efficacy and Tolerability of Long-Term Low-Dose Capecitabine for Refractory Cutaneous Field Cancerization: Insights from a Retrospective Cohort Study

This study demonstrates that long-term, low-dose capecitabine significantly reduces keratinocyte carcinoma surgeries in patients with refractory cutaneous field cancerization and is generally well tolerated, offering a promising therapeutic

Oct 22, 2026
Hematology-Oncology

Ponatinib Plus Blinatumomab vs. Imatinib And Chemotherapy: Advancing Frontline Therapy in Adult Philadelphia-Positive ALL

This phase 3 trial demonstrates that a chemotherapy-free regimen combining ponatinib and blinatumomab significantly improves event-free survival over imatinib plus chemotherapy in adults with Philadelphia chromosome-positive acute lymphobla

Oct 21, 2026
Gastroenterology

Long-term Outcomes of Neoadjuvant Nivolumab and Ipilimumab in MSI-High Gastric and GEJ Adenocarcinoma: Insights from the Phase 2 NEONIPIGA Trial

The NEONIPIGA phase 2 trial demonstrates durable survival and high pathological complete response rates with neoadjuvant nivolumab and ipilimumab in localized MSI-high gastric and GEJ adenocarcinoma, highlighting potential for organ-preserv

Oct 21, 2026
Dermatology

Neutrophil-to-Lymphocyte Ratio as a Prognostic Biomarker in High-Risk Cutaneous Squamous Cell Carcinoma

Preoperative neutrophil-to-lymphocyte ratio (NLR) predicts poor outcomes in high-risk cutaneous squamous cell carcinoma, offering a cost-effective tool to enhance risk stratification.

Oct 21, 2026
news

Ocular Metastasis Over Four Decades: Clinical Patterns, Survival, and Therapeutic Outcomes in 569 Patients

A 40-year retrospective study of 569 patients with ocular metastases reveals persistently poor survival, dominated by breast and lung primaries, with vision often preserved through treatment despite no significant survival improvements over

Oct 20, 2026
news

HPV Positivity in Keratinizing Nasopharyngeal Carcinoma: Implications for Prognosis and Clinical Practice

HPV-positive keratinizing nasopharyngeal carcinoma demonstrates significantly improved overall survival compared to HPV-negative cases, underscoring the prognostic and clinical relevance of HPV testing in NPC management.

Oct 20, 2026
news

Impact of Patient-Level Social Determinants on Colon Cancer Outcomes: A Novel Prognostic Measure Within an Integrated Health Network

A new patient-level social determinants of health measure independently predicts advanced stage and survival outcomes in colon cancer patients, highlighting the importance of integrating social risk factors into oncologic care.

Oct 20, 2026
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Most read

  1. 01General Surgery

    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

  2. 02news

    Impact of Patient-Level Social Determinants on Colon Cancer Outcomes: A Novel Prognostic Measure Within an Integrated Health Network

  3. 03Hematology-Oncology

    Precision Immunotherapy in Acute Myeloid Leukemia: Advancing Beyond Traditional Targets

  4. 04General Surgery

    Maximizing Outcomes in Locally Advanced Pancreatic Cancer with Hypofractionated Ablative Radiation Therapy

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