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Lisocabtagene maraleucel shows sustained high remission rates and a favorable long-term safety profile in patients with heavily pretreated follicular lymphoma after three years of follow-up, including high-risk subgroups.
This study compares retreatment rates and timing in retinopathy of prematurity among infants treated with intravitreal bevacizumab versus laser therapy, highlighting lower early retreatment rates and delayed intervention in the bevacizumab
This study elucidates the intricate three-dimensional morphology and cellular organization of outer retinal tubulation (ORT) in Bietti crystalline dystrophy, revealing structural reorganization of residual outer retina with potential implic
This study evaluates the safety and clinical course of pregnant patients with idiopathic subglottic stenosis (iSGS), highlighting the need for operative intervention in over half and identifying antinuclear antibody positivity as a potentia
Postoperative pneumothorax after thyroid or parathyroid surgery is uncommon but linked with significantly increased mortality and complications, underscoring the need for vigilance and prompt management.
This mixed methods study details a six-year transition from total tonsillectomy to intracapsular tonsillectomy, highlighting improved postoperative outcomes and surgeon motivators behind adopting this safer surgical technique.
This study of 1,722 pancreaticoduodenectomies identifies key bleeding sources and predictors for severe postpancreatectomy hemorrhage, highlighting the roles of bile leak and infection in patients with pancreatic fistula and redefining cryp
Surgeons’ preoperative subjective assessments quantified by visual analog scale significantly predict severe postoperative complications, enhancing traditional risk models for better perioperative prognosis.
The SICE Liver ICG study demonstrated that indocyanine green fluorescence imaging significantly improves detection and margin assessment during minimally invasive, parenchymal-sparing liver resections for colorectal metastases, supporting m
A prospective cohort study demonstrates that a specialized multidisciplinary approach combining surgical and gastroenterological treatments significantly improves bowel function and quality of life in patients with low anterior resection sy
A large nationwide Danish survey reveals that chronic pain and sexual dysfunction are common long-term consequences following groin hernia repair in adolescents, underscoring the need for tailored surgical approaches and specialized care.
A state-level analysis reveals that child access prevention and concealed carry permitting laws could significantly reduce firearm suicide rates, potentially preventing over 110,000 deaths between 2010 and 2019.
This phase 1/2 study evaluates farletuzumab ecteribulin, a folate receptor alpha-targeting ADC, showing that fractionated dosing reduces interstitial lung disease risk and demonstrates preliminary antitumor activity in advanced ovarian, end
Despite menopause being a universal experience, many physicians lack adequate training in menopause care, resulting in unmet patient needs and increased reliance on unregulated sources. Medical education reforms are essential to close this
This review synthesizes recent evidence demonstrating persistent racial and ethnic disparities in treatment initiation and survival among patients with advanced endometrial cancer, highlighting the critical influence of socioeconomic status
Genetic susceptibility to metabolic dysfunction-associated steatotic liver disease (MASLD) is amplified by gut microbiota interactions, with ceramides playing a key role; targeted microbial interventions can reverse hepatic injury in at-ris
This multisite study identifies key clinical predictors including age, sex, BMI, diabetes, and prior neurotoxic treatments that contribute to chemotherapy-induced peripheral neurotoxicity (CIPN), affecting dose tolerance and long-term patie
This review synthesizes evidence on dual antiglutamate therapy combining AMPA and NMDA receptor blockade in postanoxic super-refractory status epilepticus, highlighting the SUPER-CAT study’s demonstration of improved seizure resolutio
Plasma pTau217 levels measured by Lumipulse G assays strongly correlate with postmortem temporal cortex pTau217 pathology, supporting plasma pTau217 as a reliable biomarker for brain tau pathology in Alzheimer disease.
Continuous ocrelizumab treatment over 10 years in relapsing MS significantly delays disability progression, reduces relapse rates, and maintains a favorable safety profile, underscoring the clinical benefit of early high-efficacy therapy.
