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Transcriptomic analysis reveals age-related differences in levator ani muscle recovery after vaginal delivery, highlighting molecular pathways potentially contributing to pelvic organ prolapse risk in older first-time mothers.
This multicentre RCT demonstrates that perioperative vaginal oestrogen therapy improves patient-reported symptom relief and pelvic floor quality of life at 12 months post-prolapse surgery in postmenopausal women, without changing anatomical
A randomized controlled trial shows that adding electrical stimulation biofeedback to pelvic floor muscle training offers limited long-term anatomical improvement for postpartum pelvic organ prolapse but improves muscle strength without sig
A combined analysis of 704 women found that anterior-predominant and apical prolapse is the most common phenotype (67.2%) in women undergoing native tissue apical surgery. While symptomatic recurrence ranged from 0% to 29% across phenotype