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Brain Structure Changes in Chronic Cough: Insights from a Large-Scale Longitudinal Study
NeurologyneuroplasticityBrain Atrophy

Brain Structure Changes in Chronic Cough: Insights from a Large-Scale Longitudinal Study

By MedXY|Aug 11, 2026

This large-scale longitudinal study reveals that chronic cough is linked with widespread grey matter volume reductions and accelerated brain atrophy, highlighting potential neurostructural underpinnings of cough hypersensitivity.

Real-Time fMRI Neurofeedback Shows Promise for Reading Rehabilitation in Post-Stroke Aphasia
NeurologyAphasiafMRI neurofeedback

Real-Time fMRI Neurofeedback Shows Promise for Reading Rehabilitation in Post-Stroke Aphasia

© 2026 MedXY
Contact usAbout usPrivacy PolicyMedXY story
By MedXY|Apr 14, 2026

This feasibility RCT demonstrates that contingent fMRI neurofeedback targeting the left supramarginal gyrus can improve reading comprehension in stroke survivors with aphasia, outperforming both healthy controls and non-contingent neurofeed

Beyond Immersion: Why Combining Action Observation with Virtual Reality is a Game-Changer for Post-Stroke Hand Recovery
AIneuroplasticityQuan Sát Hành Động

Beyond Immersion: Why Combining Action Observation with Virtual Reality is a Game-Changer for Post-Stroke Hand Recovery

By MedXY|Mar 28, 2026

A multicenter randomized controlled trial reveals that integrating action observation with virtual reality significantly improves paretic hand dexterity in stroke patients, with benefits persisting six months post-intervention, offering a s

Exoskeleton-Assisted Therapy for Upper Limb Motor Recovery in Early Subacute Stroke: Evidence from a Multicenter Randomized Controlled Trial
Clinical UpdatesExoskeletonneuroplasticity

Exoskeleton-Assisted Therapy for Upper Limb Motor Recovery in Early Subacute Stroke: Evidence from a Multicenter Randomized Controlled Trial

By MedXY|Mar 13, 2026

A comprehensive review of a multicenter RCT (Morone et al., 2026) demonstrating that exoskeleton-based robot-assisted therapy significantly improves upper limb motor impairment and clinical outcomes in the early subacute phase of stroke rec

Challenging the ‘More is Better’ Paradigm: Intensive Training Shows No Added Benefit in Recent Spinal Cord Injury
Neurologyclinical trialsneuroplasticity

Challenging the ‘More is Better’ Paradigm: Intensive Training Shows No Added Benefit in Recent Spinal Cord Injury

By MedXY|Mar 9, 2026

A Phase 3 pragmatic trial found that 12 hours of weekly intensive task-specific training added to usual care does not improve motor recovery in recent spinal cord injury patients, suggesting a potential plateau in the benefits of early reha

Targeted Ipsilesional Training: A New Frontier for Enhancing Function in Severe Chronic Stroke
NeurologyIpsilesional Deficitsmotor recovery

Targeted Ipsilesional Training: A New Frontier for Enhancing Function in Severe Chronic Stroke

By MedXY|Feb 6, 2026

A randomized clinical trial reveals that targeted training of the ipsilesional arm significantly improves motor performance in chronic stroke patients with severe contralesional impairment, offering a sustained pathway to enhance functional

Miniaturized Closed-Loop Vagus Nerve Stimulation Drives Significant Functional Recovery in Chronic Stroke
Neurologyneuroplasticitystroke rehabilitation

Miniaturized Closed-Loop Vagus Nerve Stimulation Drives Significant Functional Recovery in Chronic Stroke

By MedXY|Jan 22, 2026

A randomized trial demonstrates that a 50-fold smaller, closed-loop vagus nerve stimulation (CLV) system is safe and significantly improves upper limb function in chronic stroke patients, with functional gains doubling during extended home-

High-Dose Walking Booster Program: A Feasible Strategy to Overcome Rehabilitation Plateaus in Chronic Stroke
Neurologyclinical trialsneuroplasticity

High-Dose Walking Booster Program: A Feasible Strategy to Overcome Rehabilitation Plateaus in Chronic Stroke

By MedXY|Jan 21, 2026

The Phase II HiWalk trial demonstrates that a 43-hour high-intensity walking booster program is safe and feasible for chronic stroke survivors, yielding significant walking speed improvements for individuals who have already completed their

Structured Walking Protocol Boosts Post-Stroke Recovery: Insights from the Walk ‘n Watch Trial
Neurologyclinical trialsneuroplasticity

Structured Walking Protocol Boosts Post-Stroke Recovery: Insights from the Walk ‘n Watch Trial

By MedXY|Dec 23, 2025

The Walk ‘n Watch trial shows that a structured, progressive walking protocol significantly improves endurance in subacute stroke patients, providing a 43.6-meter advantage over usual care without increasing serious adverse events.

Levodopa in Acute Stroke Rehabilitation: Insights from the ESTREL Randomized Clinical Trial
Neurologylevodopamotor recovery

Levodopa in Acute Stroke Rehabilitation: Insights from the ESTREL Randomized Clinical Trial

By MedXY|Oct 6, 2025

The ESTREL trial demonstrates that levodopa added to standardized rehabilitation does not significantly improve motor recovery after acute stroke, challenging its adjunctive use for enhancing neuroplasticity in stroke rehabilitation.

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