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Neurology

Navigating the Risks of Enzyme-Inducing Antiseizure Medications and Hormonal Contraceptive Interactions in Women with Epilepsy

This article examines the prevalent coprescription of enzyme-inducing antiseizure medications (ASMs) and susceptible hormonal contraceptives among US Medicaid beneficiaries with epilepsy, highlighting patient risk factors and implications f

Oct 13, 2026
Diabetes & Endocrinology

Impact of School Care Locations on Glycemic Control in Children with Type 1 Diabetes: Insights from a Japanese Multicenter Study

This study explores how the choice of diabetes self-care location at school affects glycemic control in children with Type 1 diabetes, highlighting restroom use as a risk factor for poorer outcomes and emphasizing the need for supportive sc

Oct 13, 2026
Cardiology

Reducing Heat-Related Harm in People with Heart Disease: Key Recommendations from the 2026 European Heart Journal Consensus

An expert consensus provides practical, evidence-informed guidance for clinicians to protect people with cardiovascular disease from rising heat extremes, focusing on prevention, medication review, cooling strategies, and health-system prep

Oct 13, 2026
Internal Medicine

Removing unnecessary medical-clearance barriers: a patient-centred consensus for supporting people with long-term conditions to join organised physical activity

A multidisciplinary consensus offers patient-facing, evidence-based safety statements and symptom-specific guidance to replace routine medical clearance and reduce barriers to organised physical activity for people with long-term conditions

Oct 13, 2026
Neurology

Elevated Mental Health Risks in Adolescents Following Mild Traumatic Brain Injury: Insights from a Large Retrospective EHR Study

Adolescents who sustain mild traumatic brain injury (mTBI) face a significantly higher risk of developing mental health disorders over the subsequent year, influenced by factors such as sex, socioeconomic status, and prior psychiatric histo

Oct 13, 2026
news

Molecular Subtyping of Salivary Adenoid Cystic Carcinomas Enhances Prognostic Precision

This study uncovers molecular subtypes of salivary adenoid cystic carcinoma based on genomic and transcriptomic analyses, introducing a novel copy number variation (CNV)-based classification that improves prognostic accuracy and could refin

Oct 13, 2026Sign in to read
news

Evaluating the Impact of Multicancer Early-Detection Blood Tests on Late-Stage Cancer Diagnosis: Insights from a Large Randomized Trial

A large randomized trial assessing whether adding a blood-based multicancer early-detection test to usual care reduces late-stage cancer diagnoses found no significant difference in stage III or IV cancers but observed a trend toward fewer

Oct 13, 2026Sign in to read
news

Silk-Hyaluronic Acid Laryngoplasty: Evaluating Safety and Efficacy in Treating Glottic Insufficiency

Silk-hyaluronic acid injection laryngoplasty offers a safe, effective office-based treatment for glottic insufficiency, showing comparable voice improvement to hyaluronic acid alone but with higher rates of operative revisions.

Oct 12, 2026
General Surgery

Reevaluating Postoperative Antibiotic Use After Appendectomy in Acute Appendicitis: Insights from a Large Retrospective Study

A large retrospective study shows no benefit of routine postoperative antibiotics after appendectomy for acute appendicitis, even with intra-abdominal fluid; highlights risk factors driving infections instead.

Oct 12, 2026
news

Reducing Multiple Pregnancies After IVF: Practical Guidance from RCOG Scientific Impact Paper No.22 (3rd Ed., 2026)

The RCOG 2026 update stresses single embryo transfer, improved freezing, counselling and funding to prevent IVF multiple pregnancy and its harms while maintaining live-birth rates.

Oct 12, 2026
Gastroenterology

Outcomes and Mortality After Pediatric First Variceal Hemorrhage: Insights from a Global Multicenter Study

This international multicenter study reveals low immediate mortality after pediatric first variceal hemorrhage, with outcomes strongly influenced by underlying diagnosis, disease severity, and center-specific practices.

