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Psychotherapy for Impact of Killing During War: Advancing Treatment of PTSD and Moral Injury in Veterans
Clinical Updatesveteranspsychotherapy

Psychotherapy for Impact of Killing During War: Advancing Treatment of PTSD and Moral Injury in Veterans

By MedXY|Aug 20, 2026

This review synthesizes evidence from a pivotal randomized clinical trial and complementary literature on psychotherapeutic interventions addressing the psychological impact of killing in war, emphasizing improvements in PTSD, moral injury,

Integrating Trauma-Focused Therapy with Cognitive Behavioural Therapy for Psychosis: Insights from the STAR Trial and Related Research
Clinical UpdatesCBTp
Psychosis

Integrating Trauma-Focused Therapy with Cognitive Behavioural Therapy for Psychosis: Insights from the STAR Trial and Related Research

By MedXY|Jul 12, 2026

The STAR trial demonstrates that trauma-focused CBTp is a safe, effective intervention for adults with co-occurring PTSD and psychosis, improving PTSD and psychosis symptoms, with high acceptability and minimal adverse events.

When the ICU Trauma Lingers: How Family PTSD Symptoms Build Across the Critical Illness Journey
Critical Carefamily distressICU

When the ICU Trauma Lingers: How Family PTSD Symptoms Build Across the Critical Illness Journey

By MedXY|Jun 19, 2026

Qualitative interviews show family PTSD after ICU care is shaped by cumulative stressors across the illness trajectory, highlighting the need for continuous, family-centered communication and support.

Digital Imagery-Competing Task Intervention Significantly Reduces Intrusive Memories in Trauma-Exposed Healthcare Staff: Evidence from the GAINS-02 Bayesian Trial
newsdigital healthhealthcare workers

Digital Imagery-Competing Task Intervention Significantly Reduces Intrusive Memories in Trauma-Exposed Healthcare Staff: Evidence from the GAINS-02 Bayesian Trial

By MedXY|Feb 25, 2026

A Bayesian adaptive randomized clinical trial reveals that a digital imagery-competing task intervention (ICTI) significantly reduces the frequency of intrusive memories and PTSD symptoms among healthcare workers exposed to pandemic-related

Rapid-Acting Neuroplastogen TSND-201 Shows Significant Efficacy in PTSD: Results from the Phase 2 IMPACT-1 Trial
newsPsychopharmacologyPTSD

Rapid-Acting Neuroplastogen TSND-201 Shows Significant Efficacy in PTSD: Results from the Phase 2 IMPACT-1 Trial

By MedXY|Feb 20, 2026

A Phase 2 randomized clinical trial demonstrates that TSND-201, a novel neuroplastogen, significantly reduces PTSD symptoms and functional disability without intensive psychotherapy, offering a potentially rapid and durable treatment option

Parental Firearm Injury Linked to Significant Surge in Pediatric Psychiatric Disorders and Mental Health Service Utilization
newsFirearm InjuryPediatric Mental Health

Parental Firearm Injury Linked to Significant Surge in Pediatric Psychiatric Disorders and Mental Health Service Utilization

By MedXY|Feb 2, 2026

A large-scale longitudinal study reveals that children whose parents suffer firearm injuries face a significant increase in psychiatric diagnoses, particularly trauma-related disorders. These findings highlight the profound secondary psycho

PTSD and Sleep Disorders Linked to Sharp Rise in Acute Coronary Syndrome Risk
Cardiologyacute coronary syndromeCardiology

PTSD and Sleep Disorders Linked to Sharp Rise in Acute Coronary Syndrome Risk

By MedXY|Jan 27, 2026

A comprehensive meta-analysis of over 22 million individuals identifies mental disorders, particularly PTSD and sleep disturbances, as major independent risk factors for acute coronary syndrome, urging a paradigm shift toward integrated car

Neuropsychiatric Interaction with Vascular Health: Deciphering the Moderating Role of PTSD in Hormonal Contraceptive-Associated Cardiovascular Risk
Clinical Updatescardiovascular healthHormonal Contraceptives

Neuropsychiatric Interaction with Vascular Health: Deciphering the Moderating Role of PTSD in Hormonal Contraceptive-Associated Cardiovascular Risk

By MedXY|Jan 6, 2026

A large-scale cohort study demonstrates that while hormonal contraceptives are generally associated with lower cardiovascular risk in women, this protective effect is lost in those with PTSD, highlighting a critical intersection between psy

The Limits of Collaborative Care: Why the CLARO Trial Found No Added Benefit for OUD and Comorbid Mental Illness
Internal Medicinecollaborative caredepression

The Limits of Collaborative Care: Why the CLARO Trial Found No Added Benefit for OUD and Comorbid Mental Illness

By MedXY|Jan 1, 2026

The CLARO randomized clinical trial investigated whether a collaborative care model could improve outcomes for patients with opioid use disorder and co-occurring depression or PTSD. The study found no statistically significant advantages ov

Delusional ICU Memories: The Hidden Driver of Long-Term Post-Traumatic Stress Disorder
Critical CaredeliriumPTSD

Delusional ICU Memories: The Hidden Driver of Long-Term Post-Traumatic Stress Disorder

By MedXY|Dec 27, 2025

This multicenter longitudinal study reveals that delusional memories, rather than simple amnesia, are the primary predictors of persistent PTSD symptoms following critical illness, highlighting the critical roles of delirium and sedation in

Psychedelics and MDMA for Mental Disorders: Promising Large Effects but Limited Certainty—What the Latest Living Meta-analysis Shows
newsmajor depressionMDMA

Psychedelics and MDMA for Mental Disorders: Promising Large Effects but Limited Certainty—What the Latest Living Meta-analysis Shows

By MedXY|Nov 25, 2025

A living systematic review of 30 RCTs (n=1,480) finds moderate-to-large symptom reductions for MDMA in PTSD and serotonergic psychedelics in major depression and anxiety, but high risk of bias and low certainty overall; pragmatic, longer, a

Comparative Effectiveness of PTSD Treatments in Primary Care: Insights from a Pragmatic Randomized Trial
Family Medicine & Nutritionprimary carepsychotherapy

Comparative Effectiveness of PTSD Treatments in Primary Care: Insights from a Pragmatic Randomized Trial

By MedXY|Oct 15, 2025

A pragmatic trial comparing SSRIs and written exposure therapy in primary care PTSD treatment found similar effectiveness initially; switching to SNRI was superior to WET augmentation for SSRI nonresponders.

Which Mental-Health Steps Should Trauma Teams Prioritize? A Practical Synthesis of New Guideline Recommendations
Emergency Medicineclinical practice guidelinesPTSD

Which Mental-Health Steps Should Trauma Teams Prioritize? A Practical Synthesis of New Guideline Recommendations

By MedXY|Oct 10, 2025

A systematic synthesis of clinical practice guideline recommendations for preventing and managing mental disorders after traumatic injury, with prioritized, implementable actions for acute and early recovery care.

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