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Medicare Advantage (MA) shows no significant improvement over original Medicare (OM) in managing type 2 diabetes outcomes or mitigating related social needs despite higher costs, underscoring the need for effective spending strategies.
A large Latin American study shows radiofrequency ablation is a safe, effective minimally invasive alternative for T1a low-risk papillary thyroid cancer, with excellent tumor disappearance rates and minimal complications over 18 months foll
This study reveals that reduced arginine availability during hyperglycaemia distinguishes A-β+ ketosis-prone diabetes from type 2 diabetes, implicating impaired arginine metabolism in ketoacidosis pathogenesis and highlighting citrulline su
Levothyroxine treatment in older adults with subclinical hypothyroidism shows limited impact on cardiometabolic biomarkers overall but may benefit those with higher TSH levels, highlighting nuanced treatment implications and the need for ta
This study reveals that housing instability among adults with uncontrolled diabetes is associated with increased financial strain and cost-related medication nonadherence, underscoring the need for holistic approaches to diabetes care invol
COMBINE 4 demonstrated that once-weekly IcoSema (icodec+semaglutide) offers superior glycemic control, weight reduction, and reduced hypoglycemia versus daily insulin glargine U100 in insulin-naive type 2 diabetes patients, supported by com
This review integrates recent randomized trial data with observational studies to clarify cannabis inhalation’s acute impact on cardiac ectopy, physical activity, sleep, and glucose, highlighting complex arrhythmia associations and cl
This study reveals a significant early onset of metabolic syndrome in men with prostate cancer treated with combined ADT and ARPI therapies, highlighting the necessity for multidisciplinary metabolic monitoring and interventions.
We report five pediatric MEN2B cases highlighting early extra-endocrine signs such as persistent constipation and alacrimia, enabling prompt genetic diagnosis and thyroidectomy before medullary thyroid carcinoma progression.
This study investigates how semaglutide exposure before and during pregnancy affects gestational weight gain and key pregnancy outcomes in women with overweight or obesity, highlighting increased risks that may stem from treatment discontin
A new sonographic pattern characterized by discontinuous peripheral punctate echogenic foci (DPEF) in thyroid nodules is strongly associated with papillary thyroid carcinoma (PTC), suggesting its potential as an important diagnostic marker
This study reveals a high heart failure risk within 5 years of diabetes diagnosis, highlighting insulin resistance and reduced kidney function as independent predictors beyond conventional risk factors.
A phase II basket trial demonstrates that vosoritide significantly increases growth velocity in children with RASopathies, ACAN, and NPR2 deficiencies, with an acceptable short-term safety profile, suggesting its potential as a precision th
This study reveals significant HbA1c and glucose discrepancies, especially in Black individuals, and introduces a personalized HbA1c correction (pA1C) that enhances diabetes management across racial groups.
A novel enzymatic assay measuring fasting 2-hydroxybutyrate shows high accuracy in identifying postprandial dysglycemia in individuals with normal fasting glucose and HbA1c, offering an improved screening approach for early glucose metaboli
Normothermic regional perfusion (NRP) offers a promising approach to reduce ischemic injury in pancreas and islet transplantation using donation after circulatory death (DCD) donors, improving graft quality and expanding donor availability.
A novel longitudinal obesity medicine training pathway for internal medicine residents, implemented at an urban Federally Qualified Health Center, improves physician confidence and management skills in obesity care, preparing trainees for b
This study examines how bariatric surgery and gestational diabetes mellitus independently and jointly impact maternal and neonatal outcomes, highlighting increased risks and the need for personalized antenatal care.
The TC-MAX is the first validated, disease-specific instrument measuring thyroid cancer-related anxiety, showing strong reliability and validity to inform treatment decisions and improve patient-centered care.
Concurrent exercise added to a palaeolithic diet improves cardiometabolic fitness and post-exercise clearance of ceramides, enhancing fat oxidation in individuals with type 2 diabetes.
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