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Brain Structure Changes in Chronic Cough: Insights from a Large-Scale Longitudinal Study

MedXY Editorial Team•Aug 11, 2026•Neurology
neuroplasticityBrain Atrophygrey matter volumechronic cough

Highlight

  • Chronic cough is associated with significant grey matter volume reduction in multiple brain regions, particularly the right ventral striatum.
  • Sex differences observed with females showing more extensive and left-lateralized brain structural remodeling.
  • Chronic dry cough linked specifically to decreased grey matter in bilateral postcentral gyrus.
  • Longitudinal data indicate an accelerated rate of grey matter decline in cerebellar and other brain regions in chronic cough patients, suggesting dynamic neurostructural remodeling.

Study Background

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This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

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