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SGLT2 Inhibitors Linked to Lower Risk of New-Onset Atopic Dermatitis in People with Type 2 Diabetes

MedXY Editorial Team•Nov 1, 2025•Dermatology
atopic dermatitisDPP‑4 inhibitorsSGLT2 inhibitorstype 2 diabetes

Highlights

– Nationwide active-comparator cohort (Taiwan NHID) compared SGLT2 inhibitors (n=148,354) with DPP‑4 inhibitors (n=322,703) for risk of new-onset atopic dermatitis (AD).

– SGLT2i use associated with lower AD incidence (9.742 vs 12.070 per 1,000 person‑years) and reduced risk (IPTW-adjusted HR 0.847) versus DPP‑4i.

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