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MedXY AI/MedXY News/Tag: pharmacoepidemiology
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Levothyroxine in the Ageing Patient: Re-evaluating Cardiovascular Outcomes in Subclinical Hypothyroidism through the ACEL-UK-ETT Trial
Cardiologygeriatric cardiologyLevothyroxine

Levothyroxine in the Ageing Patient: Re-evaluating Cardiovascular Outcomes in Subclinical Hypothyroidism through the ACEL-UK-ETT Trial

By MedXY|Mar 20, 2026

This review analyzes the ACEL-UK-ETT emulated target trial, demonstrating that long-term levothyroxine therapy in older adults with subclinical hypothyroidism significantly reduces cardiovascular events and all-cause mortality without compr

Oral Corticosteroids During Pregnancy: A Nationwide Study Reassures on Gestational Diabetes Risk
Internal MedicineGestational Diabetespharmacoepidemiology

Oral Corticosteroids During Pregnancy: A Nationwide Study Reassures on Gestational Diabetes Risk

By MedXY|Jan 1, 2026

A large-scale Korean cohort study involving 1.3 million pregnancies found no overall association between oral corticosteroid use and gestational diabetes risk, supporting their clinical use when indicated, despite a minor risk increase obse

SGLT2 Inhibitors Associated with Lower Risk of New-Onset Atopic Dermatitis in People with Type 2 Diabetes: Nationwide Active-Comparator Cohort Study
Dermatologyatopic dermatitisdiabetes

SGLT2 Inhibitors Associated with Lower Risk of New-Onset Atopic Dermatitis in People with Type 2 Diabetes: Nationwide Active-Comparator Cohort Study

By MedXY|Nov 1, 2025

A Taiwanese nationwide cohort study found SGLT2 inhibitor use linked to a lower incidence of new-onset atopic dermatitis versus DPP4 inhibitors (IPTW-adjusted HR 0.847), with a dose-response effect and stronger protection in men.

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