Section
This randomized trial found that larger doses of bupivacaine for sphenopalatine ganglion block did not improve sustained headache relief in emergency patients compared to smaller doses, with good tolerability across all doses.
Etiologic investigations after status epilepticus (SE) demonstrate variable diagnostic yield and significantly influence treatment decisions, especially when guided by clinical pretest probability. Tailored diagnostic strategies enhance tim
This study introduces a standardized 5-class framework for tau PET imaging to better detect and stage Alzheimer’s disease, improving early diagnosis and patient stratification across different tracers.
This study evaluates risk factors for intracranial haemorrhage after tenecteplase fibrinolysis in STEMI patients, developing a prediction model highlighting age, blood pressure, sex, weight, and dose interactions as key determinants.
This study delineates how vascular imaging morphologies, notably the double lumen sign, predict time-specific recurrence risk after craniocervical artery dissection, highlighting the hyperacute phase as critical for secondary prevention.
Longitudinal EEG analysis in infants with CDKL5 deficiency disorder reveals progressive background abnormalities and specific seizure phenotypes correlating with developmental severity within the first two years of life.
This study reveals significant associations between high-level blast exposure during military service and increased risk for chronic health conditions in US Veterans, emphasizing the long-term occupational hazards of blast injuries.
This longitudinal study shows that retinal microvascular changes measured by OCTA correspond with cerebral small vessel disease progression and cognitive decline in mild ischemic stroke patients, highlighting OCTA’s potential as a non
This study identifies systemic pathological pathways that mediate blood-brain barrier injury in sickle cell disease, linking BBB disruption to brain hypoxia and microstructural injury, highlighting new therapeutic targets to preserve neurol
This study demonstrates that arterial spin labeling spatial coefficient of variation (ASL-sCoV) correlates with cerebral small vessel disease burden and predicts cognitive decline over 11 years, outperforming traditional cerebral blood flow
Postacute discharge to inpatient rehabilitation facilities (IRF) after acute ischemic stroke (AIS) is associated with a reduced 1-year risk of major adverse cardiovascular events (MACE) compared to discharge to home or skilled nursing facil
This study analyzes national trends in emergent interfacility ischemic stroke transfers among Medicare beneficiaries, revealing shifts in transfer rates, patient characteristics, and hospital features associated with transferred versus nont
Kynurenic acid (KYNA) reduction in the gut correlates with worse poststroke outcomes. Supplementation activates a gut-brain neural circuit via GPR35 and the vagus nerve, promoting neuroprotection and functional recovery after ischemic strok
SGLT2 inhibitors administered after endovascular thrombectomy in diabetic stroke patients significantly improve 3-month functional outcomes, suggesting a promising adjunctive therapy for poststroke diabetes management.
This comparative analysis assesses ischemic stroke outcomes in patients with asymptomatic carotid stenosis undergoing transcarotid artery revascularization (TCAR) versus carotid artery stenting (CAS), highlighting no significant difference
This review synthesizes longitudinal evidence linking early adulthood vascular risks, particularly elevated systolic blood pressure and smoking, to midlife cognitive decline and brain structural alterations. It highlights critical intervent
The CREST-2 trial substantiates carotid artery stenting plus intensive medical management significantly reduces stroke risk in high-grade asymptomatic carotid stenosis compared to medical therapy alone, emphasizing patient selection and pro
A recent randomized trial shows that adding intravenous immunoglobulin (IVIG) to high-dose prednisone significantly improves muscle strength and disease activity in newly diagnosed idiopathic inflammatory myopathies with rapid and clinicall
In patients with distal and medium vessel occlusion strokes, tenecteplase achieves higher early recanalization rates and reduces early infarct growth compared to alteplase, supporting its preferential use in this clinical setting.
This study evaluates vessel wall MRI (VW-MRI) in pediatric arterial ischemic stroke, highlighting its diagnostic role in detecting inflammatory arteriopathies but limited prognostic value for long-term outcomes.
