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Polypharmacy Challenges in Older Adults with Metabolic Dysfunction-Associated Steatotic Liver Disease: Navigating Care in a High-Risk Population
Gastroenterologycardiometabolic diseasesMASLD

Polypharmacy Challenges in Older Adults with Metabolic Dysfunction-Associated Steatotic Liver Disease: Navigating Care in a High-Risk Population

By MedXY|Jul 17, 2026

Older adults with MASLD, especially those aged 75 and above, experience a high burden of polypharmacy linked to multimorbidity, necessitating careful medication management to balance disease control and geriatric vulnerabilities.

Provision of Primary Care Under Reduced Visit Time Pressures
Family Medicine & Nutritionappointment time
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care comprehensiveness

Provision of Primary Care Under Reduced Visit Time Pressures

By MedXY|May 18, 2026

Reduced visit time pressure in primary care was linked to slightly more diagnoses, prescriptions, and diagnostic testing, especially for patients with multiple chronic conditions. The study highlights how appointment scheduling can influenc

Earlier Menopause Linked to Accelerated Multimorbidity Progression: UK Biobank Multi-State Analysis Reveals Critical Windows for Preventive Intervention
newschronic diseaseMenopause

Earlier Menopause Linked to Accelerated Multimorbidity Progression: UK Biobank Multi-State Analysis Reveals Critical Windows for Preventive Intervention

By MedXY|Apr 6, 2026

A large UK Biobank cohort study of 121,017 postmenopausal women reveals that earlier menopause significantly increases risks of multimorbidity progression, with women experiencing premature menopause facing 32% higher risk of developing fir

Breaking the Silos: How the PACE-It Model Improves Outcomes in Multimorbid Patients through Integrated Social and Clinical Care
Diabetes & EndocrinologyDiabetes MellitusHealth-Social Integration

Breaking the Silos: How the PACE-It Model Improves Outcomes in Multimorbid Patients through Integrated Social and Clinical Care

By MedXY|Mar 14, 2026

The PACE-It pilot program demonstrates that integrating health and social care via multidisciplinary teams and technology significantly improves glycemic control, lipid management, and patient activation for individuals with complex needs,

Bridging the Health-Social Gap: The PACE-It Model Shows Promise for Complex Multimorbidity Management
Diabetes & Endocrinologydiabetes managementintegrated care

Bridging the Health-Social Gap: The PACE-It Model Shows Promise for Complex Multimorbidity Management

By MedXY|Mar 14, 2026

A pilot randomized controlled trial demonstrates that the PACE-It program, an integrated multidisciplinary team utilizing technology-assisted communication, significantly improves glycemic control, lipid management, and patient activation i

Mapping Multimorbidity in Severe Asthma: Defining Replicable Phenotypes to Optimize Personalized Care
Allergy & Immunologymultimorbidityprecision medicine

Mapping Multimorbidity in Severe Asthma: Defining Replicable Phenotypes to Optimize Personalized Care

By MedXY|Mar 3, 2026

This review analyzes findings from the pan-European SHARP registry study, identifying distinct multimorbidity phenotypes in severe asthma. It highlights the impact of steroid-associated and sinonasal clusters on clinical outcomes, advocatin

Childhood ADHD Traits Linked to Increased Risk of Physical Multimorbidity and Disability in Midlife
newsADHDchronic disease

Childhood ADHD Traits Linked to Increased Risk of Physical Multimorbidity and Disability in Midlife

By MedXY|Feb 12, 2026

A 46-year longitudinal study reveals that childhood ADHD traits significantly predict higher rates of physical health conditions, multimorbidity, and disability by middle age, mediated by modifiable risk factors like smoking, BMI, and psych

Dose-Response Risk: How Multiple Maternal Chronic Conditions Shape Neonatal Morbidity and Mortality
newsmaternal healthmultimorbidity

Dose-Response Risk: How Multiple Maternal Chronic Conditions Shape Neonatal Morbidity and Mortality

By MedXY|Feb 12, 2026

This population-based cohort study of over 1 million births reveals that maternal multiple chronic conditions (MCC) significantly increase the risk of severe neonatal morbidity and mortality, with risks escalating alongside the number, comp

Rethinking Rhythm Management: Catheter Ablation Outperforms Medical Therapy in Atrial Fibrillation Patients with High Comorbidity Burden
Cardiologyatrial fibrillationcatheter ablation

Rethinking Rhythm Management: Catheter Ablation Outperforms Medical Therapy in Atrial Fibrillation Patients with High Comorbidity Burden

By MedXY|Jan 21, 2026

A post hoc analysis of the CABANA trial reveals that catheter ablation significantly reduces major cardiovascular events and improves quality of life in AF patients with high comorbidity burden (≥4 conditions), suggesting that multimorbidit

Unraveling the Hidden and Measured Drivers of Chronic Disease Accumulation Across Organ Systems
Internal Medicinebiomarkerschronic disease

Unraveling the Hidden and Measured Drivers of Chronic Disease Accumulation Across Organ Systems

By MedXY|Oct 20, 2025

A 30-year birth cohort study reveals that life-course factors, especially modifiable markers like BMI, blood glucose, and blood pressure, significantly influence the buildup of chronic diseases across eight organ systems, yet much remains u

Impacts of Plant-Based Diets on Multimorbidity Risk in Cancer and Cardiometabolic Diseases Across Age Groups
Cardiologycancercardiometabolic diseases

Impacts of Plant-Based Diets on Multimorbidity Risk in Cancer and Cardiometabolic Diseases Across Age Groups

By MedXY|Oct 20, 2025

This analysis of EPIC and UK Biobank cohorts reveals that healthy plant-based diets reduce multimorbidity risk of cancer and cardiometabolic diseases, especially in middle-aged adults, underscoring diet’s role in chronic disease preve

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