Oct 12, 2026
Neurology

Physical Activity and Motor and Cognitive Progression in Parkinson Disease: A Longitudinal Cohort Study

This study links higher physical activity levels with slower cognitive and motor decline in Parkinson’s disease, highlighting the importance of sustained activity engagement.

Oct 12, 2026Sign in to read
Diabetes & Endocrinology

Integrating Polygenic Risk Scores and Lifestyle Factors to Predict Type 2 Diabetes Onset in the Japanese Population

This study demonstrates that polygenic risk scores (PRS) independently predict type 2 diabetes risk in Japanese individuals, and healthy lifestyles can mitigate this risk even among genetically predisposed people, enhancing personalized pre

Oct 12, 2026
Neurology

Impact of OTC Analgesics on Concussion Recovery: Insights from the CARE Consortium Study

Over-the-counter analgesic use after concussion is linked to reduced symptom severity and faster return to unrestricted play, highlighting their potential role in postconcussion management.

Oct 12, 2026Sign in to read
Neurology

High Burden of Fall-Related Injuries Among Stroke Survivors in Ethiopia: Insights from a Multicenter Study in Amhara Region

A 2024 multicenter study in Amhara, Ethiopia found nearly 80% of stroke survivors experienced fall-related injuries, with older age, rural residency, and walking/turning activities as key risk factors.

Oct 12, 2026
news

Immune Profiling in Oral Tongue Dysplasia: Identifying Biomarkers to Stratify High-Risk Patients

This study identifies immune biomarkers, including proliferative CD8+ T cells, CD68+ macrophages, and PD-1 expression, which differentiate high-risk oral tongue epithelial dysplasia and may improve patient risk stratification beyond convent

Oct 12, 2026
news

Advancing Vision: Optogenetic Therapy Offers Hope for Retinitis Pigmentosa Patients

An open-label trial demonstrates the safety and potential efficacy of ChrimsonR-based optogenetic therapy combined with specialized goggles to enhance light sensitivity in patients with advanced retinitis pigmentosa, offering promising aven

Oct 12, 2026Sign in to read
Hematology-Oncology

Prognostic Significance of Telomere Length in Chronic Lymphocytic Leukemia Under Venetoclax-Based First-Line Therapy

Telomere length serves as an independent prognostic marker for progression-free survival in chronic lymphocytic leukemia patients treated with venetoclax-based regimens, highlighting its role in risk stratification during the modern targete

Oct 11, 2026
Hematology-Oncology

High Efficacy and Safety of Glofitamab Plus Polatuzumab-R-CHP in Newly Diagnosed Diffuse Large B-Cell Lymphoma: A Phase II Multicenter Study

A phase II trial shows that adding the bispecific antibody glofitamab to polatuzumab-R-CHP achieves a 95% complete response rate and durable remission with minimal cytokine release syndrome in high-risk diffuse large B-cell lymphoma.

Oct 11, 2026
Hematology-Oncology

Efficacy and Safety of Ziftomenib Combined with Venetoclax and Azacitidine in Relapsed/Refractory NPM1-Mutated Acute Myeloid Leukemia

This article reviews the KOMET-007 trial evaluating ziftomenib with venetoclax and azacitidine in relapsed/refractory NPM1-mutated AML, highlighting promising remission rates and manageable safety.

Oct 11, 2026Sign in to read
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  2. 02General Surgery

    Optimizing Postoperative Opioid Prescriptions After Intra-Abdominal Cancer Surgery: Comparing the 5x-Multiplier and 3-Tier Models

  3. 03news

    Inhaled Treprostinil in Idiopathic Pulmonary Fibrosis: Robust Evidence from the Combined TETON-1 and TETON-2 Phase 3 Trials

  4. 04news

    Impact of Patient-Level Social Determinants on Colon Cancer Outcomes: A Novel Prognostic Measure Within an Integrated Health Network

  5. 05news

    Is Vaginal Laxity in Women Really Caused by Frequent Sex? Debunking a Common Myth

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