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Frequency of Migraine and Sinus Headaches in Patients Undergoing Primary Rhinoplasty: A Clinical Review
Clinical UpdatesRhinoplastyMigraine

Frequency of Migraine and Sinus Headaches in Patients Undergoing Primary Rhinoplasty: A Clinical Review

By MedXY|Aug 7, 2026

This review analyzes the increased incidence of migraine and sinus headaches in primary rhinoplasty patients, emphasizing the clinical significance of screening rhinogenic headache triggers during septorhinoplasty to enhance both symptomati

Atogepant Shows Better Tolerability and Efficacy Than Topiramate in Migraine Prevention: TEMPLE Trial Results
NeurologyMigrainereflectance confocal microscopy

Atogepant Shows Better Tolerability and Efficacy Than Topiramate in Migraine Prevention: TEMPLE Trial Results

By MedXY|Jul 25, 2026

The phase 3b TEMPLE trial found that atogepant 60 mg once daily led to fewer discontinuations due to adverse events and better migraine reduction than topiramate over 24 weeks.

Postmenopausal Migraine Signals Higher Ischemic Stroke Risk, Not Hemorrhagic Stroke, in the Women’s Health Initiative
NeurologyWomen’s Health InitiativeMigraine

Postmenopausal Migraine Signals Higher Ischemic Stroke Risk, Not Hemorrhagic Stroke, in the Women’s Health Initiative

By MedXY|Aug 18, 2026

In a large cohort of postmenopausal women, migraine history was associated with a modest increase in ischemic stroke risk over 20 years, while total and hemorrhagic stroke risks were not significantly elevated.

A Pain-Predominant Dry Eye Phenotype Emerges: Severe Symptoms, Few Ocular Signs, and Strong Links to Migraine and Psychiatric Disease
Neurologydry eye diseaseMigraine

A Pain-Predominant Dry Eye Phenotype Emerges: Severe Symptoms, Few Ocular Signs, and Strong Links to Migraine and Psychiatric Disease

By MedXY|Jun 1, 2026

A 2026 Ophthalmology report identified a pain-predominant dry eye phenotype in 6.9% of patients, marked by high symptom burden, minimal surface signs, and enrichment for migraine and psychiatric comorbidity.

Neural Connectivity Patterns Predict Acupuncture Response in Migraine: A Step Toward Personalized Pain Management
NeurologyacupuncturefMRI

Neural Connectivity Patterns Predict Acupuncture Response in Migraine: A Step Toward Personalized Pain Management

By MedXY|Feb 10, 2026

This randomized clinical trial demonstrates that real acupuncture significantly reduces migraine frequency and disability compared to sham acupuncture. Crucially, baseline brain connectivity patterns within the default mode and subcortical

Candesartan 16 mg Emerges as a Robust, Evidence-Based Option for Migraine Prophylaxis
NeurologyCandesartanMigraine

Candesartan 16 mg Emerges as a Robust, Evidence-Based Option for Migraine Prophylaxis

By MedXY|Dec 23, 2025

A Phase 2 triple-blind trial confirms that 16 mg of candesartan daily significantly reduces monthly migraine days compared to placebo, offering a well-tolerated oral alternative for patients with episodic migraine.

